- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Bioinformatics and Genomic Networks
- Genetic Associations and Epidemiology
- Statistical Methods in Clinical Trials
- Magnetism in coordination complexes
- Molecular Sensors and Ion Detection
- Synthesis and biological activity
- Nanocluster Synthesis and Applications
- Crystallography and molecular interactions
- Luminescence and Fluorescent Materials
- Metal complexes synthesis and properties
- Advanced biosensing and bioanalysis techniques
- Metabolomics and Mass Spectrometry Studies
- GABA and Rice Research
- Synthesis and Biological Evaluation
- Cholesterol and Lipid Metabolism
- Advanced Nanomaterials in Catalysis
- Chemical Synthesis and Analysis
- Fluorine in Organic Chemistry
- Cyclopropane Reaction Mechanisms
- Catalytic C–H Functionalization Methods
- RNA Research and Splicing
- Covalent Organic Framework Applications
Sanya University
2024-2025
Hainan Provincial Academy of Agricultural Sciences
2024-2025
Stanford University
2024-2025
Palo Alto University
2025
Hezhou University
2015-2024
University of California, San Francisco
2016-2023
Stanford Medicine
2023
Chinese Academy of Agricultural Sciences
2021-2022
Howard Hughes Medical Institute
2016-2021
Hunan University
2015-2021
CRISPR (clustered regularly interspaced short palindromic repeats)-based gene inactivation provides a powerful means for linking genes to particular cellular phenotypes. CRISPR-based screening typically uses large genomic pools of single guide RNAs (sgRNAs). However, this approach is limited phenotypes that can be enriched by chemical selection or FACS sorting. Here, we developed microscopy-based approach, which name optical enrichment, select cells displaying CRISPR-induced phenotype...
The chromosomal theory of inheritance dictates that genes on the same chromosome segregate together while different chromosomes assort independently
Background Using data from the GARFIELD ‐ AF (Global Anticoagulant Registry in FIELD –Atrial Fibrillation), we evaluated impact of chronic kidney disease ( CKD ) stage on clinical outcomes patients with newly diagnosed atrial fibrillation ). Methods and Results is a prospective registry 35 countries, including Asia (China, India, Japan, Singapore, South Korea, Thailand). Consecutive enrolled (2013–2016) were classified no, mild, or moderate‐to‐severe , based National Kidney Foundation's...
The first silver nanocluster with an octahedral template of TeO66– was synthesized as a neutral 36-nucleus nanocluster, and its structure demonstrated using single-crystal X-ray diffraction, Fourier transform infrared spectroscopy, electrospray ionization mass spectrometry, photoelectron spectroscopy. peripheral ligands the cagelike skeleton are CF3COO– tBuC≡C–. During synthesis, arranged formed. effect nature displayed on structural features in comparison 8-nucleus cluster, same synthesis...
A one-dimensional high-nucleus silver polymer (SSc: supercapacitor) was designed by a simple and single-step synthesis.
The first transition-metal-catalyzed direct oxidative synthesis of amides by using dioxygen as an oxygen source has been developed under mild conditions, in which DBU was used the key additive. present methodology, utilizes oxidant and cheap copper salts catalysts, opens up interesting attractive avenue for amide functionality.
Understanding the microbial and chemical diversities, as well what affects these is important for modern manufacturing of traditional fermented foods. In this work, Chinese dark teas (CDTs) that are beverages with relatively high sample diversity were collected. Microbial DNA amplicon sequencing mass spectrometry-based untargeted metabolomics show CDT β diversity, nonvolatile α determined by primary impact factors geography procedures, in particular, latitude pile fermentation after...
In order to study the charge effect on formation of an anion-templated silver cluster, a trivalent tetrahedral anion was incorporated into assembly. A 26-nuclear cluster prepared, and its structure confirmed by single-crystal X-ray diffraction. Also, resulting characterized powder diffraction data. Its light absorption photoluminescent properties were studied solid-state UV diffuse-reflectance fluorescence spectroscopy. Compared with other reported clusters templates, more negative VO43- led...
Advancement of the synthesis and control self-assembly process new high-nucleus silver clusters with desired structures is important for both material sciences many applications. Herein, three clusters, 20-, 22-, 8-nucleus, based on alkynyl ligands were constructed their confirmed by single-crystal X-ray diffraction, powder elemental analyses, Fourier-transform infrared spectroscopy (FT-IR). For first time, trivalent tetrahedron anion AsO43-, as a template, surface ligand Ph2PO2H,...
Properties of pore structure in Metal-organic frameworks (MOFs) play a key role the adsorption target molecules hence are used to improve efficiency MOFs. In this study, we synthesized three MOFs with different hydrophilicity, namely TMU-6(RL1), TMU-21(RL2) and TMU-59. Additionally, studied effect hydrophobicity/hydrophilicity on drug delivery sensing properties. The these was characterized by XPS, BET, XRD, IR TG. DLC DLE TMU-59, were determined (20%, 70%), (18%, 78%) (3.6%, 13.6%),...
Pigmented rice grains are important resources for health and nutritional perspectives. Thus, a thorough dissection of the variation nutrients bioactive metabolites in different colored is global interest. This study applied LC–MS-based widely targeted metabolite profiling unraveled variability nutraceuticals long grain/non-glutinous black (BR), red (RR), green (GR), white (WR) grains. We identified classified 1292 metabolites, including five flavonoid compounds specific to BR. The profiles...