A5103092135- Cardiovascular Disease and Adiposity
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Growth Hormone and Insulin-like Growth Factors
- Venous Thromboembolism Diagnosis and Management
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 detection and testing
- Diabetes and associated disorders
- Neuroendocrine Tumor Research Advances
- Lipid metabolism and disorders
- Infectious Diseases and Tuberculosis
- SARS-CoV-2 and COVID-19 Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nuclear Structure and Function
- Ethics and Social Impacts of AI
- Blood donation and transfusion practices
- Otolaryngology and Infectious Diseases
- Fetal and Pediatric Neurological Disorders
- Fibroblast Growth Factor Research
- Systemic Sclerosis and Related Diseases
- Hate Speech and Cyberbullying Detection
- Boron Compounds in Chemistry
- Bone health and treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Chronic Obstructive Pulmonary Disease (COPD) Research
Indian Institute of Technology Dhanbad
2025
Government Medical College
2024
National Institute of Technology Kurukshetra
2024
Sawai ManSingh Medical College and Hospital
2016-2021
Rajendra Institute of Medical Sciences
2021
Lehigh Valley Hospital-Pocono
2014-2015
Health Net
2015
Lehigh Valley Hospital
2013
The rapid emergence of coronavirus disease 2019 (COVID-19) as a global pandemic affecting millions individuals globally has necessitated sensitive and high-throughput approaches for the diagnosis, surveillance, determining genetic epidemiology SARS-CoV-2. In present study, we used COVIDSeq protocol, which involves multiplex-PCR, barcoding, sequencing samples detection deciphering We approach on 752 clinical in duplicates, amounting to total 1536 could be sequenced single S4 flow cell NovaSeq...
Abstract The rapid emergence of coronavirus disease 2019 (COVID-19) as a global pandemic affecting millions individuals globally has necessitated sensitive and high-throughput approaches for the diagnosis, surveillance determining genetic epidemiology SARS-CoV-2. In present study, we used COVIDSeq protocol, which involves multiplex-PCR, barcoding sequencing samples detection deciphering We approach on 752 clinical in duplicates, amounting to total 1536 could be sequenced single S4 flow cell...
Systemic sclerosis (also called scleroderma, SSc) is a chronic autoimmune fibrotic disorder affecting the skin and internal organs to variable extent categorized as limited cutaneous subset, when distal areas of are involved diffuse subset more extensive proximal involvement seen. Multiple pathogenic mechanisms have been demonstrated, including production disease-specific autoantibodies, infiltration tissues by immune cells, well environmental factors triggering onset such solvents viruses....
Abstract: Therapidgrowthoftechnologiesnotonly formulates life easier but also exposes a lotof securityissues. With the advancement of theInternetoveryears,thenumberofattacks overtheInternethasbeenincreased.Intrusion Detection System (IDS )isoneofthesupportive layers applicable to information security. IDS provideasalubriousenvironmentforbusiness and keeps away from suspicious network activities. Recently, Machine Learning (ML) algorithmsareappliedinIDSinorderto identify classify security...
Type 2 diabetes (T2D) is a complex disease with an elusive link between its molecular aetiology and clinical presentation. Although, the role of visceral adipose tissue in insulin-resistance T2D known, limited information available on peripheral-subcutaneous especially Asian Indians. In this microarray-based study diabetic normal glucose tolerant Indians, we generated transcriptome their thigh analyzed differentially expressed genes (DEGs) using weighted gene co-expression network analysis;...
The roles of abdominal visceral (VAT) and subcutaneous adipose tissue (SAT) in the molecular pathogenesis type-2 diabetics (T2D) among Asian Indians showing a “thin fat” phenotype largely remains obscure. In this study, we generated transcription profiles biopsies these depots obtained during surgery 19 (M: F ratio, 8:11) 16 ratio 5:11) age- BMI-matched non-diabetics. Gene set enrichment analysis (GSEA) was used for comparing profile showed that gene sets, enriching inflammation immune...
