A5108833152- Antioxidant Activity and Oxidative Stress
- Photosynthetic Processes and Mechanisms
- Plant biochemistry and biosynthesis
- Ubiquitin and proteasome pathways
- COVID-19 Clinical Research Studies
- Cervical Cancer and HPV Research
- Real-time simulation and control systems
- Asymmetric Hydrogenation and Catalysis
- Plant Gene Expression Analysis
- Asymmetric Synthesis and Catalysis
- Advanced Proteomics Techniques and Applications
- Plant Stress Responses and Tolerance
- Higher Education and Teaching Methods
- Machine Fault Diagnosis Techniques
- Genetic and Kidney Cyst Diseases
- Glycosylation and Glycoproteins Research
- Transportation Systems and Logistics
- Fault Detection and Control Systems
- Sensorless Control of Electric Motors
- IoT-based Smart Home Systems
- Wireless Power Transfer Systems
- Superconductivity in MgB2 and Alloys
- Optimization and Search Problems
- E-commerce and Technology Innovations
- SARS-CoV-2 detection and testing
Shanghai Jiao Tong University
2023-2024
Henan University
2024
Beijing Proteome Research Center
2020-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2023
Shanghai Changzheng Hospital
2023
Northwestern Polytechnical University
2021-2023
Chongqing Medical University
2021-2023
Yangtze River Delta Physics Research Center (China)
2022
Academy of Military Medical Sciences
2022
Kunming University of Science and Technology
2022
Abstract Asymmetric sequential hydrogenations of α ‐methylene γ ‐ or δ ‐keto carboxylic acids are established in one‐pot using a bimetallic Ru/Ru catalyst system, achieving the stereodivergent synthesis all four stereoisomers both chiral and ‐lactones with two non‐vicinal carbon stereocenters high yields (up to 99%) excellent stereoselectivities >99% ee >20:1 dr). The compatibility Ru systems is investigated detail, it found that basicity reaction system plays key role hydrogenation...
The atypical pneumonia (COVID-19) caused by SARS-CoV-2 is a serious threat to global public health. However, early detection and effective prediction of patients with mild severe symptoms remain challenging. proteomic profiling urine samples from healthy individuals, COVID-19 positive comorbidities can be clearly differentiated. Multiple pathways have been compromised after the infection, including dysregulation complement activation, platelet degranulation, lipoprotein metabolic process...
It is of great importance to combine stress tolerance and plant quality for breeding research. In this study, the role phytoene desaturase (PDS), ζ-carotene (ZDS) carotene isomerase (CRTISO) in carotenoid biosynthesis are correlated compared. The three genes were derived from Lycium chinenses involved desaturation tetraterpene. Their over-expression significantly increased accumulation enhanced photosynthesis salt transgenic tobacco. Up-regulation almost all pathway only significant...
Abstract The RuPHOX‐Ru catalyzed asymmetric hydrogenation of diaryl ketones has been established, providing the corresponding chiral methanols in up to 99% yield and ee. protocol could be performed on a gram‐scale with relatively low catalyst loading (2000 S/C) resulting products allow for several useful transformations, particular synthesis drugs, such as, ( S )‐Orphenadrine )‐Neobenodine. Deuterium labeling control experiments revealed that RuPHOX‐Ru‐catalyzed is fully subject H 2 as sole...
SUMMARY The atypical pneumonia (COVID-19) caused by SARS-CoV-2 is an ongoing pandemic and a serious threat to global public health. COVID-19 patients with severe symptoms account for majority of mortality this disease. However, early detection effective prediction mild remains challenging. In study, we performed proteomic profiling urine samples from 32 healthy control individuals 6 positive (3 3 severe). We found that proteome the comorbidities can be clearly differentiated based on...
A RuPHOX/Pd catalyzed asymmetric allylic substitution cascade of α-carbonylamides with an meso -dicarbonate has been developed, providing chiral 3-acyl bicyclolactams in high yields and up to 99% ee >20 : 1 dr.
Lycium barbarum contains high levels of zeaxanthin, which is produced by the conversion -carotene into zeaxanthin. -Carotene hydroxylase catalyzes this reaction. We cloned a cDNA (chyb) encoding (Chyb) from L. leaf. A 939-bp full-length sequence was determined with 3′-rapid amplification end assay deduced Chyb protein (34.8 kDa) theoretical isoelectric point 8.36. bioinformatics analysis showed that located in chloroplast. Further, to investigate catalytic activity Chyb, complementation...
Sterol homeostasis is tightly controlled by molecules that are highly conserved from yeast to humans, the dysregulation of which plays critical roles in development antifungal resistance and various cardiovascular diseases. Previous studies have shown sterol regulated ubiquitin–proteasome system. Two E3 ubiquitin ligases, Hrd1 Doa10, known mediate proteasomal degradation 3-hydroxy-3-methylglutaryl-CoA reductase Hmg2 squalene epoxidase Erg1 with accumulation toxic sterols cells, but...
The recent breakthrough in understanding the etiology of cervical cancer has led to increased attention towards prevention and treatment this disease. Extensive research confirmed a strong correlation between persistent infection human papillomavirus (HPV) development cancer. Focusing on pivotal role HPV occurrence progression cancer, there been surge aimed at developing drugs that can eradicate reverse precancerous lesions. Natural have attracted considerable field tumor therapy due their...
The classical PID control does not consider the external disturbance and uncertain parameters of system which accuracy cannot meet requirements. Based on mathematical model three-stage generator, this paper adopts algorithm current inner loop regulation based exciter model, voltage outer load generator model. controller is designed by combining adaptive with backstepping then simulation built in Simulink for verification. results show that has better dynamic performance, damping stability...
The design unit was analyzed and the internal information of it encoded. At same time, dimension model constructed. matching constraint is used as search method, direction relative to determined, size in extracted, propagation chain constructed according association rules methods. Correlation formulated by number constraints, formulas, economic costs, processing difficulty criterion correlation strength. dimension-related accomplished using drive variants. Finally, an example verify...
As important secondary power supply equipment in aircraft system, the normal operation of transformer rectifier unit is great significance for safe aircraft. Taking as research object, paper has completed diode fault analysis and characteristic parameter extraction. First all, simulation was carried out two kinds abrupt faults short-circuit open-circuit TRU. By comparing different characteristics diodes at positions under types, parameters with obvious changes such effective value amplitude...
As the main secondary energy of more/all electric aircraft (MEA/AEA), power supply has unique advantages in weight, volume, reliability and maintainability compared with other such as hydraulic pneumatic energy, which makes it more widely used warships rapidly developing aircraft. At same time, order to make system meet requirements special high-power loads future, improve carrying capacity distribution adaptability system, grid-connected control strategy multiple generation systems will be...