A5103069961- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Air Quality Monitoring and Forecasting
- Noise Effects and Management
- Energy and Environment Impacts
- Indoor Air Quality and Microbial Exposure
- Environmental Justice and Health Disparities
- Asthma and respiratory diseases
- Occupational exposure and asthma
- Vehicle emissions and performance
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inhalation and Respiratory Drug Delivery
- Energy, Environment, and Transportation Policies
- Urban Transport and Accessibility
- Nutritional Studies and Diet
- Traffic and Road Safety
- Fatty Acid Research and Health
- Neuroendocrine regulation and behavior
- Health disparities and outcomes
- Food Security and Health in Diverse Populations
- COVID-19 impact on air quality
- Stress Responses and Cortisol
- Heart Rate Variability and Autonomic Control
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Child Nutrition and Water Access
University of Colorado Denver
2017-2022
University of Pittsburgh Medical Center
2009-2017
University of Pittsburgh
2010-2016
UPMC Montefiore
2013-2015
Public Health Department
2012
Emory University
2003-2008
Centers for Disease Control and Prevention
2004-2008
Instituto Nacional de Salud Pública
2003-2005
Université Laval
2005
The biological mechanisms involved in inflammatory response to air pollution are not clearly understood.In this study we assessed the association of short-term pollutant exposure with markers and lung function.We studied a cohort 158 asthmatic 50 nonasthmatic school-age children, followed an average 22 weeks. We conducted spirometric tests, measurements fractional exhaled nitric oxide (Fe(NO)), interleukin-8 (IL-8) nasal lavage, pH breath condensate every 15 days during follow-up. Data were...
Background: Suspended particles and ozone have been associated with varying degrees of cardiac autonomic dysfunction Methods: In Mexico City, residents from a nursing home underwent heart rate variability analysis every other day for 3 months. Indoor outdoor PM2.5 (particulate matter less than 2.5 mm in diameter) were measured daily at the home. Levels atmospheric pollutants obtained nearby automated monitoring station. Results: Of initial 42 screened participants, 34 (81%) followed during...
Rationale: Traffic-related emissions have been associated with respiratory symptoms in some studies. However, there is limited information on how traffic-related relate to lung function and airway inflammation.Objectives: To determine the differential association of exposures exhaled nitric oxide (NO) volumes children without asthma.Methods: We performed a longitudinal study 200 from ages 6 12 years whom half had physician-diagnosed asthma. Two-week NO2 48-hour average levels elemental...
In the United States, among Hispanics, Mexican Americans have lowest rate of asthma. However, this population includes born in States and Mexico, risk factors that might impact prevalence asthma differ between these groups. To determine for U.S.- Mexican-born Americans, we analyzed data from two U.S. surveys included 4,574 persons who self-reported their ethnicity as American Third National Health Nutrition Examination Survey (NHANES III) 1998-1994 12,980 Interview (NHIS) 1997-2001....
Context: Environmental exposure to particulate matter of 2.5 μm or less (PM2.5) has been associated with changes in heart rate variability (HRV).Objective: To evaluate the effect supplementation omega-3 polyunsaturated fatty acids on reduction HRV PM2.5 exposure.Design: Randomized double-blind trial.Setting: Mexico City, Mexico.Participants: 50 nursing home residents older than 60 yr.Intervention: Randomization either 2 g/d fish oil versus soy as control, 6 mo follow-up (1-mo...
Exposure to fine airborne particulate matter [< or =2.5 microm in aerodynamic diameter (PM(2.5))] has been associated with cardiovascular and hematologic effects, especially older people disease. Some epidemiologic studies suggest that adults diabetes also may be a particularly susceptible population.The purpose of this study was analyze the short-term effects ambient PM(2.5) on markers endothelial function diabetic volunteers.We conducted prospective panel 22 type 2 mellitus Chapel Hill,...
BackgroundThe mechanisms of particulate matter (PM)-induced health effects are believed to involve inflammation and oxidative stress. Increased intake omega-3 polyunsaturated fatty acids (n-3 PUFA) appears have anti-inflammatory effects.ObjectiveAs part a trial evaluate whether n-3 PUFA supplementation could protect against the cardiac alterations linked PM exposure, we measured biomarkers response stimuli [copper/zinc (Cu/Zn) superoxide dismutase (SOD) activity, lipoperoxidation (LPO)...
Background: Concerns regarding the health impact of urban air pollution on asthmatic children are pronounced along U.S.–Mexico border because rapid population growth near busy highways and roads.Objectives: We conducted first binational study impacts in Ciudad Juarez, Mexico, El Paso, Texas, USA, compared different exposure metrics to assess acute respiratory response.Methods: recruited 58 from two schools Juarez Paso. A marker airway inflammation [exhaled nitric oxide (eNO)], symptom...
While air pollution exposures have been linked to cardiovascular outcomes, the contribution from acute gas and particle traffic-related pollutants remains unclear. Using a panel study design with repeated measures, we examined associations between personal in Mexico City changes heart rate variability (HRV) population of researchers aged 22 56 years. Participants were monitored for approximately 9.5 hours eight days while operating mobile laboratory van designed characterize traffic driving...
Impacts of industrial emissions on outdoor air pollution in nearby communities are well-documented. Fewer studies, however, have explored impacts indoor quality these communities. Because persons northern climates spend a majority their time indoors, understanding exposures, and the role shaping such is priority issue. Braddock Clairton, Pennsylvania, near Pittsburgh, home to an active steel mill coke works, respectively, population experiences elevated rates childhood asthma. Twenty-one...
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Because fine particulate matter (PM2.5) differs in chemical composition, source apportionment is frequently used for identification of relative contributions multiple sources to outdoor concentrations. Indoor air pollution and often overlooked, though people northern climates may spend up 90% their time inside. We selected 21 homes a 1-week indoor sampling session during summer (July September 2011), repeated winter (January March 2012). Elemental analysis was performed using...