A5077724465- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Enhanced Recovery After Surgery
- Colorectal and Anal Carcinomas
- Radiation Dose and Imaging
- Inflammatory Biomarkers in Disease Prognosis
- Aortic aneurysm repair treatments
- Surgical site infection prevention
- Surgical Sutures and Adhesives
- Trauma Management and Diagnosis
- Diverticular Disease and Complications
- Hernia repair and management
- Hemostasis and retained surgical items
- Pleural and Pulmonary Diseases
Erasmus MC Cancer Institute
2024
Erasmus MC
2013-2022
Erasmus University Rotterdam
2019-2022
Dutch Institute for Clinical Auditing
2018
Anastomotic leakage remains a major complication after surgery for colorectal carcinoma, but its origin is still unknown. Our hypothesis was that early anastomotic mostly related to technical failure of the anastomosis, and late healing deficiencies.The aim this study assess differences in risk factors leakage.This retrospective cohort study.The Dutch ColoRectal Audit nationwide project collects information on all patients undergoing cancer.All surgical resection cancer Netherlands between...
Abstract Aim Anastomotic leakage (AL) is one of the most feared complications after rectal resection. This study aimed to assess a combination biomarkers for early detection AL cancer Method was an international multicentre prospective cohort study. All patients received pelvic drain On first three postoperative days fluid collected daily and C‐reactive protein (CRP) measured. Matrix metalloproteinase‐2 (MMP2), MMP9, glucose, lactate, interleukin 1‐beta (IL1β), IL6, IL10, tumour necrosis...
Background The aim of this study was to investigate the effect age on CAL and its associated mortality. Methods Data were derived from Dutch ColoRectal Audit. All patients undergoing resection for colorectal cancer in Netherlands between January 2011 December 2016 included. Univariable multivariable logistic regressions performed test Results In total, 45 488 incidence 6.4% <60 years old, 5.5% 60‐69 5.4% 70‐80 4.9% ≥80 old ( P < 0.001). Multivariate analysis showed that protective (OR...
This study aimed to identify whether CRP-trajectory measurement, including increase in CRP-level of 50 mg/l per day, is an accurate predictor anastomotic leakage (AL) patients undergoing resection for rectal cancer.A prospective multicentre database was used. CRP recorded on the first three postoperative days. Sensitivity, specificity, positive and negative predictive values, area under receiver operator characteristic (ROC) curve were used analyse performances measurements between day (POD)...
This subgroup analysis of a prospective multicentre cohort study aims to compare postoperative morbidity between transanal total mesorectal excision (TaTME) and laparoscopic (LaTME).The was designed as study. Patients undergoing TaTME or LaTME for rectal cancer were selected. All patients followed up until the first visit outpatient clinic after hospital discharge. Postoperative complications classified according Clavien-Dindo classification comprehensive complication index (CCI). Propensity...
Tumor resection is the common approach in patients with colorectal malignancy. Profound insight into inflammatory changes that accompany normal post-operative stress response will establish reference parameters useful for identification of putative complications. Alterations circulating monocytes might be indicative as these cells are considered to most responsive leukocytes trauma. Therefore, aim this study assess monocyte subset kinetic and phenotypic surgery. Fifty undergoing tumor were...
Reconstruction of full thickness chest wall defects is challenging and associated with a considerable risk complications. Therefore, the aim this study was to investigate surgical outcomes their associations patient treatment characteristics following reconstruction.
Background. Improved patient outcomes after colorectal surgery in high-volume hospitals are leading to centralization of surgery. However, it is desirable strive for optimal quality low-volume hospitals. This study aimed assess the effect number surgeons involved surgical procedure on a hospital. Methods. All patients who underwent elective with construction primary anastomosis between January 1, 2007, and December 31, 2015, were included this retrospective cohort. The propensity score was...