A5101663902- Intracranial Aneurysms: Treatment and Complications
- Medical Imaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Neurological Complications and Syndromes
- Acute Ischemic Stroke Management
- Organ and Tissue Transplantation Research
- Moyamoya disease diagnosis and treatment
- Neuroblastoma Research and Treatments
- Transplantation: Methods and Outcomes
- Organ Donation and Transplantation
- Glioma Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Radiopharmaceutical Chemistry and Applications
- Gastric Cancer Management and Outcomes
- Blood Pressure and Hypertension Studies
- Nutritional Studies and Diet
- Peptidase Inhibition and Analysis
- Neuroendocrine Tumor Research Advances
- Renal and Vascular Pathologies
- Cardiac Imaging and Diagnostics
- Health Promotion and Cardiovascular Prevention
- Brain Metastases and Treatment
- Gastrointestinal Tumor Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
Capital Medical University
2017-2025
Beijing Friendship Hospital
2023-2025
National Natural Science Foundation of China
2024
Northern Jiangsu People's Hospital
2022-2024
Nanjing University
2024
Ningbo University of Technology
2023
Capital University
2017-2022
Beijing Anzhen Hospital
2017-2022
Medical University of Vienna
2022
Guangdong Pharmaceutical University
2015-2021
Renal ischemia reperfusion injury leads to acute kidney (AKI) and is associated with tissue edema, inflammatory cell infiltration, subsequent development of interstitial renal fibrosis tubular atrophy. The purpose this study was investigate the value functional magnetic resonance imaging (MRI) techniques, T2 mapping, diffusion-weighted (DWI) in characterizing chronic pathology after unilateral AKI mice.Moderate or severe AKIs were induced C57Bl/6 mice through transient clamping pedicle for...
The expression of chemokine receptor type 4 (CXCR4) was found co-localized with macrophages on the atherosclerotic vessel wall and participated in initial emigration leukocytes. Gallium-68 [68Ga]Pentixafor has recently been introduced for imaging atherosclerosis by targeting CXCR4. We sought to evaluate human lesions using PET/MRI.Thirty-eight oncology patients underwent PET/MR at baseline. Maximum standardized uptake values (SUVmax) were derived from hot seven arterial segments...
Type 4 chemokine receptor (CXCR4) plays an important role in immune cell migration during the atherosclerosis progression. We aimed to evaluate [68Ga]Pentixafor positron emission tomography (PET) combination magnetic resonance imaging (MRI) for vivo quantification of CXCR4 expression carotid plaques.Seventy-two patients with lymphoma were prospectively scheduled whole body PET/MRI additional T2-weighted sequence. Volumes interest (VOIs) drawn along bifurcation regions, and maximum...
Abstract A 10-year-old girl with high-risk neuroblastoma underwent 123 I-MIBG SPECT/CT and 68 Ga-DOTATE PET/CT, which both showed multiple bone metastases. However, following 177 Lu-DOTATATE therapy, only Ga-DOTATATE PET/CT identified residual lesions negative results. The case emphasized the complementary role of after therapy.
Abstract A 2-year-old girl with history of high-risk neuroblastoma underwent 123 I-MIBG, which showed increased I-MIBG in the left side head. Contrast-enhanced MRI and cerebral spine fluid cytology confirmed diagnosis leptomeningeal metastasis.
