A5033609356- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Surgical Treatments
- Gastrointestinal Tumor Research and Treatment
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Airway Management and Intubation Techniques
- Surgical Simulation and Training
- Diverticular Disease and Complications
- Water Treatment and Disinfection
- Intraperitoneal and Appendiceal Malignancies
- Foreign Body Medical Cases
- Appendicitis Diagnosis and Management
- Digital Mental Health Interventions
- Mobile Health and mHealth Applications
- Advanced Image and Video Retrieval Techniques
- Medical and Health Sciences Research
- Obstructive Sleep Apnea Research
- Genetic factors in colorectal cancer
University Hospital Ulm
2017-2025
Agroscope
2024
ETH Zurich
2024
Amt für Umwelt
2024
Universität Ulm
1991-2023
Anesthesiology and Surgical Oncology Research Group
2023
Ospedale Valduce
2020
International Ocean Discovery Program
2018
Klinikum rechts der Isar
2012-2016
LMU Klinikum
2016
Background Mobile health apps (MHA) have the potential to improve care. The commercial MHA market is rapidly growing, but content and quality of available are unknown. Instruments for assessment highly needed. Application Rating Scale (MARS) one most widely used tools evaluate MHA. Only few validation studies investigated its metric quality. No study has evaluated construct validity concurrent validity. Objective This evaluates validity, reliability, objectivity, MARS. Methods Data was...
INTRODUCTION: Endoscopic full-thickness resection (EFTR) is a powerful option for of colorectal lesions not amenable to conventional endoscopic resection. The device (FTRD) allows clip-assisted EFTR with single-step technique. We report on results large nationwide FTRD registry. METHODS: “German colonic registry” was created further assess efficacy and safety the System after approval in Europe. Data were analyzed retrospectively. RESULTS: Sixty-five centers contributed 1,178 procedures....
Acute non-variceal upper gastrointestinal bleeding (NVUGIB) is managed by standard endoscopic combination therapy, but a few cases remain difficult and carry high risk of persistent or recurrent bleeding. The aim our study was to compare first-line over-the-scope-clips (OTSC) therapy with treatment in these selected patients.We conducted prospective, randomised, controlled, multicentre (NCT03331224). Patients evidence acute NVUGIB rebleeding (defined as complete Rockall Score ≥7) were...
Background and study aims: While artificial intelligence (AI) shows high potential in decision support for diagnostic gastrointestinal endoscopy, its role therapeutic endoscopy remains unclear. Third space endoscopic procedures pose the risk of intraprocedural bleeding. Therefore, we aimed to develop an AI algorithm blood vessel detection. Patients Methods: Using a test dataset with 101 standardized video clips containing 200 predefined submucosal vessels, 19 endoscopists were evaluated...
Summary and Recommendation This statement conveys the European Society of Gastrointestinal Endoscopy (ESGE) position on use computer-aided detection (CADe) with artificial intelligence (AI) during colonoscopy for colorectal cancer (CRC) screening or surveillance. The ESGE is informed by BMJ Rapid initiative approach MAGIC Evidence Ecosystem Foundation; these include systematic reviews currently available evidence, supplemented microsimulation modeling patient values preferences, benefits...
Background Texture and color enhancement imaging (TXI) was recently proposed as a substitute for standard high definition white-light (WLI) to increase lesion detection during colonoscopy. This international, multicenter randomized trial assessed the efficacy of TXI in colorectal neoplasia. Methods Consecutive patients aged ≥ 40 years undergoing screening, surveillance, or diagnostic colonoscopies at five centers (Italy, Germany, Japan) between September 2021 May 2022 were enrolled. Patients...
Artificial intelligence (AI)-based systems for computer-aided detection (CADe) of polyps receive regular updates and occasionally offer customizable thresholds, both which impact their performance, but little is known about these effects. This study aimed to compare the performance different CADe on same benchmark dataset. 101 colonoscopy videos were used as benchmark. Each video frame with a visible polyp was manually annotated bounding boxes, resulting in 129 705 images. The then analyzed...
Dysregulated intestinal epithelial apoptosis initiates gut injury, alters the barrier, and can facilitate bacterial translocation leading to a systemic inflammatory response syndrome (SIRS) and/or multi-organ dysfunction (MODS). A variety of gastrointestinal disorders, including bowel disease, have been linked apoptosis. Similarly, hyperpermeability failure occur in critically ill patients, putting at center SIRS pathology. Regulation immune-modulatory functions ascribed...
Abstract Background Conventional endoscopic resection of lesions affecting the appendiceal orifice is difficult. Endoscopic full-thickness (EFTR) a novel technique in interventional endoscopy. As EFTR near associated with subtotal appendectomy, it remains unclear whether risk developing appendicitis increased. We conducted retrospective analysis involving treated by EFTR. Methods This was multicenter patients (n = 50) for between 2014 and 2019. The objective to evaluate occurrence...
Computer-aided detection (CADe) helps increase colonoscopic polyp detection. However, little is known about other performance metrics like the number and duration of false-positive (FP) activations or how stable a is.111 colonoscopy videos with total 1,793,371 frames were analyzed on frame-by-frame basis using commercially available CADe system (GI-Genius, Medtronic Inc.). Primary endpoint was FP per colonoscopy. Additionally, we parameters, including per-polyp sensitivity, per-frame first...
Abstract Physical stress is common in GI endoscopists, leading to musculoskeletal disorders. Considering the increasing complexity of interventional endoscopy with prolonged examination time, work-related disorders have come into focus. However, data on health German endoscopists are elusive. The aim this study was therefore investigate prevalence and consequences endoscopists. A 24-item questionnaire endoscopy-associated standardized pain assessment developed by an interdisciplinary team...
In gastroenterology a sufficient colon cleansing improves adenoma detection rate and prevents the need for preterm repeat colonoscopies due to invalid preparation. It has been shown that patient education is of major importance improvement cleansing.Objective this study was assess function an automated text messaging (short message service, SMS)-supported colonoscopy preparation starting 4 days before appointment.After preevaluation mobile phone usage in population relevance approach,...