A5101308649- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Cancer, Lipids, and Metabolism
- Gastric Cancer Management and Outcomes
- RNA modifications and cancer
- Lung Cancer Treatments and Mutations
- Metastasis and carcinoma case studies
- Cancer, Hypoxia, and Metabolism
- Esophageal and GI Pathology
- Cancer survivorship and care
- High Entropy Alloys Studies
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Cancer-related cognitive impairment studies
- Medical Imaging and Pathology Studies
- Additive Manufacturing Materials and Processes
- Hemostasis and retained surgical items
- Cancer Genomics and Diagnostics
- Burn Injury Management and Outcomes
- Advanced Materials Characterization Techniques
- Neuroendocrine Tumor Research Advances
- MRI in cancer diagnosis
- Ultrasound and Hyperthermia Applications
- Thermoregulation and physiological responses
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Second Affiliated Hospital of Zhejiang University
2025
Zhejiang University
2017-2024
First Affiliated Hospital Zhejiang University
2017-2024
Kunming Medical University
2023
Second Affiliated Hospital of Kunming Medical College
2023
Shenzhen University
2023
Shantou University
2023
Shantou University Medical College
2023
Shenzhen International Travel Health Care Center
2012
Abstract Acute Kidney Injury (AKI) is a significant medical condition characterized by the abrupt decline in kidney function.Low‐intensity pulsed ultrasound (LIPUS), non‐invasive therapeutic technique employing low‐intensity acoustic wave pulses, has shown promise promoting tissue repair and regeneration. A novel LIPUS system was developed evaluated rat AKI models, focusing on its effects glomerular filtration rate (GFR), blood urea nitrogen (BUN), serum creatinine (SCr), Notch1‐Akt‐eNOS...
Abstract High tumor mutation burden (TMB), which is associated with increased immunogenicity, has been identified to predict improved response immune checkpoint inhibitors (ICIs) therapy in non-small cell lung cancer (NSCLC). As host immunity also significant eliminate cells, however, its clinical impact on immunotherapy still largely unknown. Here we explored the influence of age, an important characteristic evaluate patients, TMB-based predictive system for ICIs NSCLC. Our results showed...
The prognostic performance of different lymph node staging schemes for adenocarcinoma esophagogastric junction (AEG) remains controversial. objective the present study was to compare efficacy number metastases (LNMs), positive ratio (LNR) and log odds nodes (LODDS). Patients diagnosed with Siewert type II AEG were included from Surveillance, Epidemiology, End Results database. Harrell's C-index statistic, Schemper's proportion explained variation (PEV), Akaike information criterion (AIC)...
Background: Epithelial-mesenchymal transition (EMT) plays an important role in the invasion and migration during cancer metastasis. Wnt3a is one of ligands canonical Wnt/β-catenin signaling pathway, which contributes to carcinogenesis progression lung cell lines. The aim this study was evaluate association between EMT-related proteins (E-cadherin N-cadherin), further investigate its impact on prognosis adenocarcinoma patients. Methods: A total 147 patients were included their...
Pulmonary nodular lymphoid hyperplasia (PNLH) is a rare benign disease lacking systematically clinical assessment. This study aims to explore the features of PNLH and evaluate safety efficacy different surgical approaches for PNLH.Patients with confirmed in our department between March 2007 August 2017 were retrospectively reviewed. The detail information patients, including demographic characteristics, medical history, preoperative investigations, perioperative findings, postoperative...
Abstract Background Esophageal cancer (EC) is a malignant tumor with high mortality. Nomogram an important tool used in clinical prognostic assessment. We aimed to establish novel nomogram predict the overall survival (OS) of EC patients after radical esophagectomy. Methods Data pertaining survival, demography, and clinicopathology 311 who underwent esophagectomy were retrospectively investigated. The was established based on Cox hazard regression analysis. calibration curves Harrell's...
Accurate preoperative lymph node (LN) staging is important for surgical treatments of esophageal squamous cell carcinoma (ESCC). The aim the study was to investigate role nodes assessment by computed tomography (CT) scans in prognostic estimates and dissection strategy.A total 233 stage pN0 ESCC patients who underwent radical esophagectomy from 2009 2016 were included, with last follow-up time 2018. Survival analysis conducted assess relationship between clinical LN metastasis prognosis...
Background: Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive tumor types worldwide, and malnutrition prevails in these patients.However, there no preoperative nutritional assessment tool specifically designed for patients with ESCC.Methods: Patients who received esophagectomy from 2004 to 2016 were consecutively included.The risk factors ESCC screened by univariate multivariate Cox regression analysis construct a new scoring tool.A prognostic model based on was further...
Abstract Background Metabolism is a hallmark of cancer and it involves in resistance to antitumor treatment. Therefore, the purposes this study are classify metabolism-related molecular pattern explore tumor microenvironment characteristics for prognosis predicting prostate cancer. Methods The mRNA expression profiles corresponding clinical information patients from TCGA, cBioPortal, GEO databases. Samples were classified using unsupervised non-negative matrix factorization (NMF) clustering...
Non-small cell lung cancer (NSCLC) patients with extrathoracic metastasis (EM) are a highly heterogeneous cohort. Some of these could benefit from primary tumor surgery. This study aimed to identify potential NSCLC EM suitable for resection and determine the optimal therapeutic strategy.
Background Thoracoscopic safe and effective hemostasis is an important condition for rapid rehabilitation of thoracic surgery. Placing hemostatic materials during surgery a commonly used method in lung cancer laparoscopic Among them, resorbable oxidized cellulose material. This research aims to observe the effect Methods A retrospective analysis 42 patients with thoracoscopic undergoing radical Department Thoracic Surgery, First Affiliated Hospital Zhejiang University School Medicine from...
Abstract Minimally invasive esophagectomy is increasingly performed for esophageal squamous carcinoma, with advantages of improved perioperative outcomes in comparison open esophagectomy. Lymph node dissection one most important prognostic factors, cell carcinoma. It still unknown whether MIE can meet the criteria lymph mediastinum, especially T1 and T2 cancer. Here, we compared between surgery. Methods We retrospectively reviewed clinicopathological data from 147 patients who underwent...
The results of the present study suggest that there was a significant difference in occurrence distant metastasis between RC patients with or without mrEMVI, CRM invasion, regional LN metastasis, and MR peritoneal reflex involvement. And mrEMVI were independent risk factors for rectal cancer. Therefore, MRI can be used to observe status EMVI before surgery, which is helpful formulation individualized treatment plans cancer assessment prognosis.
e20527 Background: Radical resection is preferred for treatment of patients with T1 lung cancer, and patient prognoses could be significantly affected by tumor pathological types. Since the clinical data non-small cell cancer (NSCLC) small (SCLC) were rarely reported, real-world study was proposed to explore characteristics target population in practice. Methods: The conducted based on a national collaborative database (designed LinkDoc Technology Co, Ltd.). pathologically diagnosed NSCLC...
e20016 Background: Accurate lymph node assessment is crucial for clinical patient management and prognostic prediction. However, the procedures may not always be performed preoperatively due to time, cost or risk of procedure itself. Present study aimed investigate real world practice preoperative N staging in surgically resected pathologic T1 lung cancer patients China. Methods: This a multicenter retrospective study. Real data on was retrieved from electronic medical records 10 thoracic...