A5071497545- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Genetic factors in colorectal cancer
- Organ Transplantation Techniques and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Appendicitis Diagnosis and Management
- Anatomy and Medical Technology
- History of Medical Practice
- Biliary and Gastrointestinal Fistulas
- Central Venous Catheters and Hemodialysis
- Congenital Anomalies and Fetal Surgery
- Neuroendocrine Tumor Research Advances
- Esophageal and GI Pathology
- Surgical site infection prevention
- Multiple and Secondary Primary Cancers
- Colorectal Cancer Screening and Detection
- Colorectal and Anal Carcinomas
Istituto di Studi sul Mediterraneo (CNR - ISMed)
2022-2025
University of Catania
2013-2024
Ospedale Cannizzaro
2001-2023
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2007-2020
Ospedale G.F. Ingrassia
2019
Tecnologie Avanzate (Italy)
2006-2017
Czech Academy of Sciences, Institute of Microbiology
1989
Background: Whether to routinely or selectively use intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC) has been a controversial issue for many years. Many authors maintain that IOC decreases the rate of biliary complications such as bile duct injuries, leak, and missed common (CBD) stones. However, in contrast these claims, centers have opted perform LC without IOC. In this retrospective study, results series 1,100 LCs, all which involved major were performed IOC,...
Concanavalin A (ConA)‐induced hepatitis is an experimental model of human autoimmune induced in rodents by i.v. injection Con A. The disease characterized increase serum levels transaminases and massive immune infiltration the livers. Type 1, type 2, 17 cytokines play a pathogenic role development ConA‐induced hepatitis. To understand further immunoregulatory mechanisms operating regulation hepatitis, we have evaluated anti‐inflammatory pathway Nrf2/HO‐1/CO (Nuclear Factor E2‐related 2/Heme...
There is growing evidence that gut microbiota dysbiosis linked to the etiopathogenesis of nonalcoholic fatty liver disease (NAFLD), from initial stage until progressive steatohepatitis (NASH) and final cirrhosis. Conversely, probiotics, prebiotics, synbiotics have shown promise in restoring lowering clinical indicators a number both preclinical studies. Additionally, postbiotics parabiotics recently garnered some attention. The purpose this bibliometric analysis assess recent publishing...
Liver fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) in hepatic parenchyma and represents an intrinsic response to chronic injury, maintaining organ integrity when extensive necrosis or apoptosis occurs. Hepatic stellate cells (HSCs) are major cell type responsible for liver fibrosis. Following HSCs become activated transdifferentiate into myofibroblasts (MFBs) that lead intrahepatic ECM accumulation. In present study, we performed a meta‑analysis...
Purpose/aim: The appropriate staging of colorectal cancer requires at least 12 lymph nodes to be sampled. We evaluated whether node sampling (LNS) and ratio (LNR) can predict the prognosis stage II-III patients. Materials methods: This is a retrospective study on 432 patients classified in LNS ≥12 <12. Disease-free survival (DFS) was computed using Kaplan–Meier method. stratified III into 4 quartiles base LNR values. To determine optimal cut-off, receiver operating characteristic (ROC) curve...
The teaching of human anatomy is experiencing significant transformation. Particularly in recent years, incorporating new digital technologies has drastically changed the approach to education. Our bibliometric study aims investigate trends and issues from 2004 2024 related technology teaching. publication trend field steadily increased over peaking 2022 declining 2023. Despite limited statistics for 2024, we do not project an exponential increase publications. Co-citation analysis...
Background/Objectives: Colorectal cancer is the third most common worldwide, making lymph node recovery critical for treatment decisions and prognosis. The relationship between body mass index (BMI) number of nodes retrieved during laparoscopic open surgeries remains controversial. This study aimed to evaluate whether surgical approach BMI influence retrieval in colon surgeries. Methods: A retrospective analysis was conducted on 560 patients who underwent surgery at a single institution 2018...
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KCNMA1 is a gene located at 10q22 that encodes the pore-forming α-subunit of large-conductance Ca2+-activated K+ channel. down-regulated in gastric carcinoma tumors, through hypermethylation its promoter. In present study, we have evaluated expression levels both mouse model Colorectal Cancer (CRC) and human CRC samples. Additionally, epigenetic mechanisms regulation were investigated. We observed significant down-regulation CRC. No differences were, however, different TNM stages. also...
The association between hepatic hemangioma (HH) and focal nodular hyperplasia (FNH) or the FNH adenoma (HA) has been reported. authors report a case in which FNH, HH, HA simultaneously appear liver. A 25-year-old woman was admitted to Department of Surgery University Catania (Italy), after presenting pain right hypocondrium. No therapy with oral contraceptives, no pregnancy abnormalities laboratory tests were found. Ultrasonography computed tomography scans revealed four masses...
Totally implantable venous device (TIVD) are widely used for the treatment of patients requiring long-term chemotherapy, total parenteral nutrition and fluid replacement. Until today, many kinds complications have been reported in literature. We report an unusual case catheter fracture as a consequence pinchoff syndrome, discuss potential methods to avoid this complication its evolution. J. Surg. Oncol. 2000;73:172–173. © 2000 Wiley-Liss, Inc.