A5003289715- Acute Myeloid Leukemia Research
- Chronic Lymphocytic Leukemia Research
- Lymphoma Diagnosis and Treatment
- RNA modifications and cancer
- CNS Lymphoma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- RNA Research and Splicing
- Retinoids in leukemia and cellular processes
- Epigenetics and DNA Methylation
- Immune Cell Function and Interaction
- Pleural and Pulmonary Diseases
- Autoimmune and Inflammatory Disorders Research
- Cancer-related gene regulation
- Alcohol Consumption and Health Effects
- Tracheal and airway disorders
- Phytochemical and Pharmacological Studies
- Tea Polyphenols and Effects
- Smart Cities and Technologies
- Ferroptosis and cancer prognosis
- Vasculitis and related conditions
- Sirtuins and Resveratrol in Medicine
- Neutropenia and Cancer Infections
- Salivary Gland Tumors Diagnosis and Treatment
- Botanical Studies and Applications
Sichuan University
2011-2025
West China Hospital of Sichuan University
2016-2025
Institute of Vegetables and Flowers
2025
Chinese Academy of Agricultural Sciences
2025
Ministry of Agriculture and Rural Affairs
2025
Beijing Normal University
2025
Tongji University
2018-2024
Shanghai Pulmonary Hospital
2018-2024
Qilu Hospital of Shandong University
2024
Xi'an University of Science and Technology
2024
Src family tyrosine kinase (SFK) activation is associated with ovarian cancer progression. Therefore, SFKs are targets for the development of potential treatments cancer. Dasatinib a inhibitor that SFK activity, and used treatment B cell Abelson lymphomas. At present time, effect dasatinib on not clear. The aim study was to investigate antitumor activity dasatinib, alone in combination paclitaxel, vitro vivo. In study, expression phospho‑Src-Y416 (p‑Src) measured six lines using western...
Urban–rural fragmentation represents a significant challenge encountered by nations globally, particularly in both developing and developed contexts, during the modernisation process. This study examines effects of rural land system reform on facilitating integrated development between urban areas. The analysis impact 2010 liberalisation transfer policy employs dual machine learning model, utilising provincial-level data from China spanning 2005 to 2022, address limitations traditional...
Background Dual induction with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has made acute promyelocytic leukemia (APL) a curable disease. However, differentiation syndrome (DS) can be life-threatening complication of therapy. It is considered to result from severe systemic inflammatory response mediated by increased expression cytokines, chemokines, adhesion molecules on differentiating blast cells. The kidney, as vital organ rich in the capillary endothelium, could targeted...
The digital economy plays an increasingly crucial role in bridging the gap between urban and rural areas. This study investigates how development of can foster integrated areas by optimizing factor allocation, with emphasis on its potential to narrow urban-rural divide. aims examine impact integration, focusing particularly mediating optimized allocation. Using panel data from 30 Chinese provinces 2011 2022, we construct indicators for integration. analysis employs a two-way fixed-effects...
Abstract Asiatic hybrid lilies (Lilium spp.) are favored by consumers for their vibrant colors and diverse anthocyanin pigmentations. Although the regulation of accumulation transcription factors has been explored, role HD-Zip proteins with ethylene-responsive element binding factor associated amphiphilic repression (EAR) motifs in modulating levels through histone acetylation remains unclear. In this study, we identified Lhhomeobox-leucine zipper protein 4 (LhHB4) as a δ group member II...
Abstract N6-methyladenosine (m 6 A) is the most prevalent modification of eukaryotic RNA, which recognized by m A-binding proteins (“readers”) and thereby mediates multiple biological processes. Dysregulation A readers has been linked to various pathologies, but therapeutic potential small molecule inhibitors targeting m6A unknown. Here we report identification characterization a highly potent selective first-in-class inhibitor (YL-5092) YT521-B homology (YTH) domain-containing protein 1...
Sea buckthorn (SB) has been indicated to have hypoglycemic potential, but its effects on glucose in people with impaired regulation (IGR) are still unclear. This work presents a randomized, double-blinded, two-way crossover study. A total of 38 subjects IGR completed the intervention consuming sea fruit puree (SBFP, 90 mL/day, five weeks), washing out (four and then placebo (90 weeks) or reverse order. In our methodology, unified questionnaire was used gather information physical activity...
The clinical efficacy of robot-assisted thoracic surgeries has been explored by numerous recent studies. Nonetheless, since current standard robotic systems (da Vinci Xi system) were intended for multiportal surgical processes and staplers still unavailable in the developing world, obstacles remain concerning feasibility uniportal surgeries.A hybrid robotic-assisted thoracoscopic surgery (RATS) modality utilizing video-assisted (VATS) was investigated Shanghai Pulmonary Hospital....
Abstract Introduction Immune factors contribute to the onset of myelodysplastic syndrome (MDS). Arginine metabolism affects tumor‐associated macrophage (TAM) polarization. This study investigated infiltration TAMs and effect arginine key enzymes on MDS prognosis. Methods We used GEO (Gene Express Omnibus database) dataset “GSE19429” analyze compare metabolism‐associated pathways between patients with excess blasts those without. The markers enzymes, including CD68, iNOS, ARG1 ASS1 were...
Background: Subxiphoid uniportal video-assisted thoracoscopic surgery (SVATS) has been known as feasible and safe approach for lobectomy with acceptable results. Its learning curve is slightly harder than the intercostal approach. The aim of this article to view evolution surgical technique change in results progress a trial guide surgeons aiming apply technique. Methods: Four hundred thirty-eight patients underwent SVATS from September 2014 November 2017. were divided into four groups...
Daratumumab is a humanized anti-CD38 IgG1 monoclonal antibody which could be used for multiple myeloma (MM). MM with plasma-cell leukemia (PCL) transformation highly aggressive and resistant to conventional therapy. Novel therapeutics are needed PCL, daratumumab may play role. We report case of relapsed/refractory (RRMM)-transformed PCL successfully treated daratumumab. The was 42-year-old man who diagnosed 2 years ago relapsed after six cycles bortezomib-based chemotherapy. patient rapidly...
Zanubrutinib is a Bruton tyrosine kinase (BTK) inhibitor used in B cell malignancy treatment and generally well tolerated most patients. Zanubrutinib-induced aseptic meningitis currently not reported. Herein, we present the first case of zanubrutinib-induced meningitis. A 33-year-old woman was diagnosed with relapsed/refractory follicular lymphoma subsequently developed after receiving zanubrutinib treatment. We reviewed literature uncovered lack current reports on or other BTK...
Objective: To evaluate the clinical characteristics, MYD88(L265P) mutation, CXCR4(W)HIM mutation and prognosis in patients with Waldenström macroglobulinemia (WM). Methods: The International Prognostic Scoring System for symptomatic WM (WPSS) , overall survival (OS) were retrospectively assayed 93 newly diagnosed at Peking Union Medical College Hospital during January 2000 to August 2016. tested among 34 patients. Results: median age of was 64 years (range, 33-85 years) a male-to-female...