A5100353564- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- melanin and skin pigmentation
- Metal Forming Simulation Techniques
- Genetic diversity and population structure
- Metallurgy and Material Forming
- Genomic variations and chromosomal abnormalities
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Geotechnical and Geomechanical Engineering
- Circular RNAs in diseases
- Genetic Associations and Epidemiology
- High Altitude and Hypoxia
- Animal Nutrition and Physiology
- Laser and Thermal Forming Techniques
- Mining and Gasification Technologies
- Aluminum Alloy Microstructure Properties
- Magnesium Alloys: Properties and Applications
- Genetic factors in colorectal cancer
- Rock Mechanics and Modeling
- Chromosomal and Genetic Variations
- Plant Molecular Biology Research
- Cancer Genomics and Diagnostics
- Livestock and Poultry Management
- Geomechanics and Mining Engineering
Rice Research Institute
2022-2025
Nanjing Maternity and Child Health Care Hospital
2024-2025
Nanjing Medical University
2024-2025
Guangdong Academy of Agricultural Sciences
2025
Affiliated Eye Hospital of Wenzhou Medical College
2025
Wenzhou Medical University
2014-2025
New Jersey Institute of Technology
2023-2024
Research Institute of Petroleum Exploration and Development
2022-2024
Jiangxi Science and Technology Normal University
2021-2024
Shenyang Agricultural University
2022-2024
The Tibetan pig is one of domestic animals indigenous to the Qinghai-Tibet Plateau. Several geographically isolated populations are distributed throughout It remained an open question if these have experienced different demographic histories and evolved independent adaptive loci for harsh environment To address questions, we herein investigated ~ 40,000 genetic variants across genome in a broad panel 678 individuals from 5 geographic 34 lowland breeds.Using series population analyses, show...
It is one concern of the researchers how magnesium (Mg) alloys solidify under different conditions and their microstructure evolves during solidification, what are relationship between macroscopic properties various microstructures. Such issues difficult to be revealed through experiments only, especially for newly developed Mg alloys, which there a lack more systematic mature system. However, multi-scale modeling simulation can promote deepen our understanding its deformation mechanism. In...
Interspecific hybrids can exhibit phenotypes that surpass those of their parents, known as heterosis, which is often interest for industrial applications and evolutionary genetics research. However, constructing between distantly related species, such intergeneric yeasts, presents technical challenges. In this study, we established a method to transfer individual chromosomes from Saccharomyces cerevisiae (Sc) into Kluyveromyces marxianus (Km), an emerging model bioproduction. The Sc...
Highlights•The F box protein OsEBF1 negatively regulates rice thermotolerance•OsEBF1 interacts with and degrades the transcription factor OsEIL5•OsEIL5 confers tolerance to heat stress at seedling reproductive stages•As target of OsEIL5, OsPP91 is indispensable for toleranceSummaryUnderstanding regulatory mechanisms underlying plant response important developing climate-resilient crops, including (Oryza sativa). Here, we report that one member ETHYLENE INSENSITIVE3-LIKE family, positively...
Abstract Genome‐wide SNP profiling has yielded insights into the genetic structure of China indigenous pigs, but focused on a limited number populations. Here, we present an analysis population and signals positive selection in 42 Chinese pig populations that represent most extensive phenotypic diversity China, using genotype data 1.1 million SNPs customized Beadchips. This unravels fine‐scale diversity, phylogenic relationships, these populations, which shows remarkably concordance between...
It has been shown that hematological traits are strongly associated with the metabolism and immune system in domestic pig. However, little is known about genetic architecture of traits. To identify quantitative trait loci (QTL) controlling traits, we performed single marker Genome-wide association studies (GWAS) haplotype analysis for 15 495 Chinese Sutai pigs.We identified 161 significant SNPs including 44 genome-wide 11 by GWAS. Most them were located on SSC2. Meanwhile, detected 499...
Phase change materials (PCMs) have the potential to maintain thermal comfort of occupants while reducing energy consumption due their high storage capacity. In this paper, performance active heat conduction–enhanced shape-stabilized phase material (HCE-SSPCM) encapsulated boards, fitted with hot/chilled water pipes were investigated for side-wall cooling and incorporation in an under-floor heating system. Numerical model based on finite difference method was developed study effect HCE-SSPCM...
Abstract Background Pigs were domesticated independently from European and Asian wild boars nearly 10,000 years ago. Chinese indigenous pigs have been historically introduced to improve Europe local pigs. However, the geographic origin biological functions of introgressed genes in modern pig breeds remain largely unknown. Results Here we explored whole-genome sequencing data 266 Eurasian domestic produce a fine-scale map introgression between French Large White (FLW) We show that FLW had...
Chromosomal gains and losses comprise an important type of genetic change in tumors, can now be assayed using microarray hybridization-based experiments. Most current statistical models for DNA copy number estimate total number, which do not distinguish between the underlying quantities two inherited chromosomes. This latter information, sometimes called parent specific is identifying allele-specific amplifications deletions, quantifying normal cell contamination, giving a more complete...
