A5035664918- Child and Adolescent Psychosocial and Emotional Development
- Child Abuse and Trauma
- HIV/AIDS Research and Interventions
- Stress Responses and Cortisol
- Maternal Mental Health During Pregnancy and Postpartum
- Child Welfare and Adoption
- Adolescent Sexual and Reproductive Health
- Demographic Trends and Gender Preferences
- Bipolar Disorder and Treatment
- HIV, Drug Use, Sexual Risk
- Global Maternal and Child Health
- Sex work and related issues
- Resilience and Mental Health
- Substance Abuse Treatment and Outcomes
- HIV/AIDS Impact and Responses
- Neuroendocrine regulation and behavior
- Schizophrenia research and treatment
- Birth, Development, and Health
- Posttraumatic Stress Disorder Research
- Prenatal Substance Exposure Effects
- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Epigenetics and DNA Methylation
- Tryptophan and brain disorders
- Child and Adolescent Health
Kennedy Krieger Institute
2015-2023
Johns Hopkins University
2015-2023
Johns Hopkins Medicine
2016-2023
Center for Telepsychology
2020
Ashland (United States)
2019-2020
Yale University
2008-2018
Tsinghua University
2016-2018
Columbia University
1993-2015
VA Connecticut Healthcare System
2015
National Center for PTSD
2006-2014
ObJective: To describe the psychometric properties of Schedule for Affective Disorders and Schizophrenia School-Age Children-Present Lifetime version (K-SADS-PL) interview, which surveys additional disorders not assessed in prior K-SADS, contains improved probes anchor points, includes diagnosis-specific impairment ratings, generates DSM-IfI-R DSM-IV diagnoses, divides symptoms surveyed into a screening interview five diagnostic supplements.Method: Subjects were 55 psychiatric outpatients 11...
In this study, measures of the quality and availability social supports were found to moderate risk for depression associated with a history maltreatment presence short (s) allele serotonin transporter gene promoter polymorphism (5-HTTLPR). The present investigation (i) replicates research in adults showing that 5-HTTLPR variation moderates development after stress, (ii) extends finding children, (iii) demonstrates ability further depression. Maltreated children s/s genotype no positive had...
Child abuse is associated with markedly elevated rates of major depression and other psychiatric disorders in adulthood. This article reviews preclinical studies examining the effects early stress, factors that modify impact these experiences, neurobiological changes depression. Preclinical demonstrate stress can alter development hypothalamic-pituitary-adrenal axis, hypothalamic extrahypothalamic corticotropin releasing hormone, monoaminergic, γ-aminobutyric acid/benzodiazepine systems....
Previous research in adults implicates attention bias posttraumatic stress disorder (PTSD). To study children, the authors used picture-based versions of visual-probe task previously with adults. They tested hypothesis that to threatening facial photographs is associated maltreatment and PTSD.A manipulated threat levels was test 34 children who had been maltreated 21 not maltreated. The involved showing actors faces depicting neutral, angry/threatening, or happy expressions for 500 msec...
<h3>Background</h3> The purported functions of medial temporal lobe structures suggest their involvement in the pathophysiology bipolar disorder (BD). Previous reports abnormalities volume amygdala and hippocampus patients with BD have been inconsistent findings limited to adult samples. Appreciation whether volumetric are early features or represent neurodegenerative changes associated illness duration is by paucity data juvenile <h3>Objective</h3> To investigate hippocampal adults...
This study examined the prevalence of depressive disorders in a sample 56 7- to 12-year-old maltreated children. Overall, 18% met diagnostic criteria for major depression, and 25% dysthymia, with majority children who depression also meeting dysthymia. Ratings different types maltreatment experienced, together measures children's social supports, attributional style, cortisol secretion were determine which most likely evidence disorder. A discriminant analysis conducted using subset these...
The objective of this article was to survey available intimate partner violence (IPV) treatment studies with (a) randomized case assignment, and (b) at least 20 participants per group. Studies were classified into 4 categories according primary focus: perpetrator, victim, couples, or child-witness interventions. results suggest that extant interventions have limited effect on repeat violence, most treatments reporting minimal benefit above arrest alone. There is a lack research evidence for...
Objective This study examined measures of functional impairment and family relations in a sample 62 adolescents with major depressive disorder (MDD) 38 normal controls no history psychiatric illness. Method Ratings the following domains were obtained: mother-child relations, father-child spousal sibling peer school performance. each domain for 3-month period preceding assessment derived from information obtained using semistructured interview administered independently to one their parents....
Etude de l'influence differentes formes mauvais traitement sur le developpement social et emotionnel 70 enfants maltraites compares a 67 d'un groupe controle âges 5 11 ans