A5033678424- Advanced Fluorescence Microscopy Techniques
- Digital Holography and Microscopy
- Optical Coherence Tomography Applications
- Photoacoustic and Ultrasonic Imaging
- Metamaterials and Metasurfaces Applications
- Cell Image Analysis Techniques
- Digital Imaging for Blood Diseases
- Machine Learning and ELM
- Spectroscopy and Laser Applications
- Antenna Design and Analysis
- Machine Learning and Algorithms
- Image Processing Techniques and Applications
- Advanced Antenna and Metasurface Technologies
- Flow Measurement and Analysis
- Laser Design and Applications
- Advanced Image Processing Techniques
- Cellular Mechanics and Interactions
- Microfluidic and Bio-sensing Technologies
- Biomedical Ethics and Regulation
- Image Enhancement Techniques
- Phagocytosis and Immune Regulation
- SARS-CoV-2 and COVID-19 Research
- Agricultural Engineering and Mechanization
- Orbital Angular Momentum in Optics
- Water Quality Monitoring Technologies
Shanghai Jiao Tong University
2024-2025
Shanghai First People's Hospital
2024-2025
Harbin Institute of Technology
2019-2024
Ministry of Industry and Information Technology
2022-2024
Imaging Center
2024
Nanjing Institute of Agricultural Mechanization
2023
Ministry of Agriculture and Rural Affairs
2023
ORCID
2021
X-Fab (Germany)
2018
Shandong Academy of Sciences
2013-2016
Differential interference contrast (DIC) microscopy allows high-contrast, low-phototoxicity, and label-free imaging of transparent biological objects, has been applied in the field cellular morphology, cell segmentation, particle tracking, optical measurement others. Commercial DIC based on Nomarski or Wollaston prism resorts to two polarized waves with a lateral differential offset (shear) axial phase shift (bias). However, shear generated by these prisms is limited rectilinear direction,...
In fluorescence microscopy, computational algorithms have been developed to suppress noise, enhance contrast, and even enable super-resolution (SR). However, the local quality of images may vary on multiple scales, these differences can lead misconceptions. Current mapping methods fail finely estimate quality, challenging associate SR scale content. Here, we develop a rolling Fourier ring correlation (rFRC) method evaluate reconstruction uncertainties down scale. To visually pinpoint regions...
Benefiting from prominent performance in various scientific fields, metasurface research has been flourishing over the past decade. Huygens' metasurface, as an emerging subcategory of can theoretically achieve full control electric field distribution within subwavelength scale. Driven by its outstanding manipulation capacity, three-dimensional holography utilizing broadband is demonstrated microwave regime this paper. For working properties, two types equivalent circuit are integrated into...
The diverse design freedom and exotic electromagnetic properties of metasurfaces enable them to achieve unprecedented capability superiority with regard conventional optical elements. Herein, a bifunctional microwave metasurface an asymmetric bidirection transmission phase that can be controlled is reported. proposed composed bilayered double‐arrow‐shaped structures sandwiching subwavelength metal grating. Such not only linear polarization (LP) conversion for two oppositely directed wave...
Abstract The demand for achromatic ultrathin flat lenses has become increasingly stringent, particularly high‐performance imaging and display applications. Despite significant progress in metasurface diffraction lenses, no single material yet been capable of constructing covering ultrabroad wavebands, including the visible near‐infrared (NIR), due to limitations bandgaps. This limitation complicates fabrication processes, integration, miniaturization, often leading instability. In this...
Conventional microscopes, which rely on multiple objective lenses for varying magnifications, are bulky, complex, and costly, making them difficult to integrate into compact devices. They require frequent manual adjustments, complicating the imaging process increasing maintenance burdens. This paper explores potential of single ultrathin graphene metalens address this issue. We propose demonstrate a 200 nm thin multiaxial focus with high-quality focusing, designed using spatial multiplexing...
Dual camera is becoming increasingly prevalent among smartphone schemes these days. This paper demonstrates a system prototype by using the color and monochrome cameras on one simultaneously for visible light communication. To achieve this, we propose novel dual-modulation scheme. The baseband signal firstly modulated ratio modulation-color shift keying (CRM-CSK) to broadcast information that can be distinguished camera. Next it, gray level modulation (GLM) utilized generate CRM symbols with...
