A5008227221- Childhood Cancer Survivors' Quality of Life
- Palliative Care and End-of-Life Issues
- Ethics and Legal Issues in Pediatric Healthcare
- Family and Patient Care in Intensive Care Units
- Lymphoma Diagnosis and Treatment
- Healthcare professionals’ stress and burnout
- Patient-Provider Communication in Healthcare
- Family Support in Illness
- Ethics in Clinical Research
- Adolescent and Pediatric Healthcare
- CAR-T cell therapy research
- Optimism, Hope, and Well-being
- Nursing education and management
- Anesthesia and Neurotoxicity Research
- Grief, Bereavement, and Mental Health
- Inflammatory Bowel Disease
- Gastrointestinal motility and disorders
- Innovations in Medical Education
- Religion, Spirituality, and Psychology
- Blood disorders and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Interpreting and Communication in Healthcare
- Health and Medical Research Impacts
- Patient Safety and Medication Errors
- Colorectal and Anal Carcinomas
Indiana University School of Medicine
2021-2024
Riley Hospital for Children
2022-2024
Indiana University – Purdue University Indianapolis
2021-2024
Indiana University Health
2022-2024
Indiana University
2021-2022
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
2022
St. Jude Children's Research Hospital
2017-2021
University School
2021
Washington University in St. Louis
2021
University of Pittsburgh Medical Center
2008
BACKGROUND: When children are seriously ill, parents rely on communication with their clinicians. However, in previous research, researchers have not defined how this should function pediatric oncology. We aimed to identify these functions from parental perspectives. METHODS: Semistructured interviews 78 of cancer 3 academic medical centers at 1 time points: treatment, survivorship, or bereavement. analyzed interview transcripts using inductive and deductive coding. RESULTS: identified 8...
Abstract Background The field of pediatric palliative oncology is newly emerging. Little known about the characteristics and illness experiences children with cancer who receive care (PC). Methods A retrospective cohort study 321 patients enrolled in PC died between 2011 2015 was conducted at a large academic center using comprehensive standardized data extraction tool. Results majority received experimental therapy (79.4%), 40.5% on phase I trial. Approximately one‐third cancer‐directed...
Introduction: Communication failures are common root causes of serious medical errors. Standardized, structured handoffs improve communication and patient safety. I-PASS is a handoff program that decreases errors preventable harm. The mnemonic defined as illness severity, information, action list, situational awareness contingency plans, synthesis by receiver. was validated for physician handoffs, yet has the potential broader application. objectives this quality improvement initiative were...
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare cancer, and large international cooperative efforts are needed to evaluate the significance of clinical risk factors immunoarchitectural patterns (IAPs) for all stages pediatric adult patients with NLPHL.
Background: Core binding factor acute myeloid leukemia (AML) is a common type of pediatric AML characterized by inv(16) or t (8;21) lesions that inhibit the function core complex.Although these rearrangements are considered favorable risk in AML, nearly 30% children with will relapse, indicating continued need for improved understanding biology and new therapeutic targets.Mutations cohesin complex genes occur commonly t(8;21) but never found inv( 16) suggesting unique role pathophysiology...
Background: Racial and ethnic disparities in the provision of end-of-life care are well described adult oncology literature. However, impact racial at end life context pediatric remains poorly understood. Objective: To investigate associations between experiences race/ethnicity for patients with cancer. Methods: A retrospective cohort study was conducted on 321 children cancer enrolled a palliative service an urban who died 2011 2015. Results: Compared to white patients, black were more...
* Abbreviation: HOPE — : Hear Our Parent Experiences Parents of children with serious illness often maintain hope across a child's journey. Historically, the conflict between parental and prognostic acceptance has been described as pendulum oscillating antithetical states awareness. In this commentary, bereaved parents partner interdisciplinary pediatric palliative care clinicians to discuss challenge conventional theory in which realism exist diametrically opposing spaces within vacillate....
Persons who speak languages other than English are underrepresented in clinical trials, likely part because of inadequate multilevel resources. We conducted a survey institutions affiliated with the Children's Oncology Group (COG) to characterize current research recruitment practices and resources regarding translation interpretation services.
