A5040412165- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- HIV-related health complications and treatments
- HIV/AIDS Impact and Responses
- Child Nutrition and Water Access
- Congenital Anomalies and Fetal Surgery
- Pneumocystis jirovecii pneumonia detection and treatment
- Congenital Diaphragmatic Hernia Studies
- Ocular Disorders and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Cleft Lip and Palate Research
- Prenatal Screening and Diagnostics
- Craniofacial Disorders and Treatments
- Malaria Research and Control
- Cytomegalovirus and herpesvirus research
- Urological Disorders and Treatments
- Pericarditis and Cardiac Tamponade
- Infant Nutrition and Health
- Parasites and Host Interactions
- Diagnosis and treatment of tuberculosis
- Foreign Body Medical Cases
- Esophageal and GI Pathology
Centre International De Reference Chantal Biya
2016-2025
University Teaching Hospital of Yaounde
2012-2024
Université de Yaoundé I
2015-2024
Financial Management Association International
2014
Yaoundé Gynaecology, Obstetrics and Pediatrics Hospital
2006
This study aimed to compare viral suppression (VS) between children, adolescents, and adults in the frame of transition dolutegravir (DTG)-based antiretroviral therapy (ART) Cameroonian context. A comparative cross-sectional was conducted from January 2021 through May 2022 amongst ART-experienced patients received at Chantal BIYA International Reference Centre Yaounde-Cameroon, for load (VL) monitoring. VS defined as VL < 1000 copies/mL undetectability 50 copies/mL. Chi-square multivariate...
Achieving and maintaining viral suppression (VS) in pediatric populations remain suboptimal low- middle-income countries (LMICs), calling for the optimized management approaches. We compared rate of confirmed virological failure (cVF) associated factors among virally non-suppressed (VnS) children adolescents after enhanced adherence counseling (EAC) on dolutegravir-based versus other regimens. A multicentre prospective cohort study was conducted ART-experienced (<10 years) (10-19 with VnS...
About 90% of new HIV-1 infections in children occur sub-Saharan Africa, where treatment monitoring remains suboptimal. We sought to ascertain factors associated with immunovirological responses among an ART-experienced paediatric population Cameroon. A laboratory-based and analytical study was conducted from January 2017 throughout December 2020 wherein plasma viral load (PVL) analyses CD4 cell counts were performed. Viral suppression (VS) defined as PVL < 1000 copies/mL immunological...
High mother-to-child (MTC) transmission rate of HIV might contribute to the increased pandemic rate. The aim this study was identify knowledge, attitude and practices health personnel working in maternities prevention MTC HIV. This cross-sectional descriptive carried out from 20th February 30th April, 2017. All maternity wards were included study. variables recorded their age, grade, experience (number year practice), gender, educational level, structure training Analyses done using SPSS...
Introduction: la mise en œuvre des directives de l'OMS permettrait réduire significativement mortalité hospitalière due à malnutrition sévère. Cependant, elle n'est pas effective et pénurie aliments thérapeutiques est l'une principales causes. L'étude décrit notre expérience sur prise charge aigue sévère avec laits alternatifs aux F75 F100 composés localement.
Introduction: this study aimed at assessing the prevalence of Human Immunodeficiency Virus (HIV) among health care workers (HCWs) and to evaluate some risks factors for HCWs.
Sub-Saharan Africa (SSA) alone has nine out of every 10 children living with HIV globally and monitoring in this setting remains suboptimal, even as these grow older. With scalability antiretroviral therapy (ART), several HIV-infected are growing towards adolescence (over 2.1 million), the potentials to reach adulthood. However, despite an overall reduction HIV-related mortality, there increasing deaths among adolescents (ADLHIV), limited evidence for improved policy-making. Of note,...
Intestinal parasitic infections are among the most common communicable diseases worldwide, particularly in developing countries. Human immunodeficiency virus (HIV) causes dysregulation of immune system through depletion CD4+ T lymphocytes which gives rise to opportunistic infections.A cross-sectional study was conducted from January October 2018. Stool and blood samples were collected participants aged 1 19. analyzed for intestinal parasites. Blood HIV CD4 + cell counts.Out 214 children...
