A5100604194- Thyroid Cancer Diagnosis and Treatment
- Signaling Pathways in Disease
- Cancer-related molecular mechanisms research
- Nanoplatforms for cancer theranostics
- Electrospun Nanofibers in Biomedical Applications
- Synthesis and Biological Activity
- Bone Tissue Engineering Materials
- Marine Sponges and Natural Products
- Nanoparticle-Based Drug Delivery
- Renal and related cancers
- Advanced Nanomaterials in Catalysis
- RNA Research and Splicing
- Neuropeptides and Animal Physiology
- DNA and Nucleic Acid Chemistry
- Neuroendocrine Tumor Research Advances
- Microbial Natural Products and Biosynthesis
- Cancer, Stress, Anesthesia, and Immune Response
- Hops Chemistry and Applications
- Cancer-related Molecular Pathways
- Natural Compound Pharmacology Studies
- Caveolin-1 and cellular processes
- Ferroptosis and cancer prognosis
- Graphene and Nanomaterials Applications
- FOXO transcription factor regulation
- Head and Neck Anomalies
Liaoning Cancer Hospital & Institute
2025
Dalian University of Technology
2025
University of South China
2024
Anhui Medical University
2023
South China University of Technology
2022
First Affiliated Hospital of GuangXi Medical University
2017-2020
Guangxi Medical University
2017-2020
Shanghai Institutes for Biological Sciences
2015
Center for Excellence in Molecular Cell Science
2015
First Affiliated Hospital of Zhengzhou University
2011
The majority of chitosan-based bone tissue engineering (BTE) scaffolds have the problem poor mechanical properties. However, modifying chitosan with conventional silane coupling agents to improve properties will introduce additional complications, including cytotoxicity and biocompatibility. In this study, two types organic–inorganic composite (F-A-T0/T3/T5 F-B-T5-P0/P0.5/P1.5/P2.5) were prepared using nanofibers (CSNF) by beating-homogenization method, combined sol–gel further introduced...
The role of long non-coding RNA (lncRNA) HOX transcript antisense (HOTAIR) in thyroid carcinoma (TC) remains unclear. current study was aimed to assess the clinical value HOTAIR expression levels TC based on publically available data and evaluate its potential signaling pathways. information concerning were downloaded from Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO), respectively. Furthermore, 3 online biological databases, Starbase, Cbioportal, Multi Experiment Matrix, used...
Abstract G-quadruplex (G4) DNA and G4 resolvase are involved in a variety of biological processes. To understand the function structures their resolvases spermatogenesis, we investigated distribution mouse testis identified alterations during spermatogenesis. Meanwhile, studied RNA helicase associated with AU-rich element (RHAU), resolvase, spermatogenesis germ-cell-specific knockout model. The results showed that ablation RHAU germ cells caused increase thus resulted decrease spermatogonial...
Scholars are striving to apply molecular biology involving long non-coding RNA (lncRNA) in the prognostication of papillary thyroid cancer (PTC). However, clinical role lncRNAs prognostic setting PTC is still unclear. Herein, a comprehensive inquiry was performed screen lncRNA expression profiling with 507 patients from The Cancer Genome Atlas RNA-sequencing datasets. A total 734 were detected be aberrantly expressed, among which three novel including AC079630.2, CRNDE and CTD-2171N6.1...
A new 1,4-diazepine, callysponine (1), was isolated from a South China Sea Callyspongia sp. marine sponge, together with four known proline-based diketopiperazines: cyclo-(S-Pro-R-Leu) (2), cyclo-(S-Pro-R-Val) (3), cyclo-(S-Pro-R-Ala) (4), andcyclo-(S-Pro-R-Tyr) (5). The structure determined on the basis of NMR and MS analysis, absolute stereochemistry defined by NOESY spectroscopy optical rotation. structures compounds were identified comparison their spectroscopic data those reported in...
Chemodynamic therapy, which relies on the generation of cytotoxic radicals, can be amplified by a nanoplatform that produces hydroxyl radicals while also compromising natural radical scavenging mechanisms. For this purpose, well-defined amphiphilic terpolymer, poly(oligo(ethylene glycol) monomethyl ether methacrylate)-block-poly(N,N-dimethyl aminoethyl methacrylate-statistical-monomer bearing ferrocene graft via azobenzene linker) (POEGMA-b-P(DMAEMA-st-(M-Azo-Fc), denoted as PAzo-Fc) is...
Abstract Background Thyroid cancer (TC) is the most common endocrine malignancy; basigin (also known as BSG) plays a crucial role in tumor cell invasion, metastasis, and angiogenesis. This study was designed to identify change of BSG expression TC its possible potential mechanism. Methods The levels were demonstrated using data collected from in-house immunohistochemical (IHC), RNA-sequencing (RNA-seq), microarrays, literatures. Integrated analysis performed determined comprehensively. Gene...
Abstract Background Thyroid cancer (TC) is the most common endocrine malignancy, Basigin (also known as BSG) plays a crucial role in tumor cell invasion, metastasis, and angiogenesis. This study was designed to identify change of BSG expression TC its possible potential mechanism. Methods The levels were demonstrated using data collected from in-house immunohistochemical (IHC), RNA-sequencing (RNA-seq), microarrays literatures. Integrated analysis performed determined comprehensively. gene...
Objective To investigate the relationship of vascular endothelial growth factor-C and microvessel lymphatic vessel development nephroblastoma. MethodsThe expression was detected by immunohistochemistry (PV9000) method in nephroblastoma (46 cases), tissue adjacent to tumor (19 eases) normal kidney (8 cases). The density (MVD) (LVD) were assessed after with CD34 LYVE-1. correlation between expressions VEGF-C, MVD, LVD clinicopathological parameters analyzed univariate method. overall survival...
Objective This study aim to assess the expressions of high mobility group box chromosomal proteinl ( HMGB1) and receptor foradvanced glycation end products (RAGE) vascular endothelial growth factor (VEGF) in Wilms'tumor their clinical significance both tumor blood vessel infiltrates lymph node metastasis. Methods Fifty cases samples, which had been confirmed by pathology, were collected from The First Affiliated Hospitals Zhengzhou University january 2003 2010. And 15 taken adjacent kidney...
Chronic inflammation leads to cellular damage, which is considered responsible for the development of many diseases including cancer. Natural compounds extracted from traditional Chinese herbal medicines have been developed and utilized treatment chronic inflammation. Hypericum beanii, a folk medicine plant, has used treat variety inflammation-related showed promising potential as an antitumor herb. However, there no studies on H. beanii view cancer-related inflammation strategies. In this...
Abstract Background: Thyroid cancer (TC) is the most common endocrine malignancy, Basigin (also known as BSG) plays a crucial role in tumor cell invasion, metastasis, and angiogenesis. This study was designed to identify change of BSG expression TC its possible potential mechanism. Methods: The levels were demonstrated using data collected from in-house immunohistochemical (IHC), RNA-sequencing (RNA-seq), microarrays literatures. Integrated analysis performed determined comprehensively. gene...