- Child Nutrition and Feeding Issues
- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- Child Nutrition and Water Access
- Diet and metabolism studies
- Gastroesophageal reflux and treatments
- Nutritional Studies and Diet
- Adipose Tissue and Metabolism
- Inflammatory Bowel Disease
- Esophageal and GI Pathology
- Microscopic Colitis
- Body Composition Measurement Techniques
- Fibroblast Growth Factor Research
- Tissue Engineering and Regenerative Medicine
- Metallurgy and Material Science
- Dysphagia Assessment and Management
- Food Security and Health in Diverse Populations
- Asthma and respiratory diseases
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Respiratory and Cough-Related Research
- Dietary Effects on Health
- Celiac Disease Research and Management
- Frailty in Older Adults
- Regulation of Appetite and Obesity
Boston Children's Hospital
2015-2024
Harvard University
2023-2024
National Institutes of Health
2020
New Balance (United States)
2015-2017
In two separate cohorts, intestinal resection for Crohn's disease was associated with reduced alpha diversity and increased Proteobacteria Bacteroidetes Firmicutes.Surgery also decreased abundance of bai operon genes secondary bile acids, including isoLCA.
Objective To examine associations of baseline insulin dynamics with changes in body composition and resting energy expenditure (REE) following weight loss. Methods Twenty-one participants overweight or obesity achieved 10-15% loss then received 3 maintenance diets (high-carbohydrate, moderate-carbohydrate, low-carbohydrate) random order, each for 4 weeks. Body was measured at after Insulin 30 min glucose consumption (insulin-30; response), C-peptide deconvolution analysis, HOMA, hepatic...
The aim of the study was to quantify differences in viscosity over a range commercial food-based formulas and home-prepared blenderized feeds used for enteral feeding clinical management gastroesophageal reflux reflux-related aspiration children with oropharyngeal dysphagia.The home blends measured using digital rotational viscometer International Dysphagia Diet Standardization Initiative Syringe Flow Test. Additional testing performed determine impact added cereal, water flushes,...
We sought to characterize the effects of dietary macronutrient composition on various hormones implicated in regulation insulin sensitivity (IS) and energy expenditure (EE).Following 10-15% weight loss, 21 overweight subjects consumed 3 weight-loss maintenance diets [low fat (LF), low glycemic index (LGI) very carbohydrate (VLC)] random order, each for 4 weeks. At baseline at end treatment period, fasting samples fibroblast growth factor (FGF)-21, heme-oxygenase-1 (HO-1), chemerin, irisin,...
Abstract Background Nutrition screening on admission is critically important to systematically identify patients with undernutrition given the known relationship deleterious clinical outcomes. Limited data exist regarding optimal processes and criteria for pediatric nutrition screening. Therefore, we sought characterize practices in hospitals. Methods A total of 365 inpatient hospitals United States were identified, eligible, contacted. Eligible included general hospitals, adult units,...
Lifelong adherence to a gluten-free diet (GFD) is the primary treatment of celiac disease (CeD), gluten-driven enteropathy. Concerns have been raised about increased exposure arsenic from GFD because rice, which naturally bioaccumulates arsenic, commonly used as substitute for gluten-containing grains such wheat. We hypothesize that increases in newly diagnosed children with CeD after they adopt GFD.
Abstract Background Blenderized tube feeds (blends) are associated with lower hospital admissions and reduced gastroesophageal symptoms, but their high viscosity may theoretically prolong gastric emptying. Our objective was to compare differences in emptying blends vs formula. Methods We retrospectively identified individuals 6 months 20 years enteral tubes who underwent 1‐h liquid scintigraphy from 1998 2020 at Boston Children's Hospital. Examinations were excluded if a postpyloric present,...
Abstract Background The objective of this quality‐improvement project was to increase documentation rates anthropometrics (measured weight, length/height, and body mass index [BMI], which are critical identify patients at malnutrition (undernutrition) risk) from <50% 80% within 24 hours hospital admission for pediatric patients. Methods Multidisciplinary champion teams on surgical, cardiac, intensive care (ICU) pilot units were established iteratively test interventions addressing...