Abstract Background In the U.S., more children die from cancer than any other disease, and one third in hospital setting. These data have been replicated even subpopulations of with enrolled on a palliative care service. Children who high-acuity inpatient settings often experience suffering at end life, increased psychosocial morbidities seen their bereaved parents. Strategies to preemptively identify are likely not explored. Materials Methods A standardized tool was used gather demographic,...
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Aggressive Mature B-Cell Lymphomas include recommendations the diagnosis and management of pediatric patients with primary mediastinal large B-cell lymphoma (PMBL) sporadic variants Burkitt diffuse lymphoma. PMBL is now considered as a distinct entity arising from mature thymic B-cells accounting 2% lymphomas children adolescents. This discussion section includes outlined PMBL.
PURPOSE: Communication breakdowns in pediatric oncology can have negative consequences for patients and families. A detailed analysis of these encounters will support clinicians anticipating responding to communication breakdowns. METHODS: Semistructured interviews with 80 parents children cancer across three academic medical centers during treatment, survivorship, or bereavement. We analyzed transcripts using semantic content analysis. RESULTS: Nearly all identified experiences (n = 76)....
Abstract Background Increasing representation in clinical trials is a priority for the National Cancer Institute and Children's Oncology Group (COG). Our survey of COG‐affiliated institutions revealed that many sites have insufficient processes resources to enroll children whose parents use languages other than English (LOE). We describe reported barriers facilitators enrolling when LOE propose opportunities improvement. Procedures sent 20‐item institutions. Five items allowed respondents...
Abstract Background Parents and clinicians of children with cancer can provide advice to improve communication that reflects lessons learned through experience. We aimed identify categories offered parents from other parents. Procedure (1) Semi‐structured interviews 80 at three sites; (2) single‐item, open‐ended survey administered following 10 focus groups 58 pediatric oncology two sites. asked participants for parents, analyzed responses using semantic content analysis. Results provided...
Abstract Background Workplace burnout can result in negative consequences for clinicians and patients. We assessed prevalence sources among pediatric hematology/oncology inpatient nurses, ambulatory physicians (MDs), advanced practice providers (APPs) by evaluating effects of job demands involvement patient safety events (PSEs). Methods A cross‐sectional survey (Maslach Burnout Inventory) measured emotional exhaustion, depersonalization, reduced personal accomplishment. The National...
Religion and spirituality often influence how people experience illness, death, grief. The roles of religion for parents who have lost a child to cancer remain underexplored. This study aimed describe cancer-bereaved talk about when reflecting on their experiences. Participants whose children died one six years prior participation completed one-on-one semi-structured interview. Interview transcripts underwent qualitative analysis. Content pertaining and/or subsequent in-depth analysis...
Compared with younger children and older adults, adolescent young adult (AYA) patients cancer receive more intensive end-of-life (EOL) care. We hypothesize that enhanced understanding of AYA preferences, increased engagement these in decision-making, improved communication their preferences family members the medical team will lead to provision goal-concordant care decreased intensity EOL In this study, we describe development a novel tool quantifies relative importance numerous factors...
Effective communication is integral to patient and family-centered care in pediatric adolescent young adult (AYA) oncology improving healthcare delivery outcomes. There limited knowledge about whether AYAs parents have similar preferences needs. By eliciting comparing advice from parents, we can identify salient guidance for how clinicians better communicate. We performed secondary analysis of semi-structured interviews 2 qualitative studies. In one study, 80 children with cancer during...
Burnout is a syndrome of emotional exhaustion, depersonalization, and reduced personal accomplishment because chronic occupational stress. Approximately one third pediatric hematology-oncology physicians experience burnout. The goal this mixed methods study was to determine the prevalence drivers burnout among caring for patients at our institution.This methods, cross-sectional conducted large academic cancer center. Validated survey instruments were used measure burnout, job demands, with...
Background: Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare cancer, and large studies evaluating outcomes for patients with scoring of immunoarchitectural patterns (IAPs) are needed. We performed an international study pediatric adult all stages NLPHL. Methods: Thirty-seven centers participated in the Global nLPHL One Working Group to retrospectively identify NLPHL cases from 1992-2021. measured progression-free survival (PFS), overall (OS), transformation rate,...