A5000085949- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Retinal Diseases and Treatments
- Orthopedic Infections and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Healthcare Systems and Practices
- Pharmaceutical Practices and Patient Outcomes
- Healthcare cost, quality, practices
- Academic integrity and plagiarism
- scientometrics and bibliometrics research
- Infectious Diseases and Tuberculosis
- Pulmonary Hypertension Research and Treatments
- Esophageal and GI Pathology
- Biomedical Ethics and Regulation
- Medication Adherence and Compliance
- Total Knee Arthroplasty Outcomes
- Gastroesophageal reflux and treatments
- Bone health and osteoporosis research
- Clinical Reasoning and Diagnostic Skills
- Mobile Health and mHealth Applications
Hospices Civils de Lyon
2016-2025
Université Claude Bernard Lyon 1
2013-2025
Inserm
2005-2025
Health Services and Performance Research Laboratory
2023-2024
Research on healthcare performance
2023-2024
Université de Lyon
2010-2013
Laboratoire d'Innovation Thérapeutique
2010
Centre Hospitalier Universitaire de Grenoble
2005
Université Grenoble Alpes
2005
Total bilateral corneal limbal epithelial stem cell deficiency (LSCD) cannot be treated with the surgical transplantation of autologous limbus or cultured epithelium. Transplantation allogenic epithelium is possible but requires immunosuppressive treatments. Cultured oral mucosal sheet (CAOMECS) a transparent, resistant, viable, and rapidly bioadhesive sheet, UpCell-Insert technology (CellSeed, Inc., Tokyo, Japan), which allows for grafting onto patient's stroma without suturing. It has...
High-resolution manometry (HRM) might be superior to conventional (CM) diagnose esophageal motility disorders. We aimed compare the diagnosis performed with HRM and CM confirmed at 6 months in a multicenter randomized trial.Patients unexplained dysphagia were undergo either or HRM. Motility disorders diagnosed using Castell Spechler classification for Chicago Diagnosis confirmation was based on clinical outcome response treatment after 6-month follow-up. The initial percentage of diagnoses...
Background and Purpose— Flow diverters are used for endovascular therapy of intracranial aneurysms. We did a nationwide prospective study to investigate the safety effectiveness flow diversion at 12 months. Methods— DIVERSION was national cohort including all placement between October 2012 February 2014 in France. The primary end point event-free survival rate months, defined as occurrence morbidity (intracranial hemorrhage, ischemic stroke, noncerebral or neurological deficit due mass...
Retraction in Medline medical literature experienced a tenfold increase between 1999 and 2009, however retraction remains rare event since it represents 0.02% of publications. Retractions used to be handled following informal practices until they were formalized 2009 by the Committee on Publication Ethics (COPE). The objective our study was describe compliance these guidelines. All retractions published 2008 identified using publication type "retraction publication". notices original...
Conclusions: The database revealed severity factors relating to human papillomavirus (HPV) type and age at diagnosis. While not exhaustive, the is easy use could serve for a European multicentre epidemiological study. Objectives: To propose as starting point national registry estimate prognostic in recurrent respiratory papillomatosis (RRP). Materials methods: This was retrospective study carried out tertiary care teaching hospital. From January 2005 July 2007, epidemiological, clinical...
Heart transplantation (HT) is the gold standard treatment of end-stage heart failure, but organ shortage remains a challenge. This retrospective cohort study assesses economic burden and healthcare pathways patients awaiting HT in French tertiary center. Direct resources were collected valued, state sequence analysis was performed. Ninety-two adult included, with 67 (73%) undergoing within median waiting time 2 months. The mean cost per patient €21,324.05 an average 2.71 hospitalizations....
A portable, single-use incisional Negative Pressure Wound Therapy (iNPWT) device could be used directly on the wound incision following Total Ankle Arthroplasty (TAA). In order to support local decision-making in a French university hospital for adoption of such this indication, three-dimensional (clinical, economic and organizational) Hospital Based-Health Technology Assessment (HB-HTA) was conducted. The HB-HTA based on: literature review; results from PICO-PTC single-site randomized...
To investigate fraud and errors, scientists have studied cohorts of retraction notices. These researches been performed using a PubMed search on publication type "retraction publication" which retrieves the notices retractions. We assessed stability indexation over 15-month period what was time-lag to get stability.A issued in 2008 repeated every 3 months during 15 from February 2011. The first resulted 237 retraction. Throughout study period, 14 discrepancies with initial were observed...
Purpose: To determine predictors of best-corrected visual acuity (BCVA) outcomes 1 year after ranibizumab or bevacizumab treatment for neovascular age-related macular degeneration, within the French Study Group Avastin versus Lucentis degeneration (GEFAL). Methods: Patients aged ≥50 years presenting subfoveal were randomized to receive (3 monthly intravitreal injections followed by an as-needed regimen). The main outcome measures BCVA and its change from baseline at year. Variables with a P...
Abstract Objectives To better understand the process of hospital acquisition innovative medical devices (MDs) and hospital-based health technology assessment (HB-HTA) pathways in France, an in-depth study based on a quantitative approach is needed. The aim present was to assess through national survey how HB-HTA currently implemented French hospitals identify its level formalization. Methods A online conducted among performing with focus MDs for individual use. survey, between March June...
Objective: Chronic prosthetic joint infections (PJI) are serious complications in arthroplasty leading to prosthesis exchange and potential significant costs for health systems, especially if a subsequent new infection occurs. This study assessed the cost of chronic PJI managed with 2-stage at Lyon University Hospital, CRIOAc reference center, France. A threshold analysis was then undertaken determine reimbursement tariff hypothetical preventive device usable time reimplantation, which...