Vladimir Kushnir
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Pancreatitis Pathology and Treatment
- Gastroesophageal reflux and treatments
- Colorectal Cancer Screening and Detection
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal Tumor Research and Treatment
- Marine and environmental studies
- Bariatric Surgery and Outcomes
- Biliary and Gastrointestinal Fistulas
- Eosinophilic Esophagitis
- Aquatic and Environmental Studies
- Dysphagia Assessment and Management
- Cancer Genomics and Diagnostics
- Oceanographic and Atmospheric Processes
- Helicobacter pylori-related gastroenterology studies
- Tracheal and airway disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Marine and coastal ecosystems
- Anesthesia and Sedative Agents
Washington University in St. Louis
2016-2025
Barnes-Jewish Hospital
2012-2025
University of Kansas
2023
Case Western Reserve University
2023
MetroHealth Medical Center
2023
Methodist Hospital
2023
Reading Hospital
2023
Houston Methodist
2023
Saint Louis University
2023
Jewish Hospital
2016-2020
Dysphagia may develop following antireflux surgery as a consequence of poor esophageal peristaltic reserve. We hypothesized that suboptimal contraction response multiple rapid swallows (MRS) could be associated with chronic transit symptoms surgery.Wet swallow and MRS responses on high-resolution manometry (HRM) were characterized collectively in the body (distal contractile integral (DCI)), individually each smooth muscle segment (S2 S3 amplitudes) 63 patients undergoing 18 healthy...
INTRODUCTION: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) prescribed for weight loss and type 2 diabetes mellitus (T2DM) can delay gastric emptying, but risk factors impact on procedure outcomes remain unclear. METHODS: We compared frequency of residue upper endoscopy in patients a GLP-1RA propensity score-matched controls this retrospective case-control study consecutive undergoing endoscopic procedures over 3.5-year period. GLP-1RAs were not held before endoscopy. The presence was...
Observational data on the impact of on-site cytopathology evaluation (OCE) during endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) pancreatic masses have reported conflicting results. We aimed to compare diagnostic yield malignancy and proportion inadequate specimens between patients undergoing EUS-FNA with without OCE.In this multicenter randomized controlled trial, consecutive solid mass underwent randomization for or OCE. The number FNA passes in OCE+ arm was dictated by...
OBJECTIVES: Although screening colonoscopy is effective in preventing distal colon cancers, effectiveness right-sided cancers less clear. Previous studies have reported that retroflexion the right improves adenoma detection. We aimed to determine whether a second withdrawal from vs. forward view alone leads detection of additional adenomas. METHODS: Patients undergoing or surveillance were invited participate parallel, randomized, controlled trial at two centers. After cecal intubation,...
This joint ASGE-ESGE guideline provides an evidence-based summary and recommendations regarding the role of endoscopic bariatric metabolic therapies (EBMTs) in management obesity. The document was developed using Grading Recommendations, Assessment, Development Evaluation (GRADE) framework. It evaluates efficacy safety EBMT devices procedures that currently have CE mark or FDA-clearance/approval, had been approved within five years development. suggests use EBMTs plus lifestyle modification...
Abstract Background Functional gastrointestinal disorders ( FGID ) patients report poor health‐related quality of life HRQOL and experience high rates psychiatric extraintestinal functional disorder EIFD comorbidity. The independent influence these comorbidities on symptom burden remains unknown. We sought to determine whether with mood or comorbidity have poorer greater GI burdens; the in bowel symptoms. Methods Subjects reported (anxiety, depression, somatization, ), criteria (irritable...
Abstract Backgrounds Endoscopic ultrasound (EUS)-guided placement of lumen-apposing metal stents (LAMSs) has gained popularity for the treatment pancreatic walled-off necrosis (WON). We compared 20-mm and 15-mm LAMSs symptomatic WON in terms clinical success adverse events. Methods conducted a retrospective, case-matched study 306 adults at 22 tertiary centers from 04/2014 to 10/2018. A total 102 patients with who underwent drainage LAMS (cases) 204 (controls) were matched by age, sex,...
Abstract Numerous cell states are known to comprise the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME). However, developmental stemness and co-occurrence of these remain poorly defined. Here, we performed single-cell RNA sequencing (scRNA-seq) on a cohort treatment-naive PDAC time-of-diagnosis endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) samples ( n = 25). We then combined with surgical resection 6) publicly available increase statistical power 80)....