Saad Akhtar

ORCID: 0000-0002-4294-0944
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About
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Research Areas
  • Lymphoma Diagnosis and Treatment
  • CNS Lymphoma Diagnosis and Treatment
  • Viral-associated cancers and disorders
  • Lung Cancer Treatments and Mutations
  • Chronic Lymphocytic Leukemia Research
  • Genetic factors in colorectal cancer
  • Neuroendocrine Tumor Research Advances
  • Multiple and Secondary Primary Cancers
  • Acute Lymphoblastic Leukemia research
  • Head and Neck Cancer Studies
  • CAR-T cell therapy research
  • Salivary Gland Tumors Diagnosis and Treatment
  • Polyomavirus and related diseases
  • Lung Cancer Research Studies
  • Medical Imaging and Pathology Studies
  • Head and Neck Surgical Oncology
  • Sarcoma Diagnosis and Treatment
  • Childhood Cancer Survivors' Quality of Life
  • Sinusitis and nasal conditions
  • Medical Imaging Techniques and Applications
  • Breast Cancer Treatment Studies
  • Cancer survivorship and care
  • Cancer Treatment and Pharmacology
  • Ovarian cancer diagnosis and treatment
  • Nonmelanoma Skin Cancer Studies

King Faisal Specialist Hospital & Research Centre
2015-2024

Royal Preston Hospital
2006-2024

Alfaisal University
2023

University of Karachi
2015-2022

Albany Medical Center Hospital
2021-2022

Institute of Child Health
2020

European Society for Blood and Marrow Transplantation
2016-2017

Burn Institute
2012

Princess Margaret Cancer Centre
2008

King Faisal University
2008

Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare cancer, and large international cooperative efforts are needed to evaluate the significance of clinical risk factors immunoarchitectural patterns (IAPs) for all stages pediatric adult patients with NLPHL.

10.1200/jco.23.01655 article EN Journal of Clinical Oncology 2024-03-26

From 1996 to April 2006, 174 consecutive patients with relapsed or refractory diffuse large cell lymphoma (DLCL) and Hodgkin (HL) received ESHAP as salvage for mobilisation. Males 92, females 76. DLCL 64: HL 104, prior radiation in 35%. First relapse 45%, second 12%, induction failure 43%. Median chemotherapy cycles were 6. age at apheresis was 26.5 years. Six failed mobilisation 21 had CD34+ cells collection <2×106/kg on first apheresis. cells/kg 5.5×106/kg 6.7×106/kg all We evaluated...

10.1080/10428190701843213 article EN Leukemia & lymphoma/Leukemia and lymphoma 2008-01-01

Lymphoma is one of the most common malignancies affecting young Saudi population. This disease has diversified pathologies and clinical stages that necessitate well optimized management. Regular updates epidemiological behavior lymphoma from various parts world are available but studies Kingdom Arabia (KSA) in this field not consistent.The aim study was to investigate current trends presentation distribution with special reference incidence mortality, gender, age, histopathological subtypes,...

10.7314/apjcp.2015.16.5.2069 article EN cc-by Asian Pacific Journal of Cancer Prevention 2015-03-18

Whilst autologous stem cell transplantation (auto-SCT) is considered standard of care for relapsed/refractory classical Hodgkin lymphoma, the role auto-SCT in nodular lymphocyte-predominant lymphoma (NLPHL) not well defined due to limited data. We report first study on NLPHL with a larger cohort. Eligible this retrospective registry were patients reported EBMT between 2003 and 2013, aged 18 or older who underwent disease chemosensitive salvage therapy. transformed diffuse large B excluded....

10.1002/ajh.24927 article EN American Journal of Hematology 2017-10-03

Rituximab with anthracycline-based combination frontline chemoimmunotherapy can cure 50-60% of patients diffuse large B-cell lymphoma (DLBCL). However, studies on the outcomes DLBCL who experience partial response (PR), stable or progressive disease in to rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (RCHOP) therapy are limited, as data high-dose chemotherapy (HDC) autologous stem cell transplantation (ASCT) primary refractory demonstrate chemosensitivity salvage...

10.46989/001c.115919 article EN cc-by Clinical Hematology International 2024-04-10

Abstract Primary lymphoma of the female genital tract (PLFGT) is a rare type extranodal lymphoma. In this retrospective study from International Extranodal Lymphoma Study Group, we analyzed clinical data 60 women diagnosed with PLFGT between 1982 and 2012. The median age was 52 years. Limited stage, as defined by Ann Arbor FIGO staging systems, observed in 55% 63% cases, respectively. uterus primary site 25 ovaries second most common ( n = 24). histological subtype diffuse large B‐cell...

10.1002/hon.3312 article EN cc-by Hematological Oncology 2024-09-26

Study Type – Therapy (individual cohort) Level of Evidence 2b What’s known on the subject? and What does study add? BCG is standard treatment for superficial bladder cancer. The combination interferon‐alfa may be more effective less toxic than alone. With long term follow up efficacy toxicity combined intravesical interferon‐α alone seems to equal in OBJECTIVE • To evaluate bacillus Calmette‐Guérin (BCG) interferon α‐2B (IFNα‐2B) treating cancer (SBC). mentioned has shown synergism...

10.1111/j.1464-410x.2010.10040.x article EN BJU International 2011-02-18

Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) has been translated from English into several languages. Currently, there is no validated translation FACT-BMT in Arabic. Here, we are reporting the first Arabic and validation FACT-BMT. The study was approved by Institutional Research Advisory Council. followed standard Chronic Illness Therapy (FACIT.org) methodology (with permission). (50- items) statistically validated. Cronbach's alpha for internal consistency,...

10.1186/s12955-018-0861-7 article EN cc-by Health and Quality of Life Outcomes 2018-03-12

B-HOLISTIC was a real-world, retrospective study of treatment patterns and clinical outcomes in Hodgkin lymphoma (HL) regions outside Europe North America. This subgroup analysis reports findings from Saudi Arabia, Türkiye, South Africa.

10.4274/tjh.galenos.2024.2024.0181 article EN cc-by-nc-nd Turkish Journal of Hematology 2024-10-24

Data are limited regarding the prevalence of menstrual cycles and pregnancies after high-dose chemotherapy (HDC) auto-stem cell transplantation (SCT). Female patients who underwent HDC auto-SCT for non-Hodgkin Hodgkin lymphoma (1997-2012) were reviewed. The selection criteria as follows: (1) alive without disease 12 24 months pregnancy, respectively, (2) age <40 years at auto-SCT, (3) no primary infertility. One-hundred seventy-six females single auto-SCT. Eighty-nine eligible pregnancy...

10.1038/bmt.2015.178 article EN cc-by-nc-nd Bone Marrow Transplantation 2015-08-03
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