A5008011670- Effects and risks of endocrine disrupting chemicals
- Per- and polyfluoroalkyl substances research
- Health, Environment, Cognitive Aging
- Air Quality and Health Impacts
- Toxic Organic Pollutants Impact
- Carcinogens and Genotoxicity Assessment
- Animal testing and alternatives
- Research Data Management Practices
- Agricultural safety and regulations
- Recycling and Waste Management Techniques
- Microplastics and Plastic Pollution
- Climate Change and Health Impacts
- Birth, Development, and Health
- Chemical Safety and Risk Management
- Nutritional Studies and Diet
- Pharmaceutical studies and practices
- Atmospheric chemistry and aerosols
- Air Quality Monitoring and Forecasting
- Scientific Computing and Data Management
- Occupational and environmental lung diseases
- COVID-19 epidemiological studies
- Vitamin D Research Studies
- Delphi Technique in Research
- Environmental Justice and Health Disparities
- Gestational Diabetes Research and Management
National Institute for Public Health and the Environment
2021-2024
Shell (Netherlands)
2024
University of Padua
2019-2021
Wageningen University & Research
2018-2021
Mario Negri Institute for Pharmacological Research
2020
European Food Safety Authority
2020
Regione del Veneto
2020
London School of Hygiene & Tropical Medicine
2020
Public Health Department
2020
Weatherford College
2020
This Guidance document describes harmonised risk assessment methodologies for combined exposure to multiple chemicals all relevant areas within EFSA's remit, i.e. human health, animal health and ecological areas. First, a short review of the key terms, scientific basis approaches assessing (eco)toxicology is given, including existing frameworks these assessments. background was evaluated, resulting in framework chemicals. The based on steps (problem formulation, assessment, hazard...
This paper presents an analysis of risk mitigation measures taken by countries around the world facing current COVID-19 outbreak. In light pandemic authors collated and clustered (using harmonised terminology) globe in combat to contain, since March 11, 2020, limit spread SARS-CoV-2 virus known cause Coronavirus disease 2019 (COVID-19). overview gathers lessons learnt, providing update on knowledge for authorities, sectors first responders effectiveness said measures, may allow enhanced...
In spring 2013, groundwater of a vast area the Veneto Region (northeastern Italy) was found to be contaminated by perfluoroalkyl substances (PFAS) from PFAS manufacturing plant active since late 1960s. Residents were exposed high concentrations PFAS, particularly perfluorooctanoic acid (PFOA), through drinking water until autumn 2013. A publicly funded health surveillance program is under way aid in prevention, early diagnosis, and treatment chronic disorders possibly associated with exposure.
Residents of a large area the Veneto Region (North-Eastern Italy) were exposed for decades to drinking water contaminated by perfluoroalkyl substances (PFAS). PFAS have been consistently associated with raised serum lipids, mainly in cross-sectional studies and background exposure contexts, but shape dose-response relationships has poorly investigated. The objectives our study evaluate association between lipids their patterns population. A was conducted 16,224 individuals aged 20–39 years...
Human health risk assessment is historically built upon animal testing, often following Organisation for Economic Co-operation and Development (OECD) test guidelines exposure assessments. Using combinations of human relevant in vitro models, chemical analysis computational (in silico) approaches bring advantages compared to studies. These include a greater focus on the species molecular mechanisms kinetics, identification Adverse Outcome Pathways downstream Key Events as well possibility...
Bisphenol A as an endocrine-disrupting chemical is widely used in the manufacture of polycarbonate plastics and epoxy resin has become ubiquitous environmental contaminants. Human exposure to widespread recent studies have been shown be associated with a higher risk for self-reported adverse health outcomes that may lead insulin resistance development type-2 diabetes mellitus. In this context, we sought confirm association between community-based analysis urinary concentrations investigation...
Abstract Background Residents in a large area of North-Eastern Italy were exposed to perfluoroalkyl substances (PFAS) via drinking water. Studies on the association between PFAS and blood pressure levels are limited, results inconsistent. Using cross-sectional data from Regional health surveillance program, we aimed quantify associations serum concentrations hypertension prevalence. Methods The study comprised 16,224 individuals aged 20–39 years. Pregnant women ( n = 327), or with missing...
In this paper, the European chapter of International Society for Exposure Science (ISES Europe) provides a vision on how dietary exposure sciences can contribute to address challenges in field food safety and nutrition due changes systems by answering following question: How we assess timely accurately hazardous chemicals (and mixtures thereof) or intake nutrients production, consumption composition? We first describe current role instruments that are being used nutrition. This is followed...
Human biomonitoring (HBM) data measured in specific contexts or populations provide information for comparing population exposures. There are numerous health-based guidance values, but to locate these interested parties need seek them out individually from publications, governmental reports, websites and other sources. Until now, there has been no central, international repository this information. Thus, a tool is needed help researchers, public health professionals, risk assessors,...
Safe and sustainable chemicals/materials are critical for achieving European green goals. The novel SSbD framework aims to harmonize assessments during innovation. Here, we discuss the essential role of FAIR data tools in operationalizing SSbD.
Biomonitoring has been widely used in assessing exposures both occupational and public health complementing chemical risk assessments because it measures the concentrations of substances human body fluids (e.g., urine blood). considers all routes sources exposure. An biomonitoring guidance document elaborated (OECD Occupational Guidance) within OECD framework specifically, Working Parties on Exposure Hazard Assessment by scientific experts from 40 institutes organizations representing 15...
A method was developed for the extraction of phthalic acid esters (PAEs) from bottled water. Surface-functionalized magnetic particles (MPs) were used as adsorbent solid-phase (MSPE). The MPs prepared by using both polydimethylsiloxane and multiwalled carbon nanotubes. By coupling MSPE with GC–MS instrument, a reliable, sensitive cost-effective simultaneous determination six main PAEs including dimethyl phthalate (DMP), diethyl (DEP), dibutyl (DBP), butyl benzyl phthalate, di-n-octyl...