A5045292117- Lymphoma Diagnosis and Treatment
- Diabetes Management and Research
- Diabetes Treatment and Management
- Chronic Lymphocytic Leukemia Research
- Cutaneous lymphoproliferative disorders research
- Chronic Myeloid Leukemia Treatments
- Acute Lymphoblastic Leukemia research
- Diabetes Management and Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Venous Thromboembolism Diagnosis and Management
- T-cell and Retrovirus Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Chronic Disease Management Strategies
- Acute Myeloid Leukemia Research
- CAR-T cell therapy research
- Cancer Treatment and Pharmacology
- Viral-associated cancers and disorders
- Nail Diseases and Treatments
- Multiple and Secondary Primary Cancers
- CNS Lymphoma Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Lung Cancer Treatments and Mutations
- Diabetes and associated disorders
- Atrial Fibrillation Management and Outcomes
- Chemotherapy-induced cardiotoxicity and mitigation
Takeda (United States)
2016-2024
Indira Gandhi Delhi Technical University for Women
2024
Millennium Engineering and Integration (United States)
2016-2022
Takeda (Japan)
2017-2020
York Hospital
2019
Sanofi (United States)
2011-2017
AstraZeneca (United States)
2017
Sanofi (Mexico)
2014-2016
Radiology Associates of Albuquerque
2014
Carrier (United States)
2014
Detailed information on the cost burden of atrial fibrillation (AF) is limited. To provide an up-to-date estimate national AF, we conducted a retrospective, observational cohort study using administrative claims from MarketScan Commercial and Medicare Supplemental research data bases, 2004 to 2006.Patients aged ≥20 years with ≥1 inpatient or ≥2 outpatient AF diagnoses in 2005 (first diagnosis=index) ≥12 months' enrollment before after index were selected. patients propensity score-matched...
Abstract BACKGROUND: Recent studies suggest that thromboprophylaxis is beneficial in preventing venous thromboembolism (VTE) cancer outpatients, but this not widely adopted because of incomplete understanding the contemporary incidence VTE and concerns about bleeding. Therefore, authors examined predictors ambulatory patients with bladder, colorectal, lung, ovary, pancreas, or gastric cancers. METHODS: Data were extracted from a large health care claims database commercially insured United...
It has been hypothesized that Sydenham's chorea, a major manifestation of rheumatic fever, may provide medical model for obsessive-compulsive disorder and associated conditions, such as Tourette's syndrome. Monoclonal antibody D8/17 identifies B lymphocyte antigen with expanded expression in nearly all patients fever is thought to be trait marker susceptibility this complication group A streptococcal infection. The authors investigated whether greater than normal some forms syndrome.By...
In this paper, a detailed implementation of lithium-ion battery life prognostic system using particle filtering framework is presented. A lumped parameter model used to account for all the dynamic characteristics battery: non-linear open-circuit voltage, current, temperature, cycle number, and time-dependent storage capacity. The internal processes are form basis model. Statistical estimates noise in anticipated operational conditions processed provide remaining useful life. then...
To investigate treatment patterns and achievement of glycemic targets in patients with type 2 diabetes mellitus treated basal insulin a real-world setting, to determine physicians' beliefs practices regarding these patients.This study had two components; retrospective analysis using US claims database patient data, survey practices.A total 39,074 were included this analysis. The proportion achieving HbA1c<7.0% (53mmol/mol) was similar ongoing users at baseline (26%) 3months follow-up (27%)....
Summary First‐line treatments for classical Hodgkin lymphoma ( HL ) include ABVD (adriamycin, bleomycin, vinblastine, dacarbazine) and BEACOPP escalated (escalated dose etoposide, adriamycin, cyclophosphamide, vincristine, procarbazine, prednisone). To further improve overall outcomes, positron emission tomography‐driven strategies or variants incorporating the antibody‐drug conjugate brentuximab vedotin BV anti‐ PD 1 antibodies are under investigation in advanced‐stage patients. The present...
Brentuximab vedotin was approved for adult patients with CD30-expressing cutaneous T-cell lymphoma treated prior systemic therapy based on improved response rates and progression-free survival brentuximab (1.8 mg/kg once every 3 weeks; ≤16 cycles) versus physician's choice (methotrexate/bexarotene; ≤48 weeks) in the phase III ALCANZA study. Quality of life (QoL) also examined.QoL measures were Skindex-29, Functional Assessment Cancer Therapy-General (FACT-G) European QoL 5-dimension (EQ-5D)...
Clinical trials and community-based studies often include the Center for Epidemiologic Studies-Depression scale (CES-D) as a measure of depression outcome. We compared responses to symptom-related items on CES-D by depressed stroke primary-care patients several purposes: 1) illustrate use Item Response Theory (IRT)-based (Rasch) models comparing functioning across different patient subgroups; 2) inform clinicians outcome researchers about depressive symptomatology in stroke- with primary...
