- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Nail Diseases and Treatments
- Food Allergy and Anaphylaxis Research
- Lysosomal Storage Disorders Research
- Contact Dermatitis and Allergies
- Cutaneous lymphoproliferative disorders research
- Eosinophilic Disorders and Syndromes
- Urticaria and Related Conditions
- Asthma and respiratory diseases
- Autoimmune Bullous Skin Diseases
- Fungal Infections and Studies
- Skin Diseases and Diabetes
- Skin and Cellular Biology Research
- Genital Health and Disease
- Glycogen Storage Diseases and Myoclonus
- Carbohydrate Chemistry and Synthesis
- Genetic and rare skin diseases.
- Cancer and Skin Lesions
- Parvovirus B19 Infection Studies
- Herpesvirus Infections and Treatments
- Dermatological diseases and infestations
- Burn Injury Management and Outcomes
- Medicine and Dermatology Studies History
- Syphilis Diagnosis and Treatment
Hochgebirgsklinik Davos
2013-2025
CK-CARE
2010
Technical University of Munich
2000-2009
ENT and Allergy
2005
Max Planck Society
2002
Max Planck Institute of Psychiatry
2002
Amsterdam UMC Location University of Amsterdam
2000
Allergic disorders such as atopic dermatitis (AD) are strongly associated with an impairment of the epithelial barrier, in which tight junctions and/or filaggrin expression can be defective. Skin barrier assessment shows potential to clinically useful for prediction disease development, improved and earlier diagnosis, lesion follow-up, therapy evaluation. This study aimed establish a method directly assess vivo status using electrical impedance spectroscopy (EIS).Thirty-six patients AD were...
Background The role of atopy in the pathophysiology eczema is still under debate. concept and analyses nonatopic atopic subtypes have gained increasing interest recent studies. course these differences between boys girls not been investigated so far. Objectives To examine preschool children from Germany with regard to sex. Methods Repeated cross-sectional studies were performed 5–7-year-old 1994 2000. Individuals identified by a dermatological examination. In addition questionnaire, skin...
In both clinical experience and molecular genetic studies, atopic diseases (asthma, rhinoconjunctivitis eczema) have been found to be strongly genetically influenced. The epidermal protein filaggrin seems play a crucial role is encoded within the so-called differentiation complex on chromosome 1. Filaggrin mutations predispose significantly an increased risk develop eczema. Apart from filaggrin, other proteins involved in skin barrier functions such as lipid synthesis metabolism, protease or...
The role of immunization in the development atopic disorders is still under debate. One reason might be, that because high vaccination coverage most countries only few and selected children are not immunized, leading to unstable often biased effect estimates. In Germany, situation was different between 1985 1991: bacillus Calmette‐Guérin (BCG) pertussis were officially recommended numbers non‐vaccinated 1990s. We report on a cross‐sectional study with 1673 participants among 5‐ 7‐year‐old...
Abstract Background Pimecrolimus cream 1% has been shown to effectively control atopic eczema (AE) when applied twice daily from the first signs or symptoms of AE until clearance. Moreover, pimecrolimus a favourable safety profile, lacking topical corticosteroid‐related side‐effects such as skin atrophy, making it particularly useful treat delicate body regions (e.g. face). Objective The objective this naturalistic study was monitor safety, tolerability and efficacy used in long‐term...
Two patients encountered a first-degree cold burn after use of deodorant spray. The spray-nozzle to skin-surface distance was approximately 5 cm, and the spraying lasted 15 seconds. Under laboratory conditions, in able induce decline temperature >60 degrees C. These 2 cases highlight little-known potential for skin damage by sprays if used improperly.