A5101760538- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Gastrointestinal Tumor Research and Treatment
- Vitamin D Research Studies
- Gastrointestinal disorders and treatments
- Heart Rate Variability and Autonomic Control
- Vagus Nerve Stimulation Research
- Helicobacter pylori-related gastroenterology studies
- Pancreatitis Pathology and Treatment
- Stress Responses and Cortisol
- Galectins and Cancer Biology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
- Microscopic Colitis
- Epigenetics and DNA Methylation
- IgG4-Related and Inflammatory Diseases
- Case Reports on Hematomas
- Image Enhancement Techniques
- Metastasis and carcinoma case studies
- RNA modifications and cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Renal and related cancers
- Lipid metabolism and biosynthesis
- Kidney Stones and Urolithiasis Treatments
First Affiliated Hospital Zhejiang University
2015-2024
Zhejiang University
2013-2024
International Paper (United States)
2017
University Gastroenterology
2016
Xi'an Jiaotong University
2002
Abstract Background Vitamin D receptor ( VDR ) is a member of the nuclear family transcription factors that play critical role in innate immunity. This study examined gastric immune defence against pathogen H elicobacter pylori . Materials and Methods Seventeen ‐infected patients sixteen controls participated study. The GES ‐1 cells were transfected with si RNA or incubated without 1α,25(OH) 2 3 (100 nmol/L) then infected , cathelicidin antimicrobial protein CAMP ), cytokine m expression...
The aim of the study was to evaluate diagnostic and therapeutic value double-balloon entoroscopy (DBE) in small bowel diseases (SBDs) China.A retrospective review 674 consecutive patients who underwent DBE between January 2007 November 2015 conducted. Patients were divided into 3 groups by age, young group (<45 years), middle-aged (45-65 elderly (>65 years). Data collected with regard demographics, clinical, endoscopic findings, complications, yield, management.A total 729 procedures...
Abstract Background Ulcerative colitis [UC] is a common chronic inflammatory bowel disease without curative treatment. Methods We conducted gene set enrichment analysis to explore potential therapeutic agents for UC. Human colon tissue samples were collected test H3 acetylation in Both vivo and vitro models constructed verify the role mechanism of modification Intestine-specific vitamin D receptor [VDR]-/- mice VD [vitamin D]-deficient diet-fed used downstream molecular mechanisms...
The aim of the current study was to enhance awareness phlebosclerotic colitis (PC) through our clinical experience.A retrospective review 25 patients who were diagnosed as PC in 2 affiliated hospitals from January 2013 October 2017 conducted.The found at a mean age 63.5 years, range 47 87years. majority male (23 cases). Only 4 (16%, 4/25) had history about long-term use Chinese herbs and medical liquor. most common symptoms abdominal pain (40%) intestinal obstruction (16%), followed by...
Abstract Ulcerative colitis (UC) is a common inflammatory bowel disease (IBD) producingintestinal inflammation and tissue damage. The precise aetiology of UC remainsunknown. In this study, we applied rank-based expression profile comparativealgorithm, gene set enrichment analysis (GSEA), to evaluate the profilesof patients small interfering RNA (siRNA)-perturbed cells predict proteinsthat might be essential in from publicly available profiles. We usedquantitative PCR (qPCR) characterize...
Nonalcoholic fatty liver disease (NAFLD) is increasingly regarded as a hepatic manifestation of metabolic syndrome. Though with high prevalence, the mechanism poorly understood. This study aimed to investigate effects p21 on free acid (FFA)-induced steatosis in L02 cells. We therefore analyzed cells MG132 and siRNA treatment for different expression related lipid accumulation lipotoxicity. Cellular total was stained by Oil Red O, while triglyceride content, cytotoxicity assays, peroxidation...
Gastric metastasis from renal cell carcinoma (RCC) is an extremely rare clinical entity. Due to easily neglected RCC history, nonspecific symptoms and under-recognized endoscopic presentation may lead a potential diagnostic pitfall in daily practice.We present case of metastatic gastric tumors arising 5 years after radical nephrectomy. Simultaneous, multifocal metastases the gallbladder, pancreas soft tissue were observed. One year previously, solitary submucosal discoid tumor with central...
BACKGROUND Extragastric lesions are typically not misdiagnosed as gastric submucosal tumor (SMT). However, we encountered two rare cases where extrinsic were SMTs. CASE SUMMARY We describe of SMT-like protrusions initially SMTs by the abdominal contrast-enhanced computed tomography (CT) and endoscopic ultrasound (EUS). Based on CT EUS findings, patients underwent gastroscopy; however, no was identified after incising wall. Subsequent surgical exploration revealed in both patients, but a mass...
Hematoma arising within an intrapancreatic accessory spleen (IPAS) is extremely rare pathological entity.We present the case of a 39-year-old man with acute abdominal pain.The patient was initially diagnosed as pancreatic cystic neoplasm according to CT and MRI imaging.Distal pancreatectomy conducted because possibility malignancy.Surgical resection showed that lesion hematoma in IPAS.Our indicated differential diagnosis IPAS should be born mind for cases tail pancreas epidermoid cyst (ECIAS).
Psychological stress has been proved to be a risk factor for exacerbation ulcerative colitis (UC). However, traditional approaches of quantifying psychological using scales are time-consuming and the results may not comparable among patients with different educational levels cultural backgrounds. Alternatively, heart rate variability (HRV) is an indicator biased by backgrounds.In this study, we try explore relationship between UC analyzing effect ultra-short-term HRV on mucosal histological...
Colorectal cavernous hemangioma is a rare vascular malformation resulting in recurrent lower gastrointestinal hemorrhage, and can be misinterpreted as colitis. Surgical resection currently the mainstay of treatment, with an emphasis on sphincter preservation.
Introducción: la betatrofina es una novedosa adipoquina que provoca proliferación de células β pancreáticas e interviene en el metabolismo los lípidos. Objetivos: propósito este estudio evaluar papel síndrome metabólico. Método: se llevó a cabo un hospitalario casos y controles según sexo edad. El nivel suero fue evaluado mediante ensayo por inmunoabsorción ligado enzimas. Se midieron las concentraciones 12 adipoquinas para asociaciones con usando kits comerciales Adipokine Magnetic Bead...
Abstract Background Psychological stress has been proved to be a risk factor for exacerbation ulcerative colitis (UC). However, traditional approaches of quantifying psychological using scales are time-consuming and the results may not comparable among patients with different educational levels cultural backgrounds. Alternatively, heart rate variability (HRV) is an indicator biased by Aims In this study, we try explore relationship between UC analyzing effect ultra-short-term HRV on mucosal...
The theories of least-squares estimation and nonlinear function fitting are applied to solve the problem data smoothing in image processing. Based on derived algorithm, a novel spatial-domain template with variable mask size is obtained. It can preserve important information digital images as it smooths. Experimental results detailed case studies have shown that has advantages over commonly adopted filtering masks. quality resulting very good, even under strongly noise-corrupted conditions.<...