A5039022622- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiomyopathy and Myosin Studies
- Liver Disease Diagnosis and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- GDF15 and Related Biomarkers
- Cardiovascular Effects of Exercise
- Liver Disease and Transplantation
- Nutrition and Health in Aging
- Kidney Stones and Urolithiasis Treatments
- COVID-19 Clinical Research Studies
- Systemic Sclerosis and Related Diseases
- Macrophage Migration Inhibitory Factor
- Mechanical Circulatory Support Devices
- Eosinophilic Disorders and Syndromes
- Neurological disorders and treatments
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Dermatological and Skeletal Disorders
- Cardiac Arrhythmias and Treatments
- Cardiovascular Issues in Pregnancy
- Lysosomal Storage Disorders Research
- Viral Infections and Immunology Research
- Parathyroid Disorders and Treatments
- Sarcoidosis and Beryllium Toxicity Research
Universidade Federal Fluminense
2018-2025
Sociedade Brasileira de Cardiologia
2021
Hospital Pró-Cardíaco
2020
Hospital Universitário Antônio Pedro
2020
1. Introdução Nos últimos anos, foram consolidados avanços expressivos no conhecimento de amiloidose cardíaca (AC), trazendo uma profunda reformulação do seu significado clínico. Além haver evidências convincentes que AC seja causa relativamente comum insuficiência com fração ejeção preservada (ICFEP), assistimos o surgimento terapias específicas modificadoras curso natural da doença, capazes prolongar a sobrevida dos pacientes acometidos. Em paralelo, relevantes progressos nas técnicas...
Growth differentiation factor-15 (GDF-15) is a cytokine upregulated in multiple pathological conditions where oxidative stress, endothelial dysfunction, tissue aging, and chronic inflammation are the hallmarks. GDF-15 has many sources of production, including cardiac vascular myocytes, cells, adipocytes macrophages response to metabolic oncogenic transformation burden proinflammatory cytokines or reactive oxygen species. Although main extracardiac tissues, it been shown be elevated...
Resumo Fundamento Há uma falha em se identificar pacientes com insuficiência cardíaca (IC) um risco aumentado de hospitalização e morte. O Fator Diferenciação Crescimento-15 (GDF-15), biomarcador associado inflamação estresse oxidativo, surge como candidato a doença renal cardiovascular. Valores baixos taxa filtração glomerular estimada (TFGe), Sódio Urinário (NaU), valores altos da relação albumina/creatinina urinária são marcadores renais já associados alto internação hospitalar...
Abstract Background There is a lack in identifying heart failure (HF) patients with an increased risk of hospitalization and death. Growth differentiation factor 15 (GDF-15), biomarker associated inflammation oxidative stress, emerges as candidate cardiovascular renal disease. The low estimated glomerular filter rate (eGFR), urinary sodium (UNa), the high ratio albumin to creatinine are markers already mortality. Objective To evaluate relationship between GDF-15 chronic HF. Method We...
Abstract Background Renal function predicts events in chronic heart failure (HF). Urea to creatinine ratio (UCR) is a simple and cheap biomarker which correlates with neuroendocrine pathways. Objectives Evaluate the prognostic role of UCR patients HF. Methodology 86 HF from an academic hospital were included (with reduced, mildly reduced or improved left ventricular ejection fraction). was calculated at baseline, followed for median 360 (interquartile range 180-472) days. We plotted ROC...
The MAGGIC risk score has been validated to predict mortality in patients with heart failure (HF).
Longevity, combined with a higher prevalence of obesity, particularly visceral has been associated an increased risk cardiovascular diseases. Insulin resistance (IR) is important link between obesity and An association found sagittal abdominal diameter, IR. The objective this study to evaluate diameter as marker correlate it IR in older primary health care patients.
Transient elastography is a noninvasive method for assessing liver stiffness (LS), which can reflect right-sided filling pressure associated with passive congestion in patients HF.
Introduction Heart failure (HF) can be a serious disease if not treated properly. One of the markers severity is precisely hospitalization due to HF, often called acute HF or acutely decompensated (ADHF). ADHF involves patients with new an exacerbation chronic HF. The most common symptoms and signs in are dyspnea edema lower limbs. Dyspnea, when it occurs isolation, no specific hinder diagnosis. In this context, [...]
Background: Hepatic congestion is a frequent finding in patients with heart failure (HF). Physical examination has limitations quantifying systemic and requires correlation echocardiographic laboratory data (usually B-type natriuretic peptide, BNP, or N-terminal pro-B type NT-proBNP). elastography evaluates liver stiffness using transducer that transmits low-frequency vibrations (50 Hz), the speed of shear waves propagating through tissues measured by ultrasound. The faster propagate hepatic...
Introduction Cardiac amyloidosis (CA) is a disease with difficult diagnosis, limited management and reserved prognosis., A high level of suspicion necessary for its identification. There are some clinical clues, such as elderly individuals unexplained left ventricular hypertrophy (LVH), heart failure preserved ejection fraction (HFpEF) restrictive pattern, dissociation between LVH on echocardiography low voltage the electrocardiogram, among others., CA can occur several hemodynamic forms...
Primary Hyperoxaluria type 1 (PH) is a genetic disorder resulting from the hyperproduction of endogenous oxalate, caused by mutations in AGXT gene. The disease results increased serum and urinary levels calcium consequent tissue deposit oxalate crystals, lending to progressive decline renal function, systemic oxalosis involving kidneys, other organs, including heart. present report describes patient with PH1 postmortem analysis.
A elastografia hepática (EH) avalia as consequências sistêmicas da insuficiência cardíaca (IC). Este método pode auxiliar na avaliação prognóstica dos portadores de IC. IC afetar forma secundária a função vários órgãos e sistemas, notadamente o hepático, mediante congestão venosa. O objetivo deste artigo é mostrar, através uma revisão narrativa, importância EH complementar As hepáticas doença cardíaca, por vezes, se mostram silenciosas, sem grandes alterações no exame físico e/ou em exames...
Abstract Introduction Cardiopulmonary exercise testing (CPET) has become an important clinical tool to predict outcome in patients with chronic heart failure (CHF) and help select candidates for transplantation (HTx) or left ventricular assist devices (LVAD). Purpose To evaluate CPET measurements advanced CHF that are being considered HTx LVAD its association early mortality regardless of the performed procedure. Methods Maximum intensity was on a treadmil ramp protocol 65 reduced ejection...
Abstract Background Patients with heart failure (HF) often have altered renal function. Urinary sodium is a marker of diuretic resistance and associated worse prognosis in HF. Growth differentiation factor-15 (GDF-15) oxidative stress inflammation prognostic predictor Objectives We sought to assess the relationship GDF-15 function parameters urinary patients chronic Methods undertook cross-sectional study HF from specialized outpatient clinic. signs symptoms LVEF <50% were included....
The interest in myocardial damage is very old, but only recent decades has there been a reasonable advance greater knowledge thereof. Ancient peoples were limited to rudimentary observations on the morphology and physiology of circulatory system, with special directed heart. Texts cuneiform scripts from Sumer, considered first civilization human history; others Library Ashurbanipal, inscriptions clay tiles, discovered intact under sands at Nineveh; Egyptian hieroglyphs [...]