Intermittent fasting (IF) is an effective strategy to improve cardiometabolic health.The objective of this work examine the effects IF on risk factors and gut microbiota in patients with metabolic syndrome (MS).A randomized clinical trial was conducted at a community health service center.Participants included adults MS, age 30 50 years.Intervention consisted 8 weeks "2-day" modified IF.Cardiometabolic including body composition, oxidative stress, inflammatory cytokines, endothelial function...

Abstract Background As a newly proposed diagnosis, data on the prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) is rare. We aimed to assess and risk factors MAFLD using new definition in contemporary South China population. Methods In this population based, cross sectional study, total 5377 participants aged 30–79 years old were recruited from between 2018 2019. was diagnosed subjects who have both hepatic steatosis disorders according international expert...

Epidemiological studies have demonstrated that high total protein intake was related to type 2 diabetes mellitus (T2DM) risks. However, few considered the impact of dietary pattern.We examined associations between and T2DM in different patterns.We used demographic information adults aged 18-75 years from China Health Nutrition Survey (2009), consisting 4113 women 4580 men. Dietary data collected by using 24-h recalls combined with a food inventory for 3 consecutive days. Cluster analysis...

Preterm infants are susceptible to neonatal sepsis, a syndrome of pro-inflammatory activity, organ damage, and altered metabolism following infection. Given the unique metabolic challenges poor glucose regulatory capacity preterm infants, their intake during infection may have high impact on degree dysregulation damage. Using pig model we previously showed that drastic restriction in supply protects against sepsis via suppression glycolysis-induced inflammation, but results severe...

ABSTRACT This study investigates the metabolic impact of skim milk whey‐derived protein concentrate (SPC) for infant formula, including its heat‐treated (HT‐SPC) and stored (HTS‐SPC) variants, on plasma, urine, gut metabolites newborn piglets, compared to conventional whey (WPC). Preterm piglets were fed formula containing WPC, SPC, HT‐SPC, or HTS‐SPC 5 days. Metabolomic analysis colon content was performed using 1H NMR. Relative SPC mainly affected metabolites, increasing 19 in tyrosine...

Unrefined, refined and refined-deodorized cottonseed oils from pressing or extraction technologies were screened using proton (1H) nuclear magnetic resonance (NMR) spectroscopy gas chromatography-mass spectrometry (GC-MS). GC–MS of derivarized non-derivatized (intact oil) allowed detection nearly 100 compounds. These included fatty acids (FA), linoleic (relative percentage concentration 51–58%), palmitic (21–24%), oleic (18–23%) stearic (1.8–2.2%) in hydrolysed oils, β-sitosterol (31–43%),...

The aim of this study was to determine the effect supplementing dairy goat diets with rapeseed oil and sunflower on performance, milk composition, fatty acid profile, in vitro fermentation kinetics. Nine Danish Landrace goats 42 ± 5 days were allocated three treatment groups for days. Animals received a basal diet, formulated 85:15 forage:concentrate ratio, diet supplemented either or at 4% dry matter. Goat sampled 14, 21, 42. Milk composition similar between treatments. From day 14 42,...

OBJECTIVE The aim of this study was to examine the association circulating retinol-binding protein 4 (RBP4) levels with β-cell function across spectrum glucose tolerance from normal overt type 2 diabetes. RESEARCH DESIGN AND METHODS A total 291 subjects aged 35–60 years (NGT), newly diagnosed impaired fasting or (IFG/IGT), diabetes were screened by a standard 2-h oral test (OGTT) use traditional measures evaluate function. From these participants, 74 recruited for an minimal model test, and...

Summary Preterm infants are susceptible to neonatal sepsis, a syndrome of pro-inflammatory activity, organ damage and altered metabolism following infection. Given the unique metabolic challenges poor glucose regulatory capacity preterm infants, their intake during infection may have high impact on degree dysregulation damage. Using pig model we previously showed that drastic restriction in supply protects against sepsis via suppression glycolysis-induced inflammation, but results severe...