Abstract A 7-year-old boy with high-risk neuroblastoma underwent 123 I-MIBG SPECT/CT to evaluate the therapy response. The scan revealed abnormal uptake in left basal ganglion, indicating possibility of brain metastasis. Subsequent contrast-enhanced MRI, however, did not show any signal intensity ganglion. Follow-up scans at 3-month and 9-month also MIBG same area. case highlights false-positive
Abstract An 8-year-old girl with refractory high-risk neuroblastoma underwent 68 Ga-DOTATATE PET/CT to evaluate the feasibility of potential 177 Lu-DOTATATE therapy. The scan showed multiple foci abnormal accumulation in bone region, indicating presence metastases. Unexpectedly, an tracer uptake was noted left lateral ventricle area. contrast-enhanced brain MRI obvious enhancement this lesion, suggesting diagnosis choroid plexus metastasis. Our case shows that might be useful diagnosing
An 8-year-old boy with high-risk neuroblastoma underwent routine follow-up 123I-MIBG scan, which revealed abnormal accumulation in right pleura, suggestive of potential metastasis. Histopathologic examination the biopsy specimen confirmed presence pleural The patient subsequently received four cycles chemotherapy. A scan after chemotherapy demonstrated no MIBG uptake, indicating remission However, 6 months later, a subsequent recurrent uptake pleura at same location as initial recurrence....
To determine the factors affecting in-hospital prognosis of patients with acute ST segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI), and to establish its prognostic discriminant model. A total 701 consecutive STEMI undergoing PCI were enrolled in this study. The divided into two groups, good poor prognosis, based on whether patient had adverse outcomes (death or heart function ≥ grade III) at discharge. Demographic basic clinical characteristics,...
(1) This study compared [68Ga]PentixaFor uptake in active arterial segments with corresponding [18F]FDG as well the relationship cardiac uptake. (2) Method: Tracer on atherosclerotic lesions large arteries was measured and target-to-background ratios (TBR) were calculated to adjust background signals two investigators blinded other PET scan. On a patient-based lesion-to-lesion analysis, TBR values of tracers inflammation further explored. Furthermore, cardiovascular risk-related groups...
The aim was to determine the burden of diabetes mellitus (DM) in an urban area China aid us planning preventive measures for those at risk DM. A survey conducted among 29 859 subjects aged between 30 and 64 belonging 32 units Shougang Corporation (a heavy industry enterprise) within Beijing area. WHO study protocols diagnostic criteria were used prevalence DM impaired glucose tolerance (IGT). results showed that age-adjusted prevalance (IGT) 3.63 % 4.19 %, respectively, both increasing with...
Epidermal growth factor (EGF) plays an important role in the regulation of gastrointestinal tissue and development, it can stimulate epithelial proliferation, cell differentiation growth. It has been established that EGF promote gastric cytoprotection ulcer healing. But potential ability to regulate cancer is unknown. This study investigate influence on human implanted tumor nude mice.The rates adenocarcinoma lines MKN-28, MKN-45, SGC-7901 normal cells 3T3 were assessed when incubated with...
Baroreflex is critical to maintain blood pressure homeostasis, and the quantification of baroreflex regulation function (BRF) can provide guidance for disease diagnosis, treatment, healthcare. Current BRF such as sensitivity cannot represent systematically. From perspective complex systems, we regard that emergence result fluctuate states interactions in physiological mechanisms. Therefore, three‐layer studied this work, which from mechanisms indexes then BRF. On basis, since entropy...
Abstract A translocator protein 18 kDa targeted radiotracer, N,N -diethyl-2-(2-(4-[ F]fluorophenyl)-5,7-dimethylpyrazolo[1,5-a] pyrimidin-3-yl) acetamide ([ F]FDPA), was automated synthetized and evaluated for cardiac inflammation imaging. Various reaction conditions an synthesis were systematically optimized. MicroPET/CT imaging performed on normal rats with myocardial infarction (MI). Normalized SUV ratios of [ F]FDPA to 13 N]NH 3 (NSRs) in different regions calculated normalize the uptake...
Objective: Hybrid recanalization for vertebral artery (VA) long-segmental occlusion using a combination of ostial endarterectomy and distal endovascular stenting has achieved technical success. The safety efficacy the hybrid technique should be further evaluated. Methods: We examined cohort refractory patients with in VA low flow basilar (BA). was performed to achieve VA. Angiograms were analyzed occlusive length, contralateral status collaterals. Clinical variables, including 30-days...