A5102014142- Aquaculture disease management and microbiota
- Immune cells in cancer
- Metabolomics and Mass Spectrometry Studies
- Tryptophan and brain disorders
- Endometrial and Cervical Cancer Treatments
- Invertebrate Immune Response Mechanisms
- Estrogen and related hormone effects
- Lipid metabolism and disorders
- Plant Gene Expression Analysis
- Retinoids in leukemia and cellular processes
- S100 Proteins and Annexins
- Cancer-related gene regulation
- Cancer, Lipids, and Metabolism
- Gut microbiota and health
- Heavy Metals in Plants
- Nerve injury and regeneration
- Photosynthetic Processes and Mechanisms
- Wnt/β-catenin signaling in development and cancer
- Cytokine Signaling Pathways and Interactions
- RNA modifications and cancer
- Angiogenesis and VEGF in Cancer
- Sphingolipid Metabolism and Signaling
- Calcium Carbonate Crystallization and Inhibition
- Caveolin-1 and cellular processes
- Curcumin's Biomedical Applications
Guangzhou Medical University
2014-2024
Ollscoil na Gaillimhe – University of Galway
2024
Nantong University
2024
Ludong University
2021-2023
Kunming Medical University
2022
Henan University of Urban Construction
2021
China National GeneBank
2016-2021
Guangzhou Women and Children Medical Center
2014-2020
Peking University
2018-2020
Central South University
2016
A new gene, SG1, was identified in a slow-greening mutant (sg1) isolated from an ethylmethanesulphonate-mutagenized population of Arabidopsis thaliana. The newly formed leaves sg1 were initially albino, but gradually became pale green. After 3 weeks, the as green those wild-type plants. Transmission electron microscopic observations revealed that displayed delayed proplastid to chloroplast transition. results map-based cloning showed SG1 encodes chloroplast-localized tetratricopeptide...
Abstract Tissue regeneration is a hot topic in the field of biomedical research this century. Material composition, surface topology, light, ultrasonic, electric and magnetic fields (MFs) all have important effects on process. Among them, MFs can provide nearly non-invasive signal transmission within biological tissues, materials convert into series signals related to processes, such as mechanical force, heat, drug release, etc. By adjusting materials, desired cellular or molecular-level...
Peripheral nerve injury (PNI) seriously affects the health and life of patients, is an urgent clinical problem that needs to be resolved. Nerve implants prepared from various biomaterials have played a positive role in PNI, but effect should further improved thus new urgently needed. Ovalbumin (OVA) contains variety bioactive components, low immunogenicity, tolerance, antimicrobial activity, non-toxicity biodegradability, has ability promote wound healing, cell growth properties. However,...
Diagnosis of endometrial cancer is primarily based on symptoms and imaging, with early‐stage disease being difficult to diagnose. Therefore, development potential diagnostic biomarkers required. Metabolomics, a quantitative measurement the dynamic metabolism in living systems, can be applied determine metabolite profiles different states. Here, serum metabolomics was performed 46 early stage patients healthy volunteers. In addition, effect identified metabolites tumor cell behavior...
Questions remain about the effects of rare earth elements (REEs) on reproductive health, and no study has explored in utero exposure to REEs risk orofacial clefts (OFCs). We recruited subjects from a case-control conducted Shanxi Province, China. Concentrations fifteen were quantified umbilical cord samples by means Inductively Coupled Plasma Mass Spectrometry measurements. employed logistic regression weighted quantile sum (WQS) models estimate association between exposures OFCs. Of 226...
Microbial dysbiosis has an increasingly appreciated impact on carcinogenesis, and the cervicovaginal microbiome plays a critical role in microenvironmental inflammation. Here, we investigated involvement of female genital tract Peptostreptococcus species gynecological cancer via indoleacrylic acid (IAA). IAA production from effect bacterial culture tumor growth vivo were examined. The cytokine indoleamine-2,3-dioxygenase 1 (IDO1) expression endometrial (EC) cell line, as well their Treg Teff...
The Pacific oyster, Crassostrea gigas , is widely distributed and substantially important to shellfish cultivation. Oysters with melanin-colored shells soft parts are increasingly popular of high economic value. However, the distribution synthesis melanin in C. remains unclear there have been only few relevant studies on it. In this study, transmission electron microscopy (TEM) was used observe epidermis dark mantle tissue. Melanocytes containing melanosomes were observed below epidermis,...
Elucidating the mechanism for high metastasis capacity of Endometrial cancer (EC) is crucial to improve treatment outcomes EC. We have recently reported that nicotinamide N-methyltransferase (NNMT) overexpressed in EC, especially and predicts poor survival chemotherapy patients. Here, we aimed determine function NNMT on Additionally, analysis public datasets indicated involved cholesterol metabolism. In vitro, overexpression promoted migration invasion EC by reducing levels cytoplasm cell...
Aims: To explore the diagnostic biomarkers for diagnosing endometriosis. Background: Endometriosis is a benign, progressive, estrogen-dependent gynecological disorder that has highly variant prevalence. Therefore, it essential to develop reliable endometriosis diagnosis. Objective: Methods: Based on transcriptome data from GSE145701, we identified potential therapeutic targets through intersection of endometriosis-related genes weighted gene correlation network analysis (WGCNA) and...
Abstract Background In our previous study, we found that formyl peptide receptor 2 (FPR2) promoted the invasion and metastasis of epithelial ovarian cancer (EOC) could be a prognostic marker for EOC. this aimed to study possible mechanism FPR2 in promoting EOC progression. Methods cell lines with ectopic expression knockdown as well their control were established, change RhoA each line was evaluated by real time quantitative polymerase chain reaction (RT-qPCR) Western blot. Wound healing...
The Fujian oyster ( Crassostrea angulate ) is an important marine bivalve mollusk with high economic value. Gene function research and gene editing techniques have broad application prospects in oyster. clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system has been widely used for genome engineering many species. CRISPR-mediated also successfully the Pacific through direct delivery of CRISPR/Cas9 components into embryos by microinjection....
The aim of the study was to investigate therapeutic potential Berbamine-loaded lipid nanoparticles (BBM-NPs) in pancreatic cancer. Dopamine polymerization-polylactide-TPGS were synthesized prepare BBM-NPs, and change particle size BBM-NPs measured. Cell Counting Kit-8 (CCK8) assay, plate cloning experiment, apoptosis analysis performed evaluate cytotoxicity against cancer cells (PANC-1 AsPC-1). Migration invasion abilities tumor determined by Transwell wound healing assays. intracellular...