A5100329045- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Neuroendocrine Tumor Research Advances
- Caveolin-1 and cellular processes
- Immune Cell Function and Interaction
- MRI in cancer diagnosis
- Insect symbiosis and bacterial influences
- Antimicrobial Peptides and Activities
- Vector-borne infectious diseases
- Neuroblastoma Research and Treatments
- Nanoplatforms for cancer theranostics
- Sphingolipid Metabolism and Signaling
- Aortic aneurysm repair treatments
- Cancer, Hypoxia, and Metabolism
- Rabbits: Nutrition, Reproduction, Health
- Rabies epidemiology and control
- Cardiac and Coronary Surgery Techniques
- Hematopoietic Stem Cell Transplantation
- Renal cell carcinoma treatment
- Nuclear Receptors and Signaling
- Sodium Intake and Health
- Immune cells in cancer
- Antimicrobial agents and applications
- Telomeres, Telomerase, and Senescence
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2025
Qingdao University of Science and Technology
2025
Guizhou Academy of Agricultural Sciences
2025
Fu Wai Hospital
2025
Beijing HuiLongGuan Hospital
2012-2025
Peking University
2025
Peking Union Medical College Hospital
2008-2024
Yuhuangding Hospital
2024
Qingdao University
2024
Bridge University
2023
Abstract Organic photoelectrochemical transistor (OPECT) as a photo‐electric‐biological technology, is shown considerable potential for high‐performance detection in biological sensing. High gating effect and current always pursuit to improve the performances of OPECT, but date, their inherent channel materials invariant structure limit further development. The challenge addressed through new bipolar‐driven OPECT signal amplification efficient modulation. Herein, inspired by self‐powered...
Bacterial infection of wounds delays the healing process, increases risk chronic trauma associated with pain and complications, offers a breeding ground for drug-resistant bacteria. A rapid effective eradication bacterial species in wound area is thus important. Herein, we designed phototherapeutic antibacterial platform based on peptides copper sulfide nanodots (CuS NDs) multi-mechanistic bacteria colonized surface. The antimicrobial peptide weaves into network form hydrogel, which supports...
We aim to compare the safety and effectiveness of KangDuo (KD)-Surgical Robot-01 (KD-SR-01) system da Vinci (DV) for robot-assisted radical nephroureterectomy (RARNU).
The optimal glycemic control level in diabetic patients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary (On-Pump) remains unclear. Therefore, this study aimed to investigate the effect of different blood glucose levels and fluctuations on in-hospital adverse outcomes on-pump CABG.A total 3918 diabetes CABG were reviewed study. A 1638 eligible for inclusion categorized into strict, moderate liberal groups based post-operative mean < 7.8 mmol/L, from 9.9 mmol/L ≥ 10.0...
OBJECTIVE To examine the incidence of stroke in Chinese adults with newly diagnosed type 2 diabetes (NDD), impaired glucose tolerance (IGT), and normal (NGT) over a 34-year follow-up period. RESEARCH DESIGN AND METHODS This cohort study included participants NDD, IGT, NGT initially identified 1986 Da Qing Diabetes Prevention Study who were followed up for 34 years. Patients IGT randomized into 6-year lifestyle intervention or control group. The hazard ratios (HRs) determined across three...
Accumulating evidence have indicated that regulatory T cells (Tregs) play an essential role in cell-mediated immune response and development of multiple myeloma (MM). CD4+FoxP3+ are composed three phenotypically functionally distinct subpopulations: CD45RA+FoxP3lo resting Tregs (rTregs), CD45RA-FoxP3hi activated (aTregs) CD45RA-FoxP3lo non-suppressive (non-Tregs). We aimed to clarify the frequency function these subpopulations newly diagnosed monoclonal gammopathy undetermined significance...
As the most common pathogen of community and nosocomial infection, resistance Staphylococcus aureus (S. aureus) to traditional antibiotics is still increasing with years. Although potent antibacterial activity antimicrobial peptides (AMPs) has been widely confirmed, unpredictable cytotoxicity remains biggest obstacle their clinical application. The development a targeted drug delivery system for S. practical strategy ameliorate inherent limitations AMPs. In this work, we constructed an AMP...
