A5011733673- Natural product bioactivities and synthesis
- Genetic Mapping and Diversity in Plants and Animals
- Inflammatory Bowel Disease
- Rice Cultivation and Yield Improvement
- Liver Disease Diagnosis and Treatment
- Nanocomposite Films for Food Packaging
- Plant Disease Resistance and Genetics
- Phytochemicals and Antioxidant Activities
- Nanoparticles: synthesis and applications
- Cell Adhesion Molecules Research
- Natural Compounds in Disease Treatment
- Phytochemical compounds biological activities
- Sirtuins and Resveratrol in Medicine
- Inflammasome and immune disorders
- Conducting polymers and applications
- Pineapple and bromelain studies
- Pharmacological Effects of Natural Compounds
- Signaling Pathways in Disease
- Genetics and Plant Breeding
- Synthesis and biological activity
- Psoriasis: Treatment and Pathogenesis
- Diet, Metabolism, and Disease
- Retinoids in leukemia and cellular processes
- Tannin, Tannase and Anticancer Activities
- Toxin Mechanisms and Immunotoxins
Central South University of Forestry and Technology
2021-2025
Central South University
2021-2024
Northwestern University
2008
Huazhong Agricultural University
1998
Virginia Tech
1996-1997
Inflammatory bowel disease (IBD) is a global chronic with long duration and repeated relapse. Currently, there still lack of effective approaches to prevent IBD. Food-derived oryzanol (ORY) possesses extensive biological activities, such as ameliorating diseases, antioxidation, antiobesity. However, the mechanism ORY in preventing colitis remains unclear. The present research aims explore potential dextran sulfate sodium (DSS)-stimulated rat model. results showed that symptoms were...
Excessive oxidation can lead to inflammation and affect health. Studies have shown that ursolic acid (UA) gallic are widely employed in medicine cosmetics owing their obvious antioxidant anti-inflammatory properties. In this study, a series of 16 novel UA hybrids tethered via 1,2,3-triazole the modified gallate moieties were synthesized CuAAC 1,3-cycloaddition reactions. vitro, all derivatives proved be effective antioxidation anti-inflammation activities. Interestingly, compound 20...
High-fat diet (HFD) is closely related to the formation of metabolic diseases. Studies have confirmed that neohesperidin dihydrochalcone (NHDC) possesses biological activity preventing glycolipid metabolism disorder. To explore mechanism its preventive against glucolipid disorder, HFD-treated rats were orally administered with NHDC for 12 weeks continuously. The results showed that, compared HFD group, intervention 40-80 mg/kg body weight effectively downregulated level fasting blood...
Extensive research has been conducted on Camellia oleifera Abel., a cultivar predominantly distributed in China, to investigate its phytochemical composition, owning potential as an edible oil crop. Pentacyclic triterpene saponins, essential active constituents, play significant role contributing the pharmacological effects of this cultivar. The saponins derived from C. (CoS) offer diverse array bioactivity benefits, including antineoplastic/bactericidal/inflammatory properties,...
Theasaponin derivatives, which are reported to exert antitumor activity, have been widely exist in edible plants, including the seed cake of Camellia oleifera (C.), is extensively grown south China. The purpose this study was isolate new theasaponin derivatives from C. and explore their potential activity underlying molecular mechanism. In present study, we first isolated identified four (compounds 1, 2, 3, 4) total aglycone extract by utilizing a combination pre-acid-hydrolysis treatment...
Studies have revealed that a novel anti-inflammatory mediator─maresin-1 (MaR1)─can reduce the level of inflammatory factors. There is evidence physical exercise (PE) promotes biosynthesis MaR1, leading to prevention rheumatoid arthritis (RA). Previously, we proven resveratrol can mitigate formation RA. Pterostilbene (Pte) an analogue resveratrol, but it around four times more bioavailable. Hence, hypothesize Pte could be effective in preventing RA, particular, when accompanied by moderate...
is a predominant anthracnose species in
Previous research has consistently shown that high-fat diet (HFD) consumption can lead to the development of colonic inflammation. Neohesperidin (NHP), a naturally occurring flavanone glycoside in citrus fruits, anti-inflammatory properties. However, efficacy and mechanism NHP countering prolonged HFD-induced inflammation remains unclear. In this study, rats on HFD were intragastric administered (i.g.) with for 12 consecutive weeks. Results indicated natural compound is effective reducing...
Tangeretin (Tan) possesses great anti-oxidation and anti-inflammation bioactivities; however, it is accompanied by poor water solubility, which leads to inefficient cellular internalization. To address this issue, a reactive oxygen species (ROS)-triggered poly (thioether-polyesters) micelle (PDHP, PEG-DTT) was designed prepared via self-assembly, consisted of as the hydrophilic shell, drug Tan hydrophobic inner core. The micelles (Tan@ PDHP), with 63.15% loading efficiency Tan, showed...
Purpose of the StudyTo investigate effect inositol on inhibiting AKT-driven beta-catenin signaling and aberrant activation intestinal stem cells long-lived progenitors in DSS-induced colitis colitis-induced carcinogenesis mice.