- Statistical Methods and Bayesian Inference
- Composite Structure Analysis and Optimization
- Advanced Statistical Methods and Models
- Energetic Materials and Combustion
- High-Velocity Impact and Material Behavior
- Statistical Methods and Inference
- Rocket and propulsion systems research
- Statistical Distribution Estimation and Applications
- Vibration and Dynamic Analysis
- Anesthesia and Pain Management
- Structural Load-Bearing Analysis
- Acoustic Wave Phenomena Research
- Cardiac Ischemia and Reperfusion
- Fusion materials and technologies
- Fluid Dynamics Simulations and Interactions
- Cardiac, Anesthesia and Surgical Outcomes
- Statistical Methods in Clinical Trials
- Spacecraft and Cryogenic Technologies
- Pain Mechanisms and Treatments
- Magnetic confinement fusion research
- Bayesian Methods and Mixture Models
- Ion channel regulation and function
- Nausea and vomiting management
- Neuroscience and Neuropharmacology Research
- Metallurgy and Material Forming
PLA Rocket Force University of Engineering
2019-2025
Huazhong University of Science and Technology
2014-2025
Tongji Hospital
2012-2025
Shanxi Academy of Medical Sciences
2023-2025
Northwestern Polytechnical University
2024-2025
Naval Research Academy
2019-2024
Zhejiang Ocean University
2022-2024
Xi'an High Tech University
2012-2023
Harbin Engineering University
2018-2022
PLA Navy General Hospital
2014-2022
Food and other environmental factors affect gene expression behaviour of animals. Differences in bacterial food the longevity Caenorhabditis elegans. However, no research has been carried out to investigate whether bacteria could utilize endogenous RNAs C. elegans physiology. Here we show that two Escherichia coli noncoding RNAs, OxyS DsrA, impact on physiology downregulates che-2, leading impairment chemosensory DsrA suppresses diacylglycerol lipase F42G9.6, a decrease longevity. We also...
Exon–intron circRNAs (EIciRNAs) are a circRNA subclass with retained introns. Global features of EIciRNAs remain largely unexplored, mainly owing to the lack bioinformatic tools. The regulation intron retention (IR) in and associated functionality also require further investigation. We developed framework, FEICP, which efficiently detected from high-throughput sequencing (HTS) data. distinct exonic (EcircRNAs) aspects such as larger length, localization nucleus, high tissue specificity,...
N-methyl-D-aspartate (NMDA) receptors in sensory afferents participate chronic pain by mediating peripheral and central sensitization. We studied the presence of NMDA receptor subunits different types primary afferents. Western blots indicated that rat dorsal root ganglia (DRG) contain NR1, NR2B, NR2C, NR2D but not NR2A. Real-time RT-PCR showed NR2B were expressed at higher levels than NR2A NR2C DRG. Immunofluorescence with an antibody recognized NR1 another colocalized 90% DRG neurons,...
This study aims to investigate the in-situ microscopic damage evolution mechanism of hydroxyl-terminated polybutadiene (HTPB) propellant bonding interface under multi-angle tensile shear conditions as well characterize effects on macroscopic failure modes. To this end, micro-specimens HTPB with different loading angles are scanned and reconstructed using micro-computed tomography (CT), data sizes, shapes, volume fractions particles inclusions inside obtained. The results indicate existence a...
In order to study the macroscopic mechanical properties and meso damage mechanism of solid fuel hydroxy-terminated polybutadiene (HTPB) propellant under low temperature dynamic biaxial compression loading, INSTRON high strain rate hydraulic testing machine was used carry out test HTPB in range −50 °C ∼ -30 1s−1–85s−1. Meanwhile, control at room (25 °C) set up, microcomputed tomography (Micro-CT) observe quantitatively characterize loaded specimens. The results show that significantly affect...
G protein-coupled inward rectifier K(+) (GIRK) channels regulate cellular excitability and neurotransmission. The GIRK are activated by a number of inhibitory neurotransmitters through the protein betagamma subunit (G(betagamma)) after activation receptors inhibited several excitatory phospholipase C. If inhibition is produced PKC, there should be PKC phosphorylation sites in channel proteins. To identify sites, we performed systematic mutagenesis analysis on GIRK4 GIRK1 subunits expressed...
This paper introduces a conceptual framework for finite element analysis of generalized Maxwell viscoelastic materials based on the initial stress approach. The proposed method facilitates explicit and convenient determination mechanical parameters by directly utilizing relaxation test data. Each time step’s is treated as stress, recursive calculation formula material’s established, relying solely strain from previous step. Based this, study outlines computational steps initial-stress-based...
Asian countries adjacent to the Golden Triangle and their neighbors have witnessed an evolution in "drug abuse" from traditional opium smoking heroin eating, smoking, finally injection. A recent study of 630 users was conducted China's Yunnan Province, located close Triangle. Data collected between August 1997 February 1998 indicate injecting users, comparison noninjectors, were more likely used drugs for a longer period time, use frequently everyday. Other major differences existed urban...
Abstract Dewetting is the main damage mode of composite solid propellants, and research on initiation mechanism evolution process dewetting an important way to predict mechanical properties evaluate life propellants. In this paper, experimental analytical methods dewettingare reviewed at domestic foreign from three dimensions: macro, meso micro. On basis, reference solutions existing problems are proposed, key directions interface in future pointed out. The analysis shows that behavior...