Abstract Major depressive disorder (MDD) is a common chronic mental disease with diverse clinical presentation. Although the genome‐wide association study (GWAS) has remarkably facilitated understanding of genetic mechanisms MDD at deep molecular level, combined effect these disease‐underlying genes still needs further investigation. A total 1,062 unrelated patients and 992 healthy subjects were recruited from Chinese Han population to test 16 MDD‐associated identified by GWAS. tag SNP‐based...
Schistosoma sinensium belongs to the Asian and is transmitted by freshwater snails of genus Tricula. Rodents are known definitive hosts S. sinensium. In 2016, suspected schistosome eggs were found in feces northern tree shrew (Tupaia belangeri) a field Lufeng County (latitude, 25°04′50″ N; longitude, 102°19′30″ E; altitude 1820 m), Yunnan Province, China. Morphological analysis suggested that was 18S, 12S CO1 genes sequencing phylogenetic showed this species had highest similarity occupied...
Primary vitreoretinal lymphoma (PVRL) is a rare variant of primary central nervous system (CNS) lymphoma, for which currently there are no optimal treatment options. This prospective single-center study enrolled immunocompetent patients with newly diagnosed PVRL between August 2018 and January 2020. Patients received local systemic therapies: intravitreal methotrexate (MTX, 400 μg, 0.1 mL) injections 1 year (total 16 injections) six cycles the rituximab (375 mg/m 2 on day 1) lenalidomide (25...
The patient, a 43-year-old male, was admitted to the hospital with gradually aggravated exertional palpitations and chest tightness over 2-day period. Upon admission, cardiac ultrasound revealed aortic valve redundancy, however multiple blood culture investigations came back negative. Blood mNGS perfected, revealing Coxiella burnetii , diagnosis of Q fever (query fever) established. temperature inflammatory indices patient were all normal treatment vancomycin before surgery. But for...
The intestinal epithelium has an average lifespan of 4-5 days. Normally, primary epithelial cells can be cultured for about 15 days in vitro. aim this study was to explore methods isolate and immortalize (IECs) tree shrews order establish a new resource experimental material provide cell model drug development infection mechanism research. Tissue from the small intestine digested with collagenase XI, neutral protease I, dithiothreitol. human telomerase reverse transcriptase gene (hTERT)...
Abstract Background Ixodes granulatus is of significant research value as the primary vector Lyme disease in Asia, yet bacterial community structure and diversity carried by these ticks have not been reported so far. Part bacteria can affect tick development transmission tick-borne pathogens. With emergence new pathogens, it necessary to identify microbiome I. . Methods were collected from rodent animals Binchuan, China. The DNA was extracted non-engorged adult female Sequencing V3-V4...
Abstract Aim Whether systolic/diastolic blood pressure (SBP/DBP) values of 130‐139/80‐89 mmHg should be defined as hypertension has been debated for decades. We aimed to characterize the effect high‐normal BP on cardiovascular disease (CVD) events and deaths. Methods In total, 1726 individuals from original Da Qing IGT Diabetes Study were enrolled, divided into normal group (SBP <130 DBP <80 mmHg), 130‐139 and/or 80‐89 mmHg) ≥140 ≥90 mmHg). CVD their components assessed 1986 2016....
Background: This study aimed to evaluate the feasibility and effectiveness of Gore Excluder aortic stent graft (WL & Associates, Inc., Flagstaff, AZ) using C3 Delivery System after physician modification fenestration for urgent treatment patients with abdominal aneurysm showing hostile neck anatomy. Case summary: Three cases anatomy symptom pain were reported. The same method was applied align target superior mesenteric artery bilateral renal arteries 1 scallop 2 fenestrations, followed by...
This study was aimed to explore the effects of lymphoma cells on differentiation monocytes from peripheral blood tumor-associated macrophages (TAM) and effect TAM proliferation in vitro, investigate difference between newly diagnosed patients healthy volunteers. Blood samples were obtained 15 8 Monocytes isolated by Ficoll- Hypaque density gradient centrifugation CD14 immuno-magnetic beads. Then directly co-cultured with HUT-78 using Transwell apparatus vitro. Expression markers (CD68 CD163)...