- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatitis Pathology and Treatment
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- COVID-19 Clinical Research Studies
- Biliary and Gastrointestinal Fistulas
- Long-Term Effects of COVID-19
- Genetics and Neurodevelopmental Disorders
- Foreign Body Medical Cases
- Ubiquitin and proteasome pathways
- Autoimmune and Inflammatory Disorders
- Gastrointestinal Tumor Research and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Transplantation Techniques and Outcomes
- Inflammatory Bowel Disease
- DNA Repair Mechanisms
- Gastrointestinal Bleeding Diagnosis and Treatment
- Liver Disease and Transplantation
- Congenital Anomalies and Fetal Surgery
- Thermal Regulation in Medicine
- Computational Drug Discovery Methods
- Pneumothorax, Barotrauma, Emphysema
- Machine Learning in Materials Science
Columbia University Irving Medical Center
2020-2024
University of North Carolina Health Care
2024
University of North Carolina at Chapel Hill
2024
Cornell University
2024
NewYork–Presbyterian Brooklyn Methodist Hospital
2024
Texas Health Dallas
2020-2022
Columbia University
2020
University of Cincinnati
2019
University of Colorado Anschutz Medical Campus
2013-2018
University of Cincinnati Medical Center
2018
Recent studies have suggested that proton pump inhibitor (PPI) use may increase the risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and worsen course COVID-19.1Almario C.V. et al.Am J Gastroenterol. 2020; 115: 1707-1715Crossref PubMed Scopus (146) Google Scholar,2Lee S.W. al.Gut. 2021; 70: 76-84Crossref (145) Scholar This observation is biologically plausible, as gastric acid a well-established line defense against microbial pathogens, including...
EUS-guided radiofrequency ablation (RFA) is an endoscopic procedure and emerging therapeutic option for the treatment of pancreatic tumors.1Kim H.J. Seo D.W. Hassanuddin A. et al.EUS-guided porcine pancreas.Gastrointest Endosc. 2012; 76: 1039-1043Abstract Full Text PDF PubMed Scopus (61) Google Scholar, 2Armellini E. Crinò S. Ballare M. al.Endoscopic ultrasound-guided a neuroendocrine tumor.Endoscopy. 2015; 47: E600-E601Crossref (37) 3Ligresti D. Amata Luca B. small adenocarcinoma: new...
Intraductal papillary mucinous neoplasms (IPMNs) are epithelial treated with surgical resection when appropriate. We present a 79-year-old man jandice refractory to endoscopic stenting. Biliary radiofrequency ablation (RFA) cholangioscopy was used as palliation of obstructive jaundice due mucin-producing pancreatic IPMN fistulous biliary communication. Clinical improvement permitted surgery, and he returned pre-illness status at 17 months. The use in the setting filling defects can guide...
Objectives: Advanced ERCP techniques (AETs) for difficult biliary stones include peroral cholangioscopy (POC) with electrohydraulic/laser lithotripsy (EHL/LL), endoscopic papillary large balloon dilation (EPLBD) and mechanical (ML). We assess the efficacy of AETs.Methods: A retrospective query AETs. Primary outcome: Complete duct clearance. Secondary clearance by technique. Statistical Analysis version 9.3 (SAS Inc., Cary, NC).Results: From 1/00 to 10/12, 349 patients were identified which...
The CMG helicase (CDC45-MCM2-7-GINS) unwinds DNA as a component of eukaryotic replisomes. Replisome (dis)assembly is tightly coordinated with cell cycle progression to ensure genome stability. However, factors that prevent premature unloading and replisome disassembly are poorly described. Since catalyzed by ubiquitination, deubiquitinases (DUBs) represent attractive candidates for safeguarding against untimely deleterious unloading. We combined targeted loss-of-function screen quantitative,...
Introduction: In liver transplant centers, ERCP is a necessary tool in managing post-transplant complications such as strictures and biliary leaks. Post-ERCP pancreatitis (PEP) can be devastating adverse event this fragile patient population. Animal models have demonstrated protective effect of tacrolimus on acute pancreatic inflammation with reduction histologic inflammation, amylase, IL-6 levels. Data human subjects yet to published. OBJECTIVE: Assess the clinical efficacy therapy reducing...
Aim: To compare outcomes by sedation class in community patients undergoing index endoscopic retrograde cholangiopancreatography (ERCP). Methods: Nineteen hundred sixteen consecutive underwent ERCP from May 2005 to 2011. Eight thirty seven were excluded due prior papillary intervention or attempted ERCP. A total of 1079 included. The 981 who gastroenterologist directed (GDS) served as the control population, while 98 received anesthesiologist (ADS) case population. Medical records analyzed...
The risk of solid organ malignancy in patients on anti-TNF therapy has been described. However, new therapies for treatment IBD continue to emerge and safety data regarding use with active is lacking. We describe a case series two at the time initiation ustekinumab therapy. followed these mean 35 weeks both without evidence tumor recurrence or progression are clinically well. 1: A 47-year-old man ALS stricturing ileolonic CD adalimumab presented management his IBD. He known distal ileal...