A5100355972- Alcohol Consumption and Health Effects
- Marine Toxins and Detection Methods
- Marine and coastal ecosystems
- Liver Disease Diagnosis and Treatment
- Gut microbiota and health
- Environmental Toxicology and Ecotoxicology
- Protist diversity and phylogeny
- Immune Cell Function and Interaction
- Protein Hydrolysis and Bioactive Peptides
- Meat and Animal Product Quality
- Microbial Community Ecology and Physiology
- biodegradable polymer synthesis and properties
- Health disparities and outcomes
- Cannabis and Cannabinoid Research
- Forensic Toxicology and Drug Analysis
- Nicotinic Acetylcholine Receptors Study
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pharmacological Effects of Natural Compounds
- Microplastics and Plastic Pollution
- Ginseng Biological Effects and Applications
- Biochemical effects in animals
- Eicosanoids and Hypertension Pharmacology
- Research in Cotton Cultivation
- GDF15 and Related Biomarkers
- T-cell and B-cell Immunology
Institute of Oceanology
2017-2025
Chinese Academy of Sciences
2017-2025
South China Sea Institute Of Oceanology
2017-2025
Jinan University
2017-2025
First Affiliated Hospital of Jinan University
2009-2023
Shandong University of Traditional Chinese Medicine
2023
Zhejiang University
2022-2023
Northwest A&F University
2022
Second Affiliated Hospital of Zhejiang University
2022
South China University of Technology
2006-2021
Increasing level of inflammation and oxidative stress could lead to memory impairment. The purpose this study was determine the neuroprotective effects walnut peptides against deficits induced by lipopolysaccharide (LPS) in mice further explore underlying anti-inflammatory mechanisms LPS-elicited BV-2 cells. Results showed that protein hydrolysate (WPH) its low-molecular-weight fraction (WPHL) ameliorate LPS via normalizing inflammatory response brain, especially WPHL. Furthermore, 18 with...
Identifying the temporal trends of cirrhosis and liver cancer attributable to alcohol use in both past future can formulate control strategies.Data on from 1990 2019, including mortality disability-adjusted life year (DALY) rates were collected 2019 Global Burden Disease (GBD) study. To analyze trends, average annual percentage change (AAPC) was calculated, Bayesian age-period-cohort model applied.Deaths DALY increased by years, but age-standardized death rate (ASDR) declined or remained...
The Niemann-Pick type C2 (NPC2) protein is a small, soluble, lysosomal important for cholesterol and sphingolipid transport in the lysosome. immunological phenotype of NPC2-deficient mice was limited to an impaired thymic selection Vα14 natural killer T cells (NKT cells) subsequent reduction NKT periphery. remaining failed produce measurable quantities interferon-γ vivo vitro after activation with α-galactosylceramide. In addition, thymocytes splenocytes from were poor presenters endogenous...
More than 50% of American adolescents and adults report having used illicit drugs in their lifetime. We examined the association lifetime opiate cocaine use with reduced kidney function, albuminuria rapid function decline among urban-dwelling adults.Our prospective cohort included 2,286 Healthy Aging Neighborhoods Diversity across Life Span study participants who were community-dwelling residing Baltimore, MD. The predictive variables use, defined as opiates or crack/cocaine ≥5 times....
In the present study, purpose is to compare effect of water extraction and alkali-assisted on structural characteristics immunomodulatory activity polysaccharides from Fuzhuan brick tea (FBTPs). The results indicated that water-extracted FBTPs (W-FBTPs) alkali-extracted (A-FBTPs) had similar molecular weights but different monosaccharide compositions, which A-FBTPs a higher yield uronic acid groups corresponding galacturonic (GalA). Moreover, stronger ability promote phagocytic capacity,...
The diversity and spatial-temporal distribution of phytoplankton HAB species, contamination status oyster toxin, their sources were investigated in Jiangmen farming area based on morphological observation liquid chromatography-tandem mass spectrometry analysis. results revealed there 28 including 19 harmless two toxic species (Akashiwo sanguinea Karenia brevis), seven toxin-producing microalgae (Alexandrium pacificum, Dinophysis caudata, D. miles, fortii, Gonyaulax spinifera, Gymnodinium...
Okadaic acid (OA) is one of the most prevalent marine phycotoxin with complex toxicity, which can lead to toxic symptoms such as diarrhea, vomiting, nausea, abdominal pain, and gastrointestinal discomfort. Studies have shown that main affected tissue OA digestive tract. However, its mechanism not yet fully understood. In this study, we investigated changes occurred in epithelial microenvironment following exposure, including barrier gut bacteria. We found impaired cell junctions, mucus layer...
As emerging contaminants, microplastics (MPs) may pose a threat to human health. Their co-exposure with the widespread phycotoxin okadaic acid (OA), marine toxin known cause gastrointestinal toxicity, exacerbate health risk and raise public safety concern. In this study, toxicity mechanisms of MPs OA on intestinal microenvironment was explored using Caco-2 cells as model, which combined an in vitro fecal fermentation experiment. Our results showed that (80 μg/mL) (20 ng/mL) significantly...
Continuous epidural anesthesia is a classic method that widely used in abdominal surgery, labor analgesia, and postoperative analgesia. A long-term analgesic effect achieved by continuously injecting local anesthetics into the space through an catheter. However, insertion of catheters associated with various complications, such as total spinal anesthesia, nerve damage, bleeding, infection, catheter distortion difficult removal. We present case parturient woman who underwent vaginal delivery...
Abstract Alcohol intoxication causes serious diseases, whereas current treatments are mostly supportive and unable to remove alcohol efficiently. Upon consumption, is sequentially oxidized acetaldehyde acetate by the endogenous dehydrogenase aldehyde dehydrogenase, respectively. Inspired metabolism of alcohol, a hepatocyte‐mimicking antidote for through codelivery nanocapsules oxidase (AOx), catalase (CAT), (ALDH) liver, where AOx CAT catalyze oxidation acetaldehyde, while ALDH catalyzes...