A5012520888- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Polymer Foaming and Composites
- Luminescence Properties of Advanced Materials
- Solid State Laser Technologies
- Chronic Myeloid Leukemia Treatments
- Transport and Logistics Innovations
- Phase Equilibria and Thermodynamics
- Injection Molding Process and Properties
- Polymer crystallization and properties
- Fibroblast Growth Factor Research
- Epigenetics and DNA Methylation
- Laser Design and Applications
- Catalysis and Oxidation Reactions
- Lung Cancer Research Studies
- Cancer, Hypoxia, and Metabolism
- Catalytic Processes in Materials Science
- Ancient and Medieval Archaeology Studies
- Adsorption, diffusion, and thermodynamic properties of materials
- Orthopaedic implants and arthroplasty
- Fungal Plant Pathogen Control
- MRI in cancer diagnosis
- Neuroblastoma Research and Treatments
- Circular RNAs in diseases
- Optical properties and cooling technologies in crystalline materials
Masaryk University
2021-2025
St. Anne's University Hospital Brno
2021-2025
Lund University
2023-2024
University of Žilina
2017-2024
Comtes Fht (Czechia)
2022
Central European Institute of Technology
2018-2019
Central European Institute of Technology – Masaryk University
2018-2019
University of West Bohemia
2012-2016
University of Chemistry and Technology, Prague
2006-2011
Abstract Objectives We prepared 3D poly (ε‐caprolactone) ( PCL ) nanofibre scaffolds and tested their use for seeding, proliferation, differentiation migration of mesenchymal stem cell MSC s). Materials methods nanofibres were using a special collector common electrospinning; simultaneously, 2D layer was classic plain collector. Both seeded with s biologically tested. adhesion, migration, proliferation osteogenic investigated. Results The scaffold characterized by having better biomechanical...
This paper presents research done at the University of Žilina, in cooperation with CEIT (Central European Institute Technology). The topic focus this article is Smart Connected Logistic System, which utilizes all most advanced principles such as Mobile Robotic Systems (MRS), Automated Platforms, Multi-Agent Cloud based control and various IoT concepts. clarifies term Product, exhibited context Logistics.
The scaffold function of the inositol phosphatase SHIP2 mediates sustained ERK signaling downstream FGF receptors.
We report reversal of the FGFR3-related skeletal dysplasia by RNA aptamer designed to neutralize FGFR3 ligand FGF2.
Significance A properly functioning primary cilium is prerequisite for both normal development and aging of all ciliated organisms, including humans. In vertebrates, the signaling Hedgehog family morphogens depends entirely on cilium. Recently, we reported that fibroblast growth factors (FGF) interacts with Hedgehog, this a consequence FGF regulating length speed processes happen therein. report, provide molecular mechanism such interaction, identifying intestinal cell kinase as mediator...
Primary cilium projects from cells to provide a communication platform with neighboring and the surrounding environment. This is ensured by selective entry of membrane receptors signaling molecules, producing fine-tuned effective responses extracellular cues. In this study, we focused on one family fibroblast growth factor (FGFRs), their residence within cilia, its role in FGFR signaling. We show that FGFR1 FGFR2, but not FGFR3 FGFR4, localize primary cilia developing mouse tissues vitro...
Cell communication systems based on polypeptide ligands use transmembrane receptors to transmit signals across the plasma membrane. In their biogenesis, depend endoplasmic reticulum (ER)-Golgi system for folding, maturation, transport and localization cell surface. ER stress, caused by protein overproduction misfolding, is a well-known pathology in neurodegeneration, cancer numerous other diseases. How stress affects via largely unknown. disease models of multiple myeloma, chronic...
Polystyrene (PS) foams are widespread heat insulation and impact absorption materials, but many blowing agents used in their production harmful to the environment. Pentane is a less alternative commonly manufacturing of expandable PS, there inadequate diffusion data pentane PS available literature at conditions relevant impregnation foaming. We conducted gravimetric measurements sorption dynamics n-pentane particles thin films temperatures from 45 110 °C pressures 0 4.8 bar. The measured...
Pigs are frequently used as animal models in experimental medicine. To identify processes of vascular development or regression, elements must be recognised and quantified a three-dimensional (3D) arrangement. Vascular corrosion casts enable the creation 3D replicas trees. The aim our study was to suitable casting media optimise protocol for porcine liver casting.Mercox II® (Ladd Research, Williston, Vermont, USA) Biodur E20® Plus (Biodur Products, Heidelberg, Germany) were tested 4 livers....
The charge transfer luminescence process has been extensively studied due to its influence on the optical properties of various phosphors such as photodarkening which is a limiting factor for lifetime high-power fiber lasers. In this work, we report CT in Yb3+:YAG single crystals at 3.3 eV excitation. It was found that caused by processes between Yb3+ ions and perturbed F+ centers formed during crystal growth incorporation some portion Y3+ into Al3+ sites. systems can be produced low photon...
Neuroblastoma is a childhood developmental cancer; however, its embryonic origins remain poorly understood. Moreover, in-depth studies of early tumor-driving events are limited because the lack appropriate models. Herein, we analyzed RNA sequencing data obtained from human neuroblastoma samples and found that loss expression trunk neural crest–enriched gene MOXD1 associates with advanced disease worse outcome. Further, by using single-cell cells fetal adrenal glands creating in vivo models...
Abstract The research conducted herein builds upon the achievement of a successful and stable 170 × 300 35 mm YAG 5% Yb:YAG single‐crystals production via horizontal directed crystallization method. Based on analysis residual birefringence pattern in analyzed ingots, hypothesis is proposed—debating that certain stages growth, {211} facets start to form within some sections front. sensitivity temperature fluctuations seems cause striations facets’ growth sectors. In later stage process slope...
Abstract The transport of reaction species in polyolefin particles affects both the polymerization and degassing powder down‐stream processing. morphology – that is, distribution polymer pore phases predetermines their behavior. We utilize gravimetric measurements to obtain dynamics determine characteristics porous poly(propylene) particles. found Fick's diffusion model is not generally capable fitting shape curves Therefore we propose a particle including two sizes compact granules...
This paper reconstructs the principle of rubber incorporation in high impact poly(propylene) (hiPP) particles. The detailed information about pores and distribution inside on surface hiPP particles is obtained by micro-computed tomography atomic force microscopy. strong effect homopolymer origin particle morphology demonstrated. To obtain most homogeneous distribution, low porosity required. initial has a negligible thickness layer at medium content. forms not only along iPP primary directly...
Factories of the Future (FoF) gradually advance towards reality. The theoretical concepts leave research laboratories and quickly find their field in industry. This paper introduces Smart Factory issues. authors its first part summarized information from main trends area advanced manufacturing systems. Second shows results own conducted co-operation Mechanical Engineering Faculty University Zilina Spin Off, Central European Institute Technology - CEIT, a.s. chosen implementation innovation...
We used corrosion casts and micro-CT for quantitative description of microvascular network in porcine liver. Using stereological methods, manual tracing microvessels analysis orientation 3D, we quantified the volume fraction, surface density, numerical length density tortuosity series images with 1.875 μm pixel resolution. Biodur E 20 resin was more suitable preparing quantifying tree when compared to Mercox II resin. Quantified data could be applicable correlating 3D models 2D liver...
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