ABSTRACT Every collected photon is precious in live-cell super-resolution (SR) fluorescence microscopy for contributing to breaking the diffraction limit with preservation of temporal resolvability. Here, maximize utilization accumulated photons, we propose SN2N, a S elf-inspired N oise 2N engine self-supervised data generation and self-constrained learning process, which an effective data-efficient learning-based denoising solution high-quality SR imaging general. Through simulations...
Lensless imaging based on multi-wavelength phase retrieval becomes a promising technology widely used as it has simple acquisition, miniaturized size and low-cost setup. However, measuring the sample-to-sensor distance with high accuracy, which is key for high-resolution reconstruction, still challenge. In this work, we propose criterion to realize autofocusing modulation, i.e., achieving much higher accuracy in determining distance, compared conventional methods. Three beams different...
An interleaved coding Janus metasurface is proposed, which can generate bidirectional functionalities with full phase control of the reflected and transmitted waves. By introducing rotation geometric parameter changes into meta-atoms, reflection transmission channels required energy distribution foci are realized. More remarkably, our approach based on a single design that arranges two types unidirectional propagating unit structures simultaneous desired properties checkerboard configuration...
Despite super-resolution fluorescence blinking microscopes break the diffraction limit, intense phototoxic illumination and long-term image sequences thus far still pose to major challenges in visualizing live-organisms. Here, we proposed a method based on auto-correlation two-step deconvolution (SACD) enhance temporal resolution at lower signal intensity levels. Unlike conventional techniques, such as optical fluctuation imaging (SOFI) or stochastic reconstruction microscopy (STORM), our...
The V-shaped toothed roller cotton stalk puller has a low removal ratio and weak pulling effect. Hence, we constructed simplified mathematical model of the tooth based on elastic collision theory simple beam conducted mechanical analysis this to explore causes errors fractures. Specifically, plates machine were optimized in an orthogonal experiment with rotational speed, cogging angle, ground clearance as influencing factors, evaluation index. This was designed enable physical...
In the oil field development and production, fluid flow is an extremely important parameter which determines transmission characteristics of real-time monitoring provides a scientific basis for gas optimization exploration increase reservoir recovery. A method interrogating fiber optic sensors using flow-induced pipe vibration proposed, measured non-intrusively, study conducted on induced by turbulent when through pipe. The frequency pipe's signals found,then fixed relationship between...
ABSTRACT In fluorescence microscopy, computational algorithms have been developed to suppress noise, enhance contrast, and even enable super-resolution (SR). However, the local quality of images may vary on multiple scales, these differences can lead misconceptions, which is especially intractable in emerging deep-learning ones. Current mapping methods fail finely estimate quality, challenging associate SR scale content. Here, we develop a rolling Fourier ring correlation (rFRC) framework...
ABSTRACT Super-resolution (SR) imaging with high-throughput is invaluable to fast and high-precision profiling in a wide range of biomedical applications. However, prevalent SR methods require sophisticated acquisition devices specific control, may cost fairly long time on single field-of-view. These essentially increase the construction difficulty, including challenges throughput, system establishment, automation. Using natural photophysics fluorescence, fluctuation-based microscopy...
Confocal microscopy has the advantages of high resolution and optical sectioning ability over conventional microscopy. However, aberration induced by system can compromise these considerably reduce energy reaching pointlike detector. We propose an accurate correction method with a liquid-crystal spatial light modulator (LCSLM) in confocal system. Each coefficient Zernike modes is calculated directly measuring variance images different bias modes. Large-coefficient (>0.7 rad) compensated...
In this work, based on fluorescence blinking and blench microscope systems, we proposed a super-resolution method auto-correlation two-step deconvolution (SACD) to enhance the temporal resolution at lower signal intensity levels, utilizing LR as two separated steps combining with multi-plan (MPAC). SACD model, time-varying images can be analyzed produce under insufficient frames involved or sparse photons level. By using three typical datasets, i.e., simulated fluctuation data, experimental...
A light-field endoscope can simultaneously capture the three-dimensional information of in situ lesions and enables single-shot quantitative depth perception with minimal invasion for improving surgical diagnostic accuracy. However, due to oversized rigid probes, clinical applications current techniques are limited by their cumbersome devices. To minimize size enhance flexibility, here we report a highly flexible compact volumetric employing precision-machined multiple micro-imaging devices...