A5087235659- Metabolism, Diabetes, and Cancer
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Diabetes Management and Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pancreatic function and diabetes
- Cardiovascular Health and Risk Factors
- Diet and metabolism studies
- Diabetes Management and Education
- Lipid metabolism and disorders
- Nutrition, Genetics, and Disease
- Diet, Metabolism, and Disease
- Diabetes and associated disorders
- Liver Disease Diagnosis and Treatment
- Traditional Chinese Medicine Studies
- Geological and Geochemical Analysis
- Nitric Oxide and Endothelin Effects
- Thyroid Cancer Diagnosis and Treatment
- Sphingolipid Metabolism and Signaling
- Cardiovascular Function and Risk Factors
- Metabolomics and Mass Spectrometry Studies
- Blood Pressure and Hypertension Studies
- Regulation of Appetite and Obesity
- Corneal Surgery and Treatments
- Ion channel regulation and function
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
Fu Wai Hospital
2012-2025
China-Japan Friendship Hospital
2016-2025
Peking Union Medical College Hospital
2020-2025
Shandong Eye Hospital
2022-2025
Shandong First Medical University
2022-2025
Nanjing University
2021-2024
Chinese Academy of Sciences
2018-2023
Fujian Institute of Research on the Structure of Matter
2023
Yan'an University
2023
IMPORTANCE Noncommunicable chronic diseases have become the leading causes of mortality and disease burden worldwide.OBJECTIVE To investigate prevalence diabetes glycemic control in Chinese adult population.DESIGN, SETTING, AND PARTICIPANTS Using a complex, multistage, probability sampling design, we conducted cross-sectional survey nationally representative sample 98 658 adults 2010.MAIN OUTCOMES MEASURES Plasma glucose hemoglobin A 1c levels were measured after at least 10-hour overnight...
Abstract Background Myocardial ischemia/reperfusion injury is the major cause of morbidity and mortality for cardiovascular diseases. Dopamine D 2 receptors are expressed in cardiac tissues. However, roles dopamine myocardial cardiomyocyte apoptosis unclear. Here we investigated effects both agonist (bromocriptine) antagonist (haloperidol) on cultured neonatal rat ventricular myocytes induced by injury. Methods was simulated incubating primarily cardiomyocytes ischemic (hypoxic) buffer...
OBJECTIVE Despite its growing prevalence in China, the extent to which diabetes leads excess cardiovascular disease (CVD) mortality and all-cause is unclear. RESEARCH DESIGN AND METHODS We compared death rates causes of among 630 people with newly diagnosed (NDD) 519 normal glucose tolerance (NGT) who, 1986, were identified as a result screening 110,660 adults aged 25–74 years for Da Qing, China. RESULTS During 23 follow-up, 338 (56.5%) participants NDD 100 (20.3%) NGT died. CVD was...
Abstract Aim To evaluate whether 1‐hour plasma glucose (1hPG) can be a comparable measurement to 2‐hour (2hPG) in identifying individuals at high risk of developing diabetes. Methods A total 1026 non‐diabetic subjects the Da Qing IGT and Diabetes Study were included classified according baseline postload 1hPG. The participants followed up assessed 6‐, 20‐ 30year follow‐up for outcomes including diabetes, all‐cause cardiovascular mortality, disease (CVD) events, microvascular disease. We then...
Background The association between years of non-diabetes status after diagnosis impaired glucose tolerance (IGT) and the risk long-term death cardiovascular outcomes needed to be clarified. Methods findings In this post hoc analysis, we included 540 individuals with IGT who participated in original Da Qing Diabetes Prevention Study (DQDPS). DQDPS, all participants were diagnosed by a 75 g oral test randomized intervention or control groups 6-year lifestyle trial. After completion trial,...
OBJECTIVE People with impaired glucose tolerance (IGT) have increased risk of mortality and a high progression to diabetes, but the extent that excess is associated IGT per se or result subsequent diabetes unclear. RESEARCH DESIGN AND METHODS We compared before after development among 542 persons initially who participated in 6-year lifestyle prevention trial were followed-up from 1986 2009. RESULTS During 23-year follow-up, 174 (32.1%) died, an overall death rate 15.9/1,000 person-years....
Type 2 diabetes [T2D] and thyroid dysfunction [TD] often co-occur, have overlapping pathologies, their risk increases with age. Since 1995, universal salt iodization has been implemented in China to prevent disorders caused by iodine deficiency. However, after two decades of implementation iodization, the prevalence TD elderly Chinese patients T2D is not well described may underestimated. We conducted a questionnaire-based survey across 24 endocrinology centers between December 2015 July...
To investigate the association of potential cardiovascular disease (CVD) biomarkers in patients with type 2 diabetes.We enrolled 120 participants (aged 61.5-69.5 years) diabetes and 60 62.5-73.5 normal glucose tolerance discovery group from original Da Qing Diabetes Study. Their status was confirmed 1986; then, were followed over 23 years to collect CVD outcome data. Untargeted targeted metabolomics analyses based on ultra-high-performance liquid chromatography-tandem mass spectrometry used...