A5018188264- Ion Channels and Receptors
- Cardiac Fibrosis and Remodeling
- Traditional Chinese Medicine Analysis
- Inflammatory mediators and NSAID effects
- Magnesium in Health and Disease
- Metabolomics and Mass Spectrometry Studies
- Sirtuins and Resveratrol in Medicine
- Autophagy in Disease and Therapy
- Nutrition and Health in Aging
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- BRCA gene mutations in cancer
- Moyamoya disease diagnosis and treatment
- PARP inhibition in cancer therapy
- Protein purification and stability
- Gut microbiota and health
- Pulmonary Hypertension Research and Treatments
- Mitochondrial Function and Pathology
- Cardiac electrophysiology and arrhythmias
- Magnesium Alloys: Properties and Applications
- Nanoparticle-Based Drug Delivery
- Glutathione Transferases and Polymorphisms
- Calcium Carbonate Crystallization and Inhibition
- Peptidase Inhibition and Analysis
- Cardiovascular Issues in Pregnancy
Guangdong Academy of Medical Sciences
2016-2023
Southern Medical University
2023
Guangdong Provincial People's Hospital
2023
Guangdong General Hospital
2016-2018
Sun Yat-sen University
2013-2018
Capital Medical University
2012
Introduction: There is growing evidence of research indicating that the gut microbiota involved in development sarcopenia. Nevertheless, there exists a notable deficiency comprehension concerning connection between irregularities intestinal microbiome and metabolic processes older individuals suffering from Methods: To analyze fecal samples obtained cohort 30 patients diagnosed with sarcopenia as well without sarcopenia, this study employed 16S rDNA sequencing liquid chromatography-mass...
Cryptotanshinone (CTS), a bioactive constituent extracted from Chinese traditional herb Danshen (Salvia miltiorrhiza), demonstrates multiple protective effects against cardiovascular diseases. The present study was designed to explore the of CTS in vitro by cultured adult rat cardiac fibroblasts stimulated with angiotensin II (Ang II) and vivo rats acute myocardial infarction. Our data showed that fibroblasts, attenuated Ang II-induced upregulation fibronectin, connective tissue growth...
Store-operated Ca2+ entry (SOCE) is an important mechanism of extracellular into cells. It has been proved that SOCE involved in many pathologic and physiological processes. Two key participants SOCE, stromal interaction molecule1 (STIM1) Orai1, have identified. But their function cardiac fibroblasts remains elusive. In present study, our findings suggested the expression STIM1 Orai1 were increased followed by angiotensin II (Ang II) stimulation vivo vitro. cultured adult rat fibroblasts,...
Prostaglandin E2 (PGE2), one of the arachidonic acid metabolites synthetized from through cyclooxygenase (COX) catalysis, demonstrates multiple physiological and pathological actions different subtypes EP receptors.The present study was designed to explore effects PGE2 on cardiac fibrosis involved mechanism.We used western blot analysis, real-time quantitative PCR immunostaining etc. testify mechanism.Our data showed that in cultured adult rat fibroblasts (CFs), effectively promoted...