The real-time monitoring and analysis of multicomponent gas have high potential applications in environmental industrial production control. This article introduces a portable fiber-enhanced Raman sensing system equipped with hollow-core anti-resonant fiber, which can significantly enhance the interaction strength between pump light sample. gas-filling device is designed to fill fiber within ten seconds. By measuring spectra common gases, analytical performance for gases demonstrated. At...

Necrotising enterocolitis (NEC) is a microbiome-dependent gut disease in preterm infants early life. Antibiotic treatment common intervention for NEC. How NEC lesions, with or without antibiotics, affect plasma metabolome was explored this study. Formula-fed pigs were used as model human and treated saline, parenteral oral antibiotics (n = 15–17) four days after delivery. Gut tissues collected evaluation of NEC-like lesions metabolomic analysis by proton nuclear magnetic resonance...

Preterm infants are susceptible to neonatal sepsis, a syndrome of pro-inflammatory activity, organ damage and altered metabolism following infection. Given the unique metabolic challenges poor glucose regulatory capacity preterm infants, their intake during infection may have high impact on degree dysregulation damage. Using pig model we previously showed that drastic restriction in supply protects against sepsis via suppression glycolysis-induced inflammation, but results severe...

Preterm infants are susceptible to neonatal sepsis, a syndrome of pro-inflammatory activity, organ damage and altered metabolism following infection. Given the unique metabolic challenges poor glucose regulatory capacity preterm infants, their intake during infection may have high impact on degree dysregulation damage. Using pig model we previously showed that drastic restriction in supply protects against sepsis via suppression glycolysis-induced inflammation, but results severe...

Preterm infants are susceptible to neonatal sepsis, a syndrome of pro-inflammatory activity, organ damage, and altered metabolism following infection. Given the unique metabolic challenges poor glucose regulatory capacity preterm infants, their intake during infection may have high impact on degree dysregulation damage. Using pig model we previously showed that drastic restriction in supply protects against sepsis via suppression glycolysis-induced inflammation, but results severe...

The dietary supplementation of vegetable oils is known to improve the energy density as well milk fatty acid profile; however, impacts on foodome largely unknown. This study investigated effect two different sources unsaturated acids, rapeseed oil and sunflower oil, a feeding supplement from dairy goats. Nine Danish Landrace goats at 42 ± 5 days in were allocated three treatment groups for with animals per group. A control group received basal diet made forage concentrate an 85:15 ratio. On...

Non-invasive detection of unstable angina (UA) patients with different severity coronary lesions remains challenging. This study aimed to identify plasma lipoproteins (LPs) that can be used as potential biomarkers for assessing the lesions, determined by Gensini score (GS), in UA patients. We collected blood from 67 inpatients angiographically normal arteries (NCA) and 230 patients, 155 them lowGS (GS ≤ 25.4) 75 highGS > 25.4), analyzed it using proton nuclear magnetic resonance spectroscopy...

Abstract Introduction Uzbekistan is one of the countries with highest number diet-related chronic diseases, which believed to be associated high animal fat intake. Sheep meat in fats (~ 5% muscle), including saturated and monounsaturated fatty acids, it contains nearly twice higher amounts n-3 polyunsaturated acids conjugated linoleic compared beef. Nevertheless, sheep considered health promoting by locals accounts for around 1/3 red intake country. Objectives The aim this study was apply a...

<p>OBJECTIVE: The aim of this study was to examine the association circulating retinol binding protein 4 (RBP4) levels with β cell function across spectrum glucose tolerance from normal overt type 2 diabetes. RESEARCH DESIGN AND METHODS: A total 291 subjects aged 35-60 (NGT), newly diagnosed impaired fasting or (IFG/IGT) and diabetes were screened by standard 2-h oral test (2-h OGTT) use traditional measures evaluate function. 74 these participants recruited in minimal model assessed...

<p>OBJECTIVE: The aim of this study was to examine the association circulating retinol binding protein 4 (RBP4) levels with β cell function across spectrum glucose tolerance from normal overt type 2 diabetes. RESEARCH DESIGN AND METHODS: A total 291 subjects aged 35-60 (NGT), newly diagnosed impaired fasting or (IFG/IGT) and diabetes were screened by standard 2-h oral test (2-h OGTT) use traditional measures evaluate function. 74 these participants recruited in minimal model assessed...