Aim: The Glycemic Effect in Diabetes Mellitus: Carvedilol–Metoprolol Comparison Hypertensives (GEMINI) trial compared the metabolic effects of two β‐blockers people with type 2 diabetes and hypertension treated renin–angiotensin system (RAS) blockade found differences outcomes. In this paper, we report results a prespecified secondary analysis GEMINI that sought to determine effect these on commonly reported symptoms. Methods: Symptom Checklist (DSC), self‐report questionnaire measuring...
Brentuximab vedotin (BV) is an anti-CD30 antibody-drug conjugate licensed for the treatment of relapsed/refractory Hodgkin lymphoma (rrHL) following autologous stem cell transplant (ASCT) or at least two prior therapies when ASCT multiagent chemotherapy not option. The objective this study was to describe real-world outcomes with BV in patients rrHL considered ineligible who refuse ASCT.This a retrospective medical chart review that enrolled ≥18 years old were initially diagnosed HL between...
Many patients with type 2 diabetes do not reach glycemic goals despite basal insulin treatment. This study assessed the achievement of a target A1C <7.0% (<53 mmol/mol) after initiation in two settings.This was retrospective analysis pooled randomized controlled trial (RCT) data, from 11 24-week studies initiating performed between 2000 and 2005 outpatient electronic medical record (EMR) data General Electric Centricity database for insulin-naive 2012. Baseline characteristics stratified by...
This study aimed to describe patient and caregiver preferences for treatments of relapsed or refractory multiple myeloma (MM).A survey including discrete-choice experiment (DCE) best-worst scaling (BWS) exercises was conducted among US patients with MM their caregivers. The DCE included six attributes varying levels progression-free survival (PFS), toxicity, mode frequency administration. In addition, the impact treatment cost assessed using a fixed-choice question. BWS exercise 18 items...
Abstract Learning Objectives After completing this course, the reader will be able to: Identify prevalence of adjuvant chemotherapy utilization in elderly patients with stage III colon cancer.Discuss and impact venous thromboembolism cancer.Identify potential for development a clinical trial to study benefit on cancer-specific all-cause mortality thromboprophylaxis during cancer. CME This article is available continuing medical education credit at CME.TheOncologist.com Background. The...
This retrospective study compared effectiveness of (brentuximab vedotin) BV to other chemotherapies in patients with rrHL following an autologous stem cell transplant (ASCT). Data originated from a medical chart review treated real-world clinical settings at 50 sites the United Kingdom and Germany. Inverse probability treatment weights based on propensity scores were used adjust for differences baseline characteristics between groups. Among 312 included, 196 received 116 physicians' choice...
ObjectivesTo develop and validate algorithms to define statin intolerance (SI) in an administrative database using electronic medical records (EMRs) as the reference comparison.MethodsOne thousand adults with one or more qualifying changes therapy previous diagnoses of hyperlipidemia, hypercholesterolemia, mixed dyslipidemia were identified from Henry Ford Health System database. Data regarding utilization, comorbidities, adverse effects extracted corresponding EMR. Patients stratified by...
The treatment pattern of cutaneous T-cell lymphoma (CTCL) remains diverse and patient-tailored. objective this study was to describe the patterns outcomes in CTCL patients who were refractory or had relapsed (R/R) after a systemic therapy. A retrospective chart review conducted at 27 sites France, Germany, Italy, Spain United Kingdom (UK) received first course therapy refractory. Data collected longitudinally from diagnosis first-, second- third-line included 157 patients, with median...
Aim: Forty percent of patients with higher-risk myelodysplastic syndromes (HR-MDS) transform to acute myeloid leukemia (AML). Materials & methods: This retrospective study assessed the impact HR-MDS transformation AML on OS in a 6-month landmark analysis and results were validated using time-varying analysis. Results: The rate was 26.9% at 1 year. Patients who transformed had higher risk death than did not (HR: 1.82; p: 0.0072) year 2.85; p < 0.0001). treated azacitidine decitabine...
Background. Patient education has long been recognized as a component of effective diabetes management, but the impact counseling and (C/E) interventions on health care costs is not fully understood. Objectives. To identify incidence type C/E received by 2 patients to evaluate associated economic clinical outcomes. Methods. This retrospective cohort study used Premier-Optum Continuum Care database (2005–2009) compare adult with receiving those (control). The index date was first or, in...
Purpose The purpose of this study is to examine outcomes in adult patients with type 2 diabetes mellitus who received counseling and education (C/E) services compared those did not. Methods A matched, retrospective cohort 17 483 C/E recipients 470 non-C/E controls was followed for up 12 months. Outcomes included glycemic control (glycosylated hemoglobin A1C levels <7.0%), hypoglycemic events, health care utilization costs. Results Compared the group, group had significantly lower (7.7% vs...