- Acute Ischemic Stroke Management
- Cancer Research and Treatments
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Cerebrovascular and Carotid Artery Diseases
- Digital Holography and Microscopy
- Peptidase Inhibition and Analysis
- Glycosylation and Glycoproteins Research
- Neurological Complications and Syndromes
- Cell Image Analysis Techniques
- Intracerebral and Subarachnoid Hemorrhage Research
- Systemic Lupus Erythematosus Research
- Moyamoya disease diagnosis and treatment
- Diabetes Treatment and Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Cerebral Venous Sinus Thrombosis
- Pancreatic and Hepatic Oncology Research
- Stroke Rehabilitation and Recovery
- Vestibular and auditory disorders
- PARP inhibition in cancer therapy
- Neuropeptides and Animal Physiology
- Peripheral Neuropathies and Disorders
- Advanced Fluorescence Microscopy Techniques
- Cancer Cells and Metastasis
- Intracranial Aneurysms: Treatment and Complications
Hanyang University
2016-2025
Hanyang University Seoul Hospital
2011-2025
Wonkwang University
2013-2024
Anyang University
2016-2024
Dongnam Institute of Radiological & Medical Sciences
2024
Korea Advanced Institute of Science and Technology
2018-2023
Wonkwang University Medical Center
2023
Kootenay Association for Science & Technology
2022
Dankook University
2020-2021
Jeonbuk National University
2021
ABSTRACT T hermal and other physicochemical properties of starch from 42 potato genotypes were studied to find those with unique for food use, analyze relationships between thermal properties. Onset peak transition temperatures gelatinization enthalpy intercorrelated. Transition intercorrelated pasting temperature using a Brabender Visco‐amylograph. Gelatinization entbalpy correlated paste viscosity, onset phosphorus content. Genotype E55–3.5 highest also had viscosity. DSC might be useful...
Abstract Background Delayed arrival at hospital is one of the major obstacles in enhancing rate thrombolysis therapy patients with acute ischemic stroke. Our study aimed to investigate factors associated prehospital delay after stroke Korea. Methods A prospective, multicenter was conducted 14 tertiary hospitals Korea from March 2009 July 2009. We interviewed 500 consecutive who arrived within 48 hours. Univariate and multivariate analyses were performed evaluate influencing delay. Results...
Abstract Stilbenes are phytoalexins that become activated when plants stressed. These compounds exist in foods and widely consumed. Resveratrol is a grape‐derived stilbene, which possesses wide range of health‐promoting activities, including anticancer properties. Several other stilbenes structurally similar to resveratrol also available food, but their biological activities remain largely unknown. In this study, we compared the effects its natural derivatives pterostilbene, trans...
Human serum and hemoglobin-free erythrocyte membranes were found to contain a galactosyltransferase which catalyzes the transfer of galactose from UDP-galactose specific large small molecular weight acceptors. The requirements for enzyme activity be similar enzymes both sources. However, membrane-bound depended on detergent maximal activity. Mn(++) was an absolute requirement uridine nucleoside phosphates inhibitors. most effective acceptor glycoprotein containing N-acetylglucosamine...
We present a deep neural network to reduce coherent noise in three-dimensional quantitative phase imaging. Inspired by the cycle generative adversarial network, denoising was trained learn transform between two image domains: clean and noisy refractive index tomograms. The unique feature of this distinct from previous machine learning approaches employed optical imaging problem, is that it uses unpaired images. learned quantitatively demonstrated its performance generalization capability...
Recurrent ischemic stroke (RIS) is associated with increased mortality and poor outcomes. Therefore, secondary prevention critical for reducing the risk of recurrent stroke. Previous studies have found sex differences in factors patients first-ever stroke; however, results been inconsistent this study aimed to investigate whether there are significant clinical characteristics stroke.We retrospectively studied 787 after confirmation using magnetic resonance imaging (MRI) visiting a regional...
Secretory mucins play an important role in the cytoprotection of epithelial surfaces and are used as tumour markers a variety cancers. The MUC6 secretory mucin was originally isolated from gastric cDNA library. aim to determine specific type location gene expression wide range human adult fetal tissues. In situ hybridization, RNA analysis, immunohistochemistry were quantify localize expression. data obtained show that is highly expressed mucosa, duodenal Brunner's glands, gall bladder,...
Introduction Ductal adenocarcinoma of the pancreas has recently been suggested to arise from histologically identifiable ductal lesions known as pancreatic intraepithelial neoplasia (PanINs). Altered levels and patterns mucin gene expression have reported occur in epithelial cancers. Aim To examine pattern membrane-associated mucins, MUC3 MUC4, a mucin-associated carbohydrate tumor antigen, sialyl Lex, these precursor pancreas. Methodology A total 144 PanIN 85 cases were examined by using...
Abstract Autism spectrum disorders (ASD) represent neurodevelopmental characterized by social deficits, repetitive behaviors, and various comorbidities, including epilepsy. ANK2 , which encodes a neuronal scaffolding protein, is frequently mutated in ASD, but its vivo functions disease-related mechanisms are largely unknown. Here, we report that mice with Ank2 knockout restricted to cortical hippocampal excitatory neurons (Ank2-cKO mice) show ASD-related behavioral abnormalities juvenile...
The comprehensive genomic impact of ionizing radiation (IR), a carcinogen, on healthy somatic cells remains unclear. Using large-scale whole-genome sequencing (WGS) clones expanded from irradiated murine and human single cells, we revealed that IR induces characteristic spectrum short insertions or deletions (indels) structural variations (SVs), including balanced inversions, translocations, composite SVs (deletion-insertion, deletion-inversion, deletion-translocation composites), complex...
To date, no large study has been conducted to investigate baseline stroke awareness within a nationally representative sample of the Korean population.A total 1000 residents were randomly sampled according regional demographic characteristics and interviewed in person by trained interviewers. Structured, open-ended close-ended questions asked assess awareness.Among respondents, 62% reported at least 1 symptom 56% risk factor for questioning. Multivariate analysis revealed that completion ≥12...
VIP exerts a spectrum of effects as potent anti-inflammatory factor. In addition, increases expression MUC2, major intestinal secretory mucin. We therefore investigated the on promoter activity 5'-flanking region MUC2 gene. activated transcription in human colonic epithelial cells via cAMP signaling to ERK and p38. cAMP/Epac/Rap1/B-Raf was not involved reporter activation. Furthermore, activation independent many reported downstream effectors G protein-coupled receptors, such PKC, Ras, Raf,...