A5100599970- Vietnamese History and Culture Studies
- Smoking Behavior and Cessation
- Mosquito-borne diseases and control
- Health disparities and outcomes
- Crystallization and Solubility Studies
- Music History and Culture
- Alzheimer's disease research and treatments
- Viral Infections and Vectors
- Historical Studies and Socio-cultural Analysis
- Historical and Contemporary Political Dynamics
- SARS-CoV-2 and COVID-19 Research
- Injury Epidemiology and Prevention
- Obesity, Physical Activity, Diet
- SARS-CoV-2 detection and testing
- Health Promotion and Cardiovascular Prevention
- Parkinson's Disease Mechanisms and Treatments
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Diverse Musicological Studies
- Korean Peninsula Historical and Political Studies
- Traffic and Road Safety
- Obesity and Health Practices
- Amyotrophic Lateral Sclerosis Research
- Diabetes Management and Education
- Asian Studies and History
Western University
2022-2025
Arthur Rylah Institute for Environmental Research
2025
St Joseph's Health Care
2025
Campbell University
2025
Lawson Health Research Institute
2025
University of Nottingham
2015-2024
Dŵr Cymru Welsh Water (United Kingdom)
2023-2024
London School of Economics and Political Science
2022
Nottingham Biomedical Research Centre
2022
Salford Royal Hospital
2016-2021
West Nile virus (WNV) has caused repeated large-scale human epidemics in North America since it was first detected 1999 and is now the dominant vector-borne disease this continent. Understanding factors that determine intensity of spillover zoonotic pathogen from birds to humans (via mosquitoes) a prerequisite for predicting preventing epidemics. We integrated mosquito feeding behavior with data on population dynamics WNV epidemiology mosquitoes, birds, humans. show Culex pipiens, enzootic...
Heterogeneity in host populations and communities can have large effects on the transmission control of a pathogen. In extreme cases, few individuals give rise to majority secondary infections, which been termed super spreading events. Here, we show that West Nile virus (WNV) is dominated by heterogeneity community, resulting highly inflated reproductive ratios. A single relatively uncommon avian species, American robin ( Turdus migratorius ), appeared be responsible for WNV-infectious...
The COVID-19 pandemic has necessitated a multifaceted rapid response by the scientific community, bringing researchers, health officials, and industry together to address ongoing public emergency. To meet this challenge, participants need an informed approach for working safely with etiological agent, novel human coronavirus SARS-CoV-2. Work infectious SARS-CoV-2 is currently restricted high-containment laboratories, but material can be handled at lower containment level after inactivation....
In addition to exploring why certain states seek develop nuclear weapons (and some choose not pursue such an option), a key question for those interested in proliferation is programmes—despite the aspirations of strong political leaders with apparently ample resources under their command—did succeed, or were stymied, reaching goals. The invasion and occupation Iraq 2003, followed by Muammar Gaddafi's decision at end same year dismantle his mass destruction programmes, provided much new...
Context: The opioid epidemic has included use of traditional drugs and recently newer synthetics. It is critically important to recognize identify these new both clinically through appropriately designed toxicology testing. There little available information on a synthetic gaining popularity, U-47700.Case details: A 23-year-old female presented after using "U4" by nasal insufflation injection. She was cyanotic with respiratory depression responded naloxone in the field. found have non...
Our objective was to compare the clinical and pathological characteristics of frontotemporal dementia patients with MAPT, GRN C9orf72 gene mutations. We carried out a cross-sectional comparative study 74 gene-positive (15 17 42 C9orf72). Thirty had post mortem data permitting clinico-pathological correlation. MAPT were younger than other groups, showed more frequent behavioural disinhibition, repetitive stereotyped behaviours, semantic impairment temporal predominance atrophy. older at death...
Aims To estimate the effectiveness of pregnancy smoking cessation support delivered by short message service (SMS) text and key parameters needed to plan a definitive trial. Design Multi-centre, parallel-group, single-blinded, individual randomized controlled Setting Sixteen antenatal clinics in England. Participants Four hundred seven participants were intervention (n = 203) or usual care 204). Eligible women < 25 weeks gestation, smoked at least one daily cigarette (> 5 pre-pregnancy),...
The feeding behavior of vectors influences the likelihood pathogen invasion and exposure humans to vector-borne zoonotic pathogens. We used multilocus microsatellite genetic typing an introduced mosquito vector DNA sequencing blood meals determine impact hybrid ancestry on emergence West Nile virus (WNV). probability Culex pipiens mosquitoes from two bionomically divergent forms, form molestus pipiens, influenced that they fed but did not explain a late summer shift birds humans. simple...
In this study, we have compared the severity of amyloid plaque formation and cerebral angiopathy (CAA), subtype pattern CAA pathology itself, between APP genetic causes AD (APPdup, mutations), older individuals with Down syndrome (DS) showing Alzheimer's disease (AD) sporadic (early late onset) (sEOAD sLOAD, respectively). The aim was to elucidate important group differences provide mechanistic insights related clinical neuropathological phenotypes. Since lipid cholesterol metabolism is...
During the spring of 2004, approximately 1,950 blood specimens were collected from resident and Nearctic-Neotropical migratory birds on Caribbean islands Puerto Rico Cuba prior to northerly migrations. Eleven seven birds, in Cuba, respectively, showed evidence antibody a flavivirus enzyme-linked immunosorbent assay. Confirmatory plaque-reduction neutralization test results indicated neutralizing antibodies West Nile virus non-migratory which local transmission.
The high pH region of the phase diagram lysozyme with NaCl as a precipitant was determined. In this diagram, crystallizes in one two different orthorhombic modifications, low and temperature modifications. solubility modifications measured at temperatures, values, concentrations. Both show similar dependence on solution conditions where increases decreases concentration. transition between determined from curves shown to increase At values close isoelectric point (pH 11), becomes independent
It has been suggested that patients with motor neurone disease (MND) and those MND combined behavioural variant frontotemporal dementia (bvFTD) (ie FTD + MND) or alone might exist on a continuum based commonalities of neuropathology and/or genetic risk. Moreover, it reported both neuronal glial cell tauopathy can accompany the TDP-43 proteinopathy in cognitive changes, may be fundamental to pathogenesis clinical phenotype. In present study, we sought substantiate these latter findings, test...
The United Arab Emirates (UAE) was the first country in Middle East to report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Serosurveys are essential understanding extent of virus transmission. This cross-sectional study aims assess seroprevalence SARS-CoV-2 infection Emirate Abu Dhabi.Between 19 July and 14 August 2020, 4487 households were selected using a random sample stratified by region citizenship head household (UAE citizen or non-citizen). A cluster 40...
Freshwater ecosystems and their biota are under increasing pressure from anthropogenic stressors. In response to declining fish stocks, hatchery stocking programmes widely implemented as core components of restoration management strategies, with positive outcomes for some wild populations. Despite this, remains contentious due potential genetic ecological risks Monitoring evaluation critical ensuring the long-term sustainability populations, but identification stocked individuals...
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are commonly used for managing type 2 diabetes and obesity. These drugs improve glycemic control promote weight loss, but they can cause gastrointestinal side effects such as gastroparesis bowel obstruction, particularly in patients with preexisting GI motility issues. A 55-year-old woman obesity, diabetes, a history of small obstruction developed severe abdominal pain nausea after starting semaglutide. She was diagnosed treated...