A5069645134- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal and GI Pathology
- Liver Disease and Transplantation
- Colorectal Cancer Treatments and Studies
- Abdominal Trauma and Injuries
- Pancreatitis Pathology and Treatment
- Appendicitis Diagnosis and Management
- Hepatitis B Virus Studies
- Biliary and Gastrointestinal Fistulas
- Amoebic Infections and Treatments
- COVID-19 and healthcare impacts
- Bariatric Surgery and Outcomes
- Congenital Anomalies and Fetal Surgery
- Cancer Genomics and Diagnostics
- Parasitic infections in humans and animals
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Innovations in Medical Education
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
Groote Schuur Hospital
2016-2025
University of Cape Town
2016-2025
Local Government Association
2024
Memorial Sloan Kettering Cancer Center
2023
Karolinska Institutet
2012-2022
Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie
2020-2022
Karolinska University Hospital
2012-2022
Washington University in St. Louis
2021
University of Birmingham
2020-2021
Institut de Virologie
2021
Colorectal cancer (CRC) is a leading cause of cancer-associated deaths with liver metastases developing in 25-30% those affected. Previous data suggest survival difference between right- and left-sided metastatic CRC, even though has higher incidence metastases. The aim the study was to describe patterns as function characteristics primary tumour different combinations disease.A retrospective population-based performed on cohort patients diagnosed CRC region Stockholm, Sweden during 2008....
Abstract Background This multicentre international randomized trial compared the impact of gadoxetic acid-enhanced magnetic resonance imaging (MRI), MRI with extracellular contrast medium (ECCM-MRI) and contrast-enhanced computed tomography (CE-CT) as a first-line method in patients suspected colorectal cancer liver metastases (CRCLM). Methods Between October 2008 September 2010, CRCLM were to one three modalities. The primary endpoint was proportion for whom further after initial required...
Stereotactic CT-Guided Percutaneous Microwave Ablation of Liver Tumors With the Use High-Frequency Jet Ventilation: An Accuracy and Procedural Safety StudyJennie Engstrand1, Grzegorz Toporek2, Piotr Harbut1, Eduard Jonas1, Henrik Nilsson1 Jacob Freedman1Audio Available | Share
Contemporary management of patients with synchronous colorectal cancer and liver metastases is complex. The aim this project was to provide a practical framework for care metastases, focus on terminology, diagnosis, management.This multiorganizational, multidisciplinary consensus. consensus group produced statements which focused management. Statements were refined during an online Delphi process, those 70 per cent agreement or above reviewed at final meeting. Iterations the report shared by...
The aims of this study were to use dynamic hepatocyte-specific contrast-enhanced MRI evaluate liver volume and function in cirrhosis, correlate the results with standard scoring models explore inhomogeneous distribution cirrhotic livers.10 patients cirrhosis 20 healthy volunteers, serving as controls, included. Hepatic extraction fraction (HEF), input relative blood flow mean transit time calculated on a voxel-by-voxel basis using deconvolutional analysis. Segmental total volumes well...
Approximately 25% of patients with colorectal cancer (CRC) will have liver metastases classified as synchronous or metachronous. There is no consensus on the defining time point for synchronous/metachronous, and prognostic implications thereof remain unclear. The aim study was to assess value differential detection at various points in a population-based patient cohort conduct literature review topic.All diagnosed CRC counties Stockholm Gotland, Sweden, during 2008 were included followed 5...
Abstract Purpose To assess the feasibility to use dynamic hepatocyte‐specific contrast‐enhanced MRI (DHCE‐MRI) as an imaging‐based liver function test, and compare two methods for deconvolutional analysis (DA) in healthy human subjects. Materials Methods T 1 ‐weighted DHCE‐MRI with contrast medium Gd‐EOB‐DTPA was performed 20 volunteers. DA using truncated singular value decomposition (TSVD) Fourier appended tail (FA+Tail). Hepatic extraction fraction (HEF) input relative blood flow (irBF)...
Despite a fast and potent growth of the future liver remnant (FLR), patients operated with associating partition portal vein ligation for staged hepatectomy (ALPPS) are at risk developing posthepatectomy failure. In this study, relation between volume function in ALPPS was studied using multimodal assessment.