A5002571705- Heart Failure Treatment and Management
- Cardiovascular and exercise physiology
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Heart Rate Variability and Autonomic Control
- Trypanosoma species research and implications
- Eosinophilic Disorders and Syndromes
- Cardiomyopathy and Myosin Studies
- Healthcare Regulation
- Blood Pressure and Hypertension Studies
- Atrial Fibrillation Management and Outcomes
- Public Health in Brazil
- Sports Performance and Training
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Health Systems, Economic Evaluations, Quality of Life
- Infective Endocarditis Diagnosis and Management
- Nutrition and Health in Aging
- Erythropoietin and Anemia Treatment
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Cardiac Health and Mental Health
Universidade de São Paulo
2010-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2004-2023
Instituto do Coração
1997-2023
Hospital Santa Marcelina
2011-2023
Hospital do Coração
2019-2020
Universidade Estadual de Londrina
1999-2019
Hospital Universitário da Universidade de São Paulo
1986-2018
Universidade do Estado do Rio de Janeiro
2018
University of California, Los Angeles
2004-2012
Centro Universitário das Faculdades Metropolitanas Unidas
1998-2010
Parte 1: Diretriz Brasileira de Insuficiencia Cardiaca Cronica […] e Aguda
Background: Few studies have prospectively and systematically explored the factors that acutely precipitate exacerbation of congestive heart failure (CHF) in patients with left ventricular dysfunction.Knowledge such is important designing measures to prevent deterioration clinical status.The objective this study was describe precipitants associated CHF status enrolled Randomized Evaluation Strategies for Left Ventricular Dysfunction Pilot Study.Methods: We conducted a 2-stage, multicenter,...
The fundamental determinant of the natural history Chagas' disease is cardiac involvement.We studied 104 male patients with congestive heart failure due to estimate survival distribution function and evaluate age, functional class (FC), maximal oxygen consumption (VO2max), ejection fraction (EF) as predictors survival. Statistical evaluation was performed through univariate (Student's t test chi 2 test) multivariate analyses (Cox's regression model). Overall 66% at 1 year, 56% 3 years, 48% 5...
To test the effects of exercise training on sleep and neurovascular control in patients with systolic heart failure without disordered breathing. Prospective interventional study. Cardiac rehabilitation physiology unit laboratory. Twenty-five failure, aged 42 to 70 years, New York Heart Association Functional Class I-III were divided into 1 3 groups: obstructive apnea (n = 8), central 9) no 7). Four months no-training (control) followed by 4 an program (three 60-minute, supervised, sessions...
We studied the effects of a hypocaloric diet (D, n = 24, age: 32.2 ± 1.4 yr, body mass index: 34.7 0.5 kg/m 2 ) and associated with exercise training (D + T, 25, 32.3 1.3 32.9 0.4 on muscle metaboreflex control, sympathetic nerve activity (MSNA, microneurography), blood pressure, forearm flow (plethysmography) levels during handgrip at 10% 30% maximal voluntary contraction in normotensive obese women. An additional 10 women matched by age index were as nonadherent group. D or T significantly...
The purpose of this study was to determine if abnormalities sympathetic neural and vascular control are present in mild and/or severe heart failure (HF) the underlying afferent mechanisms. Patients with HF, age-matched controls were studied. Muscle nerve activity (MSNA) forearm resistance (FVR) nonexercising arm measured during moderate static handgrip. MSNA handgrip higher at baseline throughout exercise HF vs. (peak 67 +/- 3 54 bursts/min, P < 0.0001) (33 0.0001), but change not different...
Introdução A última Diretriz de Insuficiência Cardíaca do Departamento da Sociedade Brasileira Cardiologia (DEIC/SBC) foi finalizada em março 2018. partir então, houve um importante número intervenções terapêuticas e abordagens diagnósticas que surgiram ou se consolidaram na prática clínica internacional pesquisa clínica. Ao lado disso, a pandemia COVID-19 trouxe-nos conhecimento sobre o modelo fisiopatológico agressão miocárdica muitas dúvidas acerca continuidade segurança dos medicamentos...
There is no information about the muscle metaboreflex control in obese individuals. In 40 normotensive women (OW; body mass index 33.5 ± 0.4 kg/m 2 , age 32.4 1.1 yr) and 15 age-matched, lean (LW; 22.7 0.8 34.4 1.4 yr), we measured sympathetic nerve activity (MSNA) forearm blood flow (FBF) nonexercising during static exercise at 10 30% of maximal voluntary contraction (MVC). Baseline MSNA (38 vs. 31 1 bursts/min, P = 0.001) mean pressure were significantly higher OW compared with LW. FBF was...
OBJETIVO: Considerando-se que a duração do exercício físico possa influenciar hipotensão pós-exercício, testamos hipótese de o submáximo mais prolongado provoca queda pressórica maior magnitude e curto.MÉTODOS: Protocolo experimental - 10 indivíduos realizaram duas sessões (25 45min) no cicloergômetro em 50%VO2 pico. controle 12 permaneceram repouso por 45min. A pressão arterial (PA) foi aferida antes (20min) após (90min) ou repouso. RESULTADOS: PA sistólica diminuiu significantemente...
Classe I: Evidências e/ou concordância geral de que o procedimento é benéfico e
Background Using data from the GARFIELD ‐ AF (Global Anticoagulant Registry in FIELD –Atrial Fibrillation), we evaluated impact of chronic kidney disease ( CKD ) stage on clinical outcomes patients with newly diagnosed atrial fibrillation ). Methods and Results is a prospective registry 35 countries, including Asia (China, India, Japan, Singapore, South Korea, Thailand). Consecutive enrolled (2013–2016) were classified no, mild, or moderate‐to‐severe , based National Kidney Foundation's...
Measurement of the insulin-like growth factors (IGFs) and their binding proteins has become commonplace in indirect assessment integrity GH axis. However, relative effect deficiency (GHD) on each component IGF axis merit any one parameter as a diagnostic test have not been defined homogeneous population across all ages. We therefore measured IGF-I, IGF-II, IGF-binding protein-1 (IGFBP-1), IGFBP-2, IGFBP-3, acid labile subunit (ALS) 27 GHD subjects (aged 5–82 yr) from an extended kindred...
Patients who require hospitalization because of decompensated HF represent a group the most seriously ill individuals evolve with high mortality and hospital readmission rates.We sought to evaluate current natural course by analyzing rates in this new era neurohormonal blockage.We followed progress 263 patients mean EF 27.1%, admitted for between January 2005 October 2006. readmitted were only those whose health status precluded discharge after assessment drug treatment Emergency Department....