Combining ability is crucial for parent selection in crop hybrid breeding. Many studies have attempted to provide reliable and quick methods identify genome regions parental lines correlating with improved performance. The local haplotype patterns surrounding densely spaced DNA markers include a large amount of genetic information, analysis the relationships between haplotypes performance can insight into underlying which might contribute enhancing combining ability. Here, we generated...
In the 3D free bending forming system, die can be designed either in a sliding type or rolling friction type. Bending die-based is often called normal dies; however, dies-based includes roller and ball structure. current study, impact of three dies on force, bent tube quality was investigated. The obtained results showed that tangential stresses strains tubes formed by were smallest among dies. Besides, spherical bearing force PU reduced drastically after using compared to Moreover,...
The Zhongshan duck (ZSP) is a breed indigenous to China and known for its moderate body size, strong disease resistance, tender meat, little subcutaneous fat. However, the genomic basis of such excellent breeding characteristics remains poorly understood. Therefore, we generated whole-genomes 58 ZSPs 180 other Chinese ducks (60 Jinding ducks, 60 Shan Partridge Liancheng white ducks) identified 10 560 032 single nucleotide polymorphisms 1 334 893 structural variants. Based on genetic...
Summary Heat stress significantly impacts global rice production, highlighting the critical need to understand genetic basis of heat resistance in rice. U2AF ( U2 snRNP a uxiliary f actor) is an essential splicing complex with roles recognizing 3′‐splice site precursor messenger RNAs (pre‐mRNAs). The small subunit (U2AF35) can bind 3′‐AG intron border and promote binding branch‐point sequences introns through interaction large (U2AF65). However, functions U2AF35 plants are poorly understood....
Purpose: To investigate the effect of obesity on alterations in photoreceptor–retinal pigment epithelium (RPE)–choriocapillaris complex. Methods: Two hundred and twenty participants with varying body mass index were enrolled categorized into three groups: normal weight, overweight, obese. Retinal choroidal images obtained using swept-source optical coherence tomography. Automatic segmentation was used for image analysis, evaluating retina thickness parameters such as retinal nerve fiber...
Understanding the mechanism of arsenic (As) accumulation in plants is important reducing As's toxicity to and its potential risks human health. Here, we performed a genome-wide association study dissect genetic basis As contents different maize tissues Xixian, which was irrigated with As-rich surface water, Changge using an population consisting 230 representative inbred lines. Phenotypic data revealed wide normal distribution high repeatability for tissues. The concentrations followed same...
Summary Temperate japonica / geng (GJ) rice yield has significantly improved due to intensive breeding efforts, dramatically enhancing global food security. However, little is known about the underlying genomic structural variations (SVs) responsible for this improvement. We compared 58 long‐read assemblies comprising cultivated and wild species in present study, revealing 156 319 SVs. The phylogenomic analysis based on SV dataset detected putatively selected region of GJ sub‐populations. A...
Abstract Background The dazzling phenotypic characteristics of male Indian peafowl (Pavo cristatus) are attractive both to the female species and humans. However, little is known about evolution phenotype phylogeny these birds at whole-genome level. So far, there no reports regarding genetic mechanism formation leucism plumage in this variant peafowl. Results A draft genome was assembled, with a size 1.05 Gb (the sequencing depth 362×), contig scaffold N50 were up 6.2 11.4 Mb, respectively....
By 2020, the prevalence of Obstructive Sleep Apnea Syndrome (OSAS) in US has reached 26. 6-43.2% men and 8.7-27.8% women. OSAS promotes hypertension, diabetes, tumor growth through unknown means. Chronic intermittent hypoxia (CIH), sleep fragmentation, increased pleural pressure are central mechanisms complications. CIH exacerbates ferroptosis, which is closely related to malignancies. The mechanism ferroptosis disease progression remains unknown.OSAS-related datasets (GSE135917 GSE38792)...
ABSTRACT Objective To evaluate the clinical value of optical genome mapping (OGM) for prenatal diagnosis in fetuses with structural anomalies. Method OGM was performed prospectively 204 cases Detection rates were investigated. Subgroup analysis then conducted. Results Overall, pathogenic or likely (P/LP) chromosome aberrations identified 28 (13.7%) anomalies using OGM, including 12 numerical chromosomal abnormalities, 14 P/LP copy number variations (CNVs) and two balanced rearrangements....
Long non-coding RNAs (lncRNAs) act as universal regulators of various biological processes, but no genome-wide screening lncRNAs involved in the fertility transition photo-thermosensitive genic male sterile (PTGMS) rice line has been reported. Here, we performed strand-specific RNA sequencing at three developmental stages a novel PTGMS Wuxiang S (WXS). A total 3,948 were identified; 622 these detected differentially expressed (DE-lncRNAs) between male-sterile WXS (WXS-S) and male-fertile...