A5001718215- Hearing Loss and Rehabilitation
- Hearing, Cochlea, Tinnitus, Genetics
- Multisensory perception and integration
- Neuroscience and Music Perception
- Hearing Impairment and Communication
- Noise Effects and Management
- Assistive Technology in Communication and Mobility
- Infant Health and Development
- RNA regulation and disease
- Medical Practices and Rehabilitation
- Ear Surgery and Otitis Media
- Tracheal and airway disorders
- Health, Education, and Physical Culture
- Phonetics and Phonology Research
- RNA and protein synthesis mechanisms
- Orthopedic Infections and Treatments
- Language Development and Disorders
- Color perception and design
- Tactile and Sensory Interactions
- Speech and Audio Processing
Sorbonne Paris Cité
2020
Université Paris Cité
2020
Hôpital Necker-Enfants Malades
2020
Assistance Publique – Hôpitaux de Paris
2020
Significance Presbycusis, or age-related hearing loss, is a major public health issue and the principal potentially modifiable risk factor for dementia. It caused by environmental factors largely uncharacterized genetic factors. We compared DNA sequences across genomic coding regions between familial sporadic cases of severe presbycusis controls with normal hearing. The frequency ultrarare predicted pathogenic variants in genes known to cause dominant early-onset forms deafness was...
Cochlear implants may improve the medical and social prognosis of profound deafness. Nevertheless, some patients have experienced poor results without any clear explanations. One correlate be an alteration in cortical voice processing. To test this hypothesis, we studied activation human temporal areas (TVA) using a well-standardized PET paradigm adapted from previous functional MRI (fMRI) studies. <b>Methods:</b> A H<sub>2</sub><sup>15</sup>O study was performed on 3 groups adult...
Age at implantation is considered to be a major factor, influencing outcomes after pediatric cochlear implantation. In the absence of acoustic input, it has been proposed that cross-modal reorganization can detrimental for adaptation new electrical input provided by implant. Here, through retrospective study, we aimed investigate differences in cerebral blood flow (CBF) rest prior children with congenital deafness compared normally hearing children. addition, looked putative link between...
CEA-Inserm U1000 Neuroimaging and Psychiatry, Service Hospitalier Frederic Joliot, Orsay, France, CEA, DRM, DSV, Frederic-Joliot, Laboratoire de Correction Auditive, Eric Bizaguet, Paris, Inserm, UMR-S 867, AP-HP, Hopital Beaujon, d’ORL et Chirurgie cervico-faciale, Clichy, Universite Paris 7 Denis Diderot, Louis Mourier, Colombes, Pitie-Salpetriere, Urgences cerebro-vasculaires, 6 Pierre Marie Curie, France
Purpose: Deafness in infancy has longlasting consequences on brain organization. To achieve the best developmental outcomes case of profound deafness, cochlear implantation (CI) needs to take place a critical period during first year life, before cross-modal reorganization due auditory deprivation stabilises, preventing typical development cortices. Despite its importance for outcomes, nature this and underlying neural have not been fully explored. Materials methods: fill knowledge gap, we...
La prise en charge du patient atteint d’un acouphène chronique invalidant devrait être pluridisciplinaire. Parmi les intervenants, l’audioprothésiste tient une place très importante. Notre prothétique de l’acouphène a beaucoup évolué au long ces dernières années et ce travail présente résultats obtenus avec masqueurs, atténuateurs son ainsi qu’avec d’autres réalisations apparentées. Les meilleurs sont des appareils correcteurs la surdité. principes l’adaptation diffèrent selon que perte...