A5030853609- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Acute Kidney Injury Research
- Supercapacitor Materials and Fabrication
- Cardiovascular Health and Disease Prevention
- Parathyroid Disorders and Treatments
- Advancements in Battery Materials
- Advanced battery technologies research
- Image Processing Techniques and Applications
- Chronic Kidney Disease and Diabetes
- Erythropoietin and Anemia Treatment
- Muscle and Compartmental Disorders
- Digital Holography and Microscopy
- Iron Metabolism and Disorders
- Angiogenesis and VEGF in Cancer
- Lipid metabolism and disorders
- Electrocatalysts for Energy Conversion
- Chronic Disease Management Strategies
- Advanced Photocatalysis Techniques
- Environmental remediation with nanomaterials
- Inflammatory Biomarkers in Disease Prognosis
- Infectious Diseases and Tuberculosis
- Psoriasis: Treatment and Pathogenesis
- Adrenal and Paraganglionic Tumors
- Abdominal Surgery and Complications
Shanghai Jiao Tong University
2016-2025
Renji Hospital
2016-2025
China International Science and Technology Cooperation
2025
Chongqing Medical University
2025
Children's Hospital of Chongqing Medical University
2025
Capital Medical University
2023
Sichuan University
2008-2023
Hubei Cancer Hospital
2015-2022
Shandong Provincial Hospital
2021-2022
Shandong First Medical University
2021-2022
The increasing concentration of antibiotics in natural water poses a significant threat to society’s sustainable development due pollution. Photocatalytic technology is an efficient and environmentally friendly approach environmental purification, offering great potential for addressing pollution attracting attention from scholars worldwide. TiO2, as representative semiconductor photocatalytic material, exhibits strong oxidation ability excellent biocompatibility. However, its wide band gap...
Background Several studies have suggested that urgent-start peritoneal dialysis (PD) is a feasible alternative to hemodialysis (HD) in patients with end-stage renal disease (ESRD), but the impact of modality on outcome, especially short-term complications, has not been directly evaluated. The aim current study was compare complications and outcomes PD HD ESRD patients. Methods In this retrospective study, who initiated urgently without pre-established functional vascular access or catheter...
IL-6 is a vital inflammatory factor in the peritoneal cavity of patients undergoing dialysis (PD). The present study examined effect trans-signaling on structural alterations membrane. We investigated whether epithelial-to-mesenchymal transition (EMT) process human mesothelial cells (HPMCs) and production proangiogenic factors were controlled by trans-signaling. Its role was detected mouse model. morphology HPMCs levels cytokines PD effluent also explored. Stimulation with soluble receptor...
Sirtuin3 (Sirt3) is a histone deacetylase involved in the regulation of many cellular processes. Sirt3 deficiency known to increase oxidative stress. Reactive oxygen species (ROS) promote degradation extracellular matrix and vascular smooth muscle cell (VSMC) apoptosis. Reducing stress by overexpression could have therapeutic potential for limiting thoracic aortic dissection (TAD) development. We hypothesized that risk TAD decreasing ROS elimination (Sirt3 OE ) provide an alternative option...
Calciphylaxis is a rare but life-threatening complication seen in dialysis patients. We report case with calciphylaxis and severe secondary hyperparathyroidism. Sodium thiosulfate (STS) was used for treatment this case. The painful skin ulcers improved significantly soon after treatment, slight reduction the calcium-phosphorus product. Total parathyroidectomy carried out 6 months STS therapy, which successfully solved hyperparathyroidism high profiles. Until now, no recurrence of has been...
Background Whether sarcopenic obesity had unfavorable effect on survival of peritoneal dialysis (PD) patients is unknown. We aimed to investigate the association between and in PD patients. Methods This was a prospective observational study. Eligible from November 2016 December 2017 were enrolled followed until August 31, 2023. Sarcopenia defined following recommendations Asian Working Group for (AWGS) as low appendicular skeletal muscle mass index (ASMI) handgrip strength (HGS). Obesity...
Background Peritoneal dialysis (PD)-related pleuroperitoneal communication is strongly associated with PD discontinuation. Video-assisted thoracoscopic surgery (VATS) has emerged as a promising therapeutic approach. However, there are still challenges in detecting diaphragmatic defects under conventional thoracoscopy, and the repair methods vary significantly. Methods We have developed an intervention protocol for that includes single-port VATS utilizing near-infrared fluorescence...
<b><i>Background:</i></b> To evaluate the association of dialysate interleukin-6 (IL-6), a marker ongoing peritoneal inflammation, with alteration solute transport rate (PSTR) in continuous ambulatory dialysis (CAPD) patients. <b><i>Methods:</i></b> Stable CAPD patients were enrolled present study. A total 128 analyzed this prospective IL-6 concentration overnight effluent was determined and expressed as appearance (IL-6AR). Mass transfer area...
Interleukin-6 (IL-6) is a vital inflammatory factor in the peritoneal cavity of dialysis (PD) patients. Because intraperitoneal inflammation closely associated with angiogenesis, we sought to explore effect IL-6 on vascular endothelial growth (VEGF) synthesis and its transduction pathway mesothelial cells.Human cells (Met-5A) were incubated different concentrations glucose mannitol, mannitol expression was determined. Then, stimulated by or without two soluble receptors (sIL-6R sgp130), VEGF...
Patients with end-stage renal disease (ESRD) frequently require urgent-start dialysis. Recent evidence suggests that peritoneal dialysis (PD) might be a feasible alternative to hemodialysis (HD) in these patients, including older patients.This retrospective study enrolled patients aged > 65 years ESRD who underwent urgent without functional vascular access or PD catheter at single center, from January 2011 December 2014. were grouped based on their modality (PD HD). unable tolerate insertion...
Abstract Aim This study investigated the associated factors of 6‐min walk test (6MWT) and its predictive value outcome in patients undergoing peritoneal dialysis (PD). Methods is a single centre prospective observational cohort study. Stable ambulatory PD our between 1 May 2010 30 April 2011 were enrolled this All included subjects performed 6MWT, distances (6MWDs) recorded. Patients divided into two groups according to 6MWD prospectively followed up until death, cessation or end (30...
Embryonic stem cells (ESCs) may be useful as a therapeutic source of for the production healthy tissue; however, they are associated with certain challenges including immunorejection well ethical issues. Induced pluripotent (iPSCs) promising substitute since patient's own adult would serve tissue precursors. Ethical concerns prevent full evaluation developmental potency human ESCs and iPSCs, therefore, mouse iPSC models required protocol development safety assessments. We used modified...
Abstract Peritoneal fibrosis is a common pathological response to long‐term peritoneal dialysis (PD) and major cause for PD discontinuation. Understanding the cellular molecular mechanisms underlying induction progression of great interest. In our study, in vitro study revealed that signal transducer activator transcription 3 (STAT3) key factor fibroblast activation extracellular matrix (ECM) synthesis. Furthermore, STAT3 induced by IL‐6 trans‐signalling pathway mediate fibroblasts stroma...
Introduction Our objective was to examine the factors associated with serum angiopoietin-2/angiopoietin-1 (Angpt-2/Angpt-1) ratio in peritoneal dialysis (PD) patients and investigate association between Angpt-2/Angpt-1 cardiovascular all-cause mortality.