A5059148938- Lymphoma Diagnosis and Treatment
- Histiocytic Disorders and Treatments
- Multiple Myeloma Research and Treatments
- Artificial Intelligence in Healthcare and Education
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Immune Cell Function and Interaction
- Histone Deacetylase Inhibitors Research
- Autoimmune and Inflammatory Disorders Research
- Viral-associated cancers and disorders
- Lung Cancer Treatments and Mutations
- CAR-T cell therapy research
- Peptidase Inhibition and Analysis
- Hematological disorders and diagnostics
- Cancer Immunotherapy and Biomarkers
- COVID-19 diagnosis using AI
- Neutropenia and Cancer Infections
- Acute Myeloid Leukemia Research
- Vascular Malformations and Hemangiomas
- Genital Health and Disease
- Radiomics and Machine Learning in Medical Imaging
- Machine Learning in Healthcare
- Cutaneous lymphoproliferative disorders research
- Eosinophilic Disorders and Syndromes
- Concrete Corrosion and Durability
Sichuan University
2020-2025
West China Hospital of Sichuan University
2020-2025
Fujian Medical University
2025
Xiamen University
2025
Peking Union Medical College Hospital
2018-2024
Southern Medical University
2024
Bridge University
2024
Shandong Provincial Hospital
2024
Shandong First Medical University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2023
ChatGPT (OpenAI), a cutting-edge natural language processing model, holds immense promise for revolutionizing medical education. With its remarkable performance in language-related tasks, offers personalized and efficient learning experiences students doctors. Through training, it enhances clinical reasoning decision-making skills, leading to improved case analysis diagnosis. The model facilitates simulated dialogues, intelligent tutoring, automated question-answering, enabling the practical...
OPINION article Front. Pharmacol., 17 July 2023Sec. Experimental Pharmacology and Drug Discovery Volume 14 - 2023 | https://doi.org/10.3389/fphar.2023.1194216
Rare and complex diseases pose significant challenges to both patients healthcare providers. These conditions often present with atypical symptoms, making diagnosis treatment a formidable task. In recent years, artificial intelligence natural language processing technologies have shown great promise in assisting medical professionals diagnosing managing such conditions. This paper explores the role of ChatGPT, an advanced model, improving rare diseases. By analyzing its potential...
Adult Langerhans cell histiocytosis (LCH) remains poorly defined. We retrospectively studied 266 newly diagnosed LCH patients to understand the clinical presentation, treatment, and prognosis of adult LCH. The median age at diagnosis was 32 years (range, 18-79 years). At time diagnosis, 40 had single lesions within a system, 18 pulmonary LCH, 26 multiple system (SS-m), 182 multisystem disease (MS). most common organ involved in MS bone (69.8%), followed by pituitary (61.5%) lung (61.0%)....
Background In recent years, with the continuous development of treatments for hematological malignancies (HMs), remission and survival rates patients HMs have been significantly improved. However, because severe immunosuppression long-term recurrent neutropenia during treatment, incidence mortality bloodstream infection (BSI) were all high in HMs. Therefore, we analyzed pathogens’ distribution drug-resistance patterns developed a nomogram predicting 30-day BSIs among Methods this...
Abstract Objectives Survivors after pediatric Hodgkin lymphoma (HL) and non-Hodgkin (NHL) are with lifetime risk for second primary malignancy (SPM). This necessitates a thorough analysis to better understand the potential long-term health implications these individuals. Methods We used US-wide population-based cancer registry data quantify SPM identify its incidence patterns among patients. Results observed 4.74-fold (95% CI 4.27–5.25) 3.40-fold 2.78–4.10) increased risks of in survivors HL...
Composite lymphoma (CL) is rare. We conducted an analysis of 53 329 cases diffuse large B-cell (DLBCL), 17,916 Hodgkin (HL), and 869 composite HL DLBCL from the SEER database diagnosed between 2000 2019. Incidence rates showed increasing trends with age for CL DLBCL, while exhibited 2 peak incidence rates: 42.05 (95% CI: 40.88-43.25) per million group 20-24 43.20 41.13-45.35) 75-79. Higher were observed in males (CL, 0.68, 95% 0.62-0.74; HL, 29.65, 29.27-30.03; 86.18, 85.51-86.86) compared...
Background: Small cell lung cancer (SCLC) is characterized by extreme invasiveness and lethality. There have been very few developments in its diagnosis treatment over the past decades. It urgently needed to explore potential novel biomarkers drug targets for SCLC. Methods: Two-sample Mendelian Randomization (MR) was performed investigate causal associations between SCLC plasma proteins using genome-wide association studies (GWAS) summary statistics of from Transdisciplinary Research Into...
Abstract N6-methyladenosine (m 6 A) is the most prevalent modification of eukaryotic RNA, which recognized by m A-binding proteins (“readers”) and thereby mediates multiple biological processes. Dysregulation A readers has been linked to various pathologies, but therapeutic potential small molecule inhibitors targeting m6A unknown. Here we report identification characterization a highly potent selective first-in-class inhibitor (YL-5092) YT521-B homology (YTH) domain-containing protein 1...
Accumulating evidence have indicated that regulatory T cells (Tregs) play an essential role in cell-mediated immune response and development of multiple myeloma (MM). CD4+FoxP3+ are composed three phenotypically functionally distinct subpopulations: CD45RA+FoxP3lo resting Tregs (rTregs), CD45RA-FoxP3hi activated (aTregs) CD45RA-FoxP3lo non-suppressive (non-Tregs). We aimed to clarify the frequency function these subpopulations newly diagnosed monoclonal gammopathy undetermined significance...