A5101998467- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- Sex work and related issues
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- HIV, TB, and STIs Epidemiology
- Clostridium difficile and Clostridium perfringens research
- Sepsis Diagnosis and Treatment
- Hepatitis C virus research
- Data-Driven Disease Surveillance
- HIV/AIDS Impact and Responses
- Blood donation and transfusion practices
National Center for AIDS/STD Control and Prevention,China CDC
2015-2019
Center for Disease Control
2014-2017
Chinese Center For Disease Control and Prevention
2017
Institute of Microbiology
2013-2014
Background. Recent studies have indicated an increasing burden of human immunodeficiency virus (HIV)/AIDS among older adults.
Studies have shown a recent upsurge in human immunodeficiency virus (HIV) burden among men who sex with (MSM) China, especially urban areas. For intervention planning and resource allocation, spatial analyses of HIV/AIDS case-clusters were required to identify epidemic foci trends MSM China. Information regarding recorded as cases during 2006–2015 extracted from the National Case Reporting System. Demographic determined through Cochran-Armitage trend tests. Distribution was examined using...
Social disruption associated with coronavirus disease 2019 (COVID-19) threatens to impede access regular healthcare, including for people living HIV (PLHIV), potentially resulting in antiretroviral therapy (ART) interruption (ATI). We aimed explore the characteristics and factors ATI during COVID-19 outbreak China.
Human immunodeficiency virus (HIV) care continuum attrition is a major global public health challenge. Few studies have examined this problem in resource-limited settings. We aimed to assess cumulative, current, and historical achievement along China's HIV of care. A nationwide, serial cross-sectional study all individuals with infection diagnosed China between 1 January 1985 31 December 2015 was conducted using data from HIV/AIDS information systems. Biennial estimates the number persons...
Abstract Dearth of information regarding the trend and correlates HIV, syphilis Hepatitis C (HCV) in a country-wide sample understudied though high-risk Chinese men who have sex with (MSM) called for comprehensive serial cross-sectional study. Using multistage mixed-method strategy, 171,311 MSM from 107 selected cities/counties 30 provinces mainland China, were interviewed tested. Descriptive, bivariate, multivariate Cochran-Armitage analyses conducted using SAS 9.2. During 2009-13, recent...
To find out the diversity of HIV/AIDS epidemic among different areas in China according to their varied characteristics.Seventeen provincial variables, generated from original data and socioeconomic indicators indicate characteristics, were introduced hierarchical clustering analysis form subepidemic areas. Then spatial autocorrelation was applied show distribution cases most-at-risk populations.Three (A, B, C) formed, each which further divided into two clusters, showing China. A1 earliest...
Background Assessing the prevalence of HIV-1 drug-resistance and mutation patterns associated with resistance in geographical regions implementing free antiretroviral therapy (ART) China is necessary for preventing spread resistant strains designing regimens subsequent therapies limited resources. Methods Plasma samples different cities/prefectures were collected at Yunnan Provincial Hospital Infectious Disease from January 2010 to December 2011. Genotyping drug-resistant individuals was...
To estimate the incidence and risk factors for mortality in HIV-1-infected patients China. Information on AIDS-related deaths was collected from Chinese Center Disease Control Prevention's Surveillance Reporting System AIDS Prevention System. A total of 379,348 HIV cases were recorded databases 2006. Among those, 138,288 reported as having developed 72,616 (19%) died after data extracted January 2011. Mortality higher among those aged 50 years old or older (AOR: 3.41, CI: 1.47-7.91) who had...
Abstract To assess the patterns and predictors of AIDS-related mortality identify its correlates among adult people living with HIV/AIDS (PLWHA) in China, a retrospective record-based cohort study was conducted 18 years or older PLWHA, who had at least one follow up reported to national database between January-1989 June-2012. Cumulative Incidence Function used calculate rate. Gray’s test determine variation cumulative incidence across strata. The Fine Gray model measure burden strength...
Objectives This study was designed to identify common HIV-1 mutation complexes affecting the slope of inhibition curve, and propose a new parameter incorporating both IC50 evaluate phenotypic resistance. Methods Utilizing site-directed mutagenesis, we constructed 22 complexes. 10 representative approved drugs novel agent against these mutations were measured determine resistance phenotypes. The values curve calculated, correlations between parameters assessed. Results Depending on class...
China's commitment to implementing established and emerging HIV/AIDS prevention control strategies has led substantial gains in terms of access antiretroviral treatment services, but the evolving multifaceted epidemic China highlights challenges maintaining that response. This study presents modeling results exploring potential impact HIV vaccines Chinese context at varying efficacy coverage rates, while further implications vaccination programs aimed reaching populations highest risk...
Introduction Although AIDS-related deaths have had significant economic and social impact following an increased disease burden internationally, few studies evaluated the cause of among patients with AIDS on combination anti-retroviral therapy (cART) in China. This study examines causes death AIDS-patients China uses a methodology to increase data accuracy compared previous mortality China, that taken reported National HIV Registry at face-value. Methods Death certificates/medical records...
Objective: To explore the HIV epidemic and related factors among MSM in Jilin province. Methods: During implementation of sentinel surveillance program from 2010 to 2015, continuous cross-sectional studies were conducted monitor awareness AIDS, sexual behavior, syphilis positive rates, with sample size no less than 400 each site. Results: From a total 7 823 involved this study. The overall prevalence was 5.4% (42/7 823), an increasing trend during 2015 (Trend test χ(2)=110.023, P<0.001)....