A5052322444- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Histiocytic Disorders and Treatments
- Hemoglobinopathies and Related Disorders
- Viral-associated cancers and disorders
- Meningioma and schwannoma management
- Blood transfusion and management
- Vascular Malformations Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Blood groups and transfusion
- Multiple Myeloma Research and Treatments
- IgG4-Related and Inflammatory Diseases
- Sarcoma Diagnosis and Treatment
- Teratomas and Epidermoid Cysts
- Spinal Hematomas and Complications
- Bone Tumor Diagnosis and Treatments
- Adipose Tissue and Metabolism
- Brain Metastases and Treatment
- Congenital heart defects research
- Fungal Infections and Studies
- Vascular Procedures and Complications
- Cancer Immunotherapy and Biomarkers
- Caveolin-1 and cellular processes
- Autoimmune and Inflammatory Disorders
- Medical Imaging and Pathology Studies
Drexel University
2022
Neurological Surgery
2022
Allegheny Health Network
2022
Allegheny General Hospital
2022
Duke University Hospital
2021
Duke Medical Center
2021
West Virginia University
2015-2020
Duke University
2018-2020
Memorial Hospital
2016
Brown University
2016
Aims To determine the utility of clinical, morphological and phenotypical features in differential diagnosis plasmablastic lymphoma myeloma with features. Methods All neoplasms identified from a 15-year retrospective search were reviewed classified into ‘lymphoma’, ‘myeloma’ or ‘indeterminate’. The classification was then compared previously established clinical diagnosis. Lessons learned this review used to design diagnostic algorithm for pathologists use absence known history. Results...
Although hemoglobin thresholds for red blood cell (RBC) transfusion have decreased, double-unit RBC practices persist. We studied the effects switching from predominantly to single-unit transfusions had on utilization and clinical outcomes malignant hematology patients.Retrospective chart review compared patients before after implementing policy. Hemoglobin threshold was 8.0 g/dL both groups. metrics included number of units transfused, transfused per admission, episodes. Clinical length...
Lipomatous meningiomas are a very rare form of brain consisting fat accumulation within the tumor. Magnetic resonance imaging (MRI) or computerized tomographic (CT) can be utilized to visualize accumulations, but histopathologic staining is necessary in order make definitive diagnosis. The key feature identification adipocyte-like cells tumor, other markers have also been identified. In this case report and review literature, we discuss how recognize symptoms associated with lipomatous...
Rare pilocytic astrocytomas (PA) have been described to arise in the ventricles of children. They are even less common this location for adult population. We present case a 44-year old man presenting with vision and mental status changes. Brain imaging revealed an intraventricular mass within right ventricular atrium, most consistent meningioma. Microscopic examination neoplasm composed elongated plump bipolar astrocytes arranged fascicular architecture, accompanied by foci containing...
Background: Teratomas are a unique family of tumors derived from two or more the three embryonic layers: endoderm, mesoderm, and ectoderm. Mature teratomas comprised most well-differentiated tissue types may contain skin, hair, teeth, smooth muscle, respiratory tissues, etc. Infrequently, mature be found within central nervous system and, in exceedingly rare cases, occur spinal cord itself (i.e., intramedullary/intradural). Case Description: A 78-year-old female presented with subacute...
Constitutional mismatch repair deficiency syndrome is a cancer predisposition caused by autosomal recessive biallelic (homozygous) germline mutations in the genes (MLH1, MSH2, MSH6, and PMS2). The clinical spectrum includes neoplastic non-neoplastic manifestations. We present case of 7-year-old boy who presented with T-lymphoblastic lymphoma glioblastoma, together manifestations including corpus callosum agenesis, arachnoid cyst, developmental venous anomaly, hydrocephalus. Gene mutation...
Malignant pleural mesothelioma represents a rare etiology of lung cancer metastasis to the brain. Neurologically symptomatic presentations are extremely as these metastatic lesions detected in late stages disease. Despite many highly heterogenous treatment techniques reported literature, overall survival is poor. A 72-year-old male with history presented recurrent episodes altered mental status, confusion and expressive aphasia. Imaging indicated large hemorrhagic, enhancing lesion anterior...
Plasmablastic lymphoma (PBL) is an aggressive B-cell that shows a plasma cell phenotype while lacking expression of antigens. Multiple myeloma (MM) indolent disorder cells may similarly show plasmablastic morphology, thus posing diagnostic challenge. We present the clinical and pathologic findings series neoplasms. A 10-year retrospective search our files …
Alveolar rhabdomyosarcoma (RMS) is an aggressive soft tissue mass demonstrating rapid growth, dissemination, and leptomeningeal spread. Primary diagnosis usually established by core biopsy. In rare cases, cytopathologic evaluation indicated to identify recurrent or metastatic disease. We present a case of 24‐year‐old man with previously diagnosed alveolar RMS the foot who presented our institution back pain. A lumbar puncture was performed cerebrospinal fluid (CSF) showed atypical cells...
Immunocompromised patients, especially organ transplant recipients, are at risk for opportunistic infections. Cryptococcus, a ubiquitous environmental fungus, can cause potentially fatal infection in such hosts. While it involve any the human body, respiratory and central nervous systems commonly affected. We present case of disseminated cryptococcal liver recipient whom initial presentation was bilateral axillary lymphadenopathy, relatively rare clinical manifestation. Rapid diagnosis...
Endogenous pulmonary thromboemboli are a common cause of noncardiac sudden natural death. Embolism exogenous material is rare but potential finding in autopsies following surgeries, medical procedures, penetrating trauma, and nonparenteral drug abuse. This report describes the first case suture embolism left superior lobar artery complicated abdominal surgery.
A number of neoplasms the central nervous system can demonstrate diffuse eosinophilic globules, known to be secretory products corresponding cell type, but they have not been a salient feature in descriptions classic ependymoma. Here, we present case posterior fossa ependymoma demonstrating glassy PAS-positive, diastase-resistant, globules with light microscopic and ultrastructural features resembling Reissner fiber, product subcommissural organ. While there has single published description...