A5104883793- IL-33, ST2, and ILC Pathways
- Asthma and respiratory diseases
- Eosinophilic Esophagitis
- Sinusitis and nasal conditions
- Cancer-related molecular mechanisms research
- Herpesvirus Infections and Treatments
- Mesenchymal stem cell research
- Ferroptosis and cancer prognosis
- Antimicrobial Peptides and Activities
- Cervical Cancer and HPV Research
- Hematopoietic Stem Cell Transplantation
- Plant chemical constituents analysis
- Glycosylation and Glycoproteins Research
- Pediatric health and respiratory diseases
- Allergic Rhinitis and Sensitization
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Antimicrobial Resistance in Staphylococcus
- Studies on Chitinases and Chitosanases
- Neonatal Respiratory Health Research
- Microbial Natural Products and Biosynthesis
- Hematological disorders and diagnostics
- Periodontal Regeneration and Treatments
- Genomics, phytochemicals, and oxidative stress
- Teratomas and Epidermoid Cysts
China Medical University
2009-2025
Chinese PLA General Hospital
2023
University of Pittsburgh
2021-2022
University of Pittsburgh Medical Center
2019
Background Cutaneous melanoma is a type of malignant tumor that challenging to predict and readily stimulated by various factors. Oxidative stress can induce damage alterations in melanocytes, subsequently triggering immune responses. Given oxidative prevalent stimulus, we aimed enhance prediction identifying lncRNA signatures associated with stress. Methods We screened for stress-related lncRNAs could improve patient prognosis using the TCGA GTEx databases. Utilizing differentially...
Although type-2-induced (T2-induced) epithelial dysfunction is likely to profoundly alter differentiation and repair in asthma, the mechanisms for these effects are poorly understood. A role specific mucins, heavily N-glycosylated glycoproteins, orchestrating cell fate response T2 stimuli has not previously been investigated. Levels of a sialylated MUC4β isoform were found be increased airway specimens from asthmatic patients association with inflammation. We hypothesized that IL-13 would...
Secondary to war wounds, trauma, etc., hypertrophic scar formation is the cause of an excessive proliferation fibroblasts and accumulation collagen fibers, which might affect cosmetic appearance, could malignant transformation. miRNAs play important role in disease regulation via inhibiting post-transcriptional protein translation by targeting binding 3' UTR region mRNA. Here we explore mechanism interventions from perspective miRNA.Hypertrophic scar-associated differential were screened...
The aim of the present study was to investigate association between O6-methylguanine-DNA methyltransferase (MGMT) gene expression levels, and DNA methylation status histone modifications in laryngeal squamous cell carcinoma (LSCC). Chromatin immunoprecipitation, methylation-specific polymerase chain reaction (PCR), reverse transcription-quantitative PCR were performed analyze modifications, mRNA levels promoter region MGMT HEp-2 cells, as well 50 paired healthy LSCC tissue samples....
Chronic rhinosinusitis with nasal polyps (CRSwNP) is connected to a chronic inflammatory process the activation of different immune components. Eotaxin‐3, acidic mammalian chitinase (AMCase), and interleukin (IL)–13 as focal factors have been detected in CRSwNP, but their importance relationship are still being investigated. This study aims detect expression AMCase, IL‐13, eotaxin‐3 mRNA level investigate roles relationships CRSwNP. Twenty‐four subjects eosinophilic CRSwNP 11 controls were...