The pathogenic mechanisms causing type 2 diabetes (T2D) are still poorly understood; a greater awareness of its causation can lead to the development newer and better antidiabetic drugs. In this study, we used network-based approach assess cellular processes associated with protein–protein interaction subnetworks glycemic traits—HOMA-β HOMA-IR. Their were further analyzed in terms their overlap differentially expressed genes (DEGs) pancreatic, muscle, adipose tissue diabetics. We found...
T2D is a complex disease with poorly understood mechanisms. In Asian Indians, it associated "thin fat" phenotype which resembles partial lipodystrophy. We hypothesized that disturbed expression of lipodystrophy genes might play role in pathogenesis. Therefore, we attempted to establish link between these two diseases by studying the overlap network and differentially expressed (DEGs) peripheral subcutaneous adipose tissue Indians diabetics. found 16, out 138 were regulated diabetics around...
Congenital idiopathic growth hormone deficiency (GHD) is associated with various MRI abnormalities, including sellar and extrasellar abnormalities. However, it remains contentious whether brain findings could provide an additional avenue for precisely predicting the differentiation of GHD based on severity type {isolated or multiple pituitary deficiencies (MPHD)}. This study aimed to ascertain abnormality that best predictor amongst different findings.We conducted analytical cross-sectional...
In conclusion, we report 6 patients with asymptomatic peritoneal leukocytosis and sterile effluent post-exteriorization of buried PD catheters.The pathophysiology this phenomenon is not clear.We recommend that persistent cloudy a catheter be empirically treated for peritonitis, but if are cultures return negative, then our data suggest antibiotics may safely stopped.
Acute suppurative thyroiditis (AST) leading to thyroid abscess is a quite uncommon clinical entity. Both and AST represent only 0.1%–0.7% of pathologies which may require surgical management. especially affects patients with Hashimoto's or cancer. In children, associated the persistence canal originating from 3rd 4th bronchial pouch that lead recurrent abscess. The left lobe gland more frequently involved. can be life threatening if untreated, resulting in mortality 12% higher.
Idiopathic hypogonadotropic hypogonadism (IHH) can be associated with anosmia/hyposmia. The objective of this study is to evaluate olfaction by Indian smell identification test (INSIT) and measure olfactory bulbs (OBs) sulci using dedicated magnetic resonance imaging (MRI) in patients IHH correlate MRI findings INSIT.Forty underwent (a) brief (b) the apparatus. size sulcus bulb was quantified compared normative data obtained 22 controls. agreement between INSIT assessed Kappa index.Of 40...
Efficacy of bilateral inferior petrosal sinus sampling (BIPSS) in corticotropin-dependent Cushing's syndrome (CS) for localization and lateralization excess adrenocorticotropic hormone (ACTH) source, as compared to high-dose dexamethasone suppression test (HDDST) magnetic resonance imaging (MRI) pituitary, respectively.Thirteen patients with clinically biochemically confirmed CS underwent HDDST, MRI BIPSS by an experienced team intervention neurologist, neurosurgeon, endocrinologist using...
Iliopsoas abscess (IPA) is a collection of pus in the iliopsoas compartment which an extraperitoneal space proximity to various gastrointestinal organs, spine, aorta, and kidney. The most common cause IPA hematogenous spread from distant sites. Percutaneous drainage antitubercular treatment are successful majority patients rarely requiring operative intervention. We present case 65-year-old Asian man, tobacco chewer who presented emergency with long-standing history swelling at previous site...
Osteoporosis and fragility fractures are a major public health issue. Secondary osteoporosis is characterised by the presence of an underlying disease, deficiency, or use drug. Conditions that increase speculation for secondary include amongst younger men premenopausal women, markedly decreased Bone Mineral Density (BMD) values, despite conforming to anti-osteoporotic therapy. Since emphasis on treatment primary disorder, diagnosis thus opportunity preventive intervention can be missed. With...
Mean platelet volume is a marker of inflammation which found to be increased in patients at risk for atherothrombotic disease and measurement has been suggested as activation 1 .The association between Volume chronic obstructive pulmonary controversial Objective: To determine the difference mean with Chronic Obstructive Pulmonary Disease healthy age matched controls Method: This study was conducted Department Medicine, SMS Medical College Attached hospitals, Jaipur.55 Patients COPD diagnosed...