Abstract Background Sub-Saharan African countries are transitioning to dolutegravir-based regimens, even for patients with extensive previous drug exposure, including first-generation integrase strand-transfer inhibitors (INSTI) such as raltegravir. Such exposure might have implications on cross-resistance antiretroviral therapies (ART). Case presentation We report a 65 years old Cameroonian, previously exposed raltegravir, and failing third-line treatment multi-drug resistance darunavir/r...
Abstract Background The high rate of mortality among HIV-vertically infected adolescents might be favoured by HIV drug resistance (HIVDR) emergence, which calls for timeous actions in this underserved population. We thus sought to evaluate program quality indicators (PQIs) HIVDR on antiretroviral therapy (ART). Methods A study was conducted the Centre region Cameroon (10–19 years) receiving ART two urban (The Mother–Child Chantal BIYA Foundation, National Social Welfare Hospital) and three...
Abstract Background Visible congenital malformations (VCMs) are one of the principal causes disability in world. Prenatal diagnosis is a paramount mandatory integral part follow up pregnancies with VCM foetus high-income setting. We aimed to determine incidence prenatal VCMs low-resource setting no policy on antenatal VCMs. Methods carried out prospective cohort multicenter study from July 2015 June 2016 10 randomly selected maternity units Yaoundé, Cameroon. enrolled all newborns or more...
Objective: The aim of this study was to assess the effectiveness nevirapine (NVP) in prevention mother-to-child transmission (MTVT) HIV-1 children Yaounde University Teaching Hospital, Cameroon. Methods: This a prospective and descriptive hospital-based which pre-counselled HIV-infected pregnant women who gave their consent were included. At onset labour single dose 200 mg oral NVP administered each woman. Their newborns also given 2 mg/kg syrup within 72 hours birth. These NVP-treated...
To analyse the outcome of children with empyema thoracis treated by decortication followed a simple drainage system.Retrospective chart review from July 2001 to June 2010 all cases who had thoracotomy for empyema. We used an endotracheal tube as chest drain and urinary bag collector. Statistical analyses were done using EXCEL SPSS 9.0.Forty one underwent empyema, there 23 boys 18 girls sex ratio 1, 21. The mean age was 2½ years minimum 1 month maximum 15 age; 27 below two age. All patients...
Objectiv: To analyze the determinants of decision to incision interval in case emergency caesarean section Yaoundé’ hospitals
 Methods: A prospective cross-sectional (affected / non-affected) study was conducted four hospitals Yaoundé between January and may 2017 after National Ethical Committee approval. The target population women who benefited from during period. Crude Odds Ratio (OR) adjusted odds ratio (AOR) with 95% Confidence Interval used appreciate association several...
Introduction: l'objectif de ce travail était d'évaluer l'impact du traitement antirétroviral sur le profil biologique des enfants VIH positifs suivis au Centre Hospitalier et Universitaire Yaoundé Cameroun.
Massive purulent andacute pericarditis in children is a life-threatening disease associated with high mortality. It has been described tocomplicate usuallya bronchopulmonary infectionbut currently uncommon the era of antibiotics. Acute and massive rarely reported association human immunodeficiency virus (HIV) infection. This case a10-year-old boy who presented signs sepsis cardiac tamponade due to staphylococcal complicating an unknown HIV infection.The child underwent pericardiectomy,...
Data were obtained from 290 HIV-positive children aged 5–18 years in Burundi, Cameroon, and the Democratic Republic of Congo. We compared characteristics those who knew their HIV serostatus (disclosed) with that did not (undisclosed) using chi-square tests at enrollment 6-month follow-up. used logistic regression to determine if disclosure status was associated antiretroviral therapy (ART) adherence. Of 144 disclosed children, median age 10 years. Disclosed undisclosed similar demographic...
Background: In Cameroon, the prevalence of HIV in pregnant women was 7.8% 2012, and they were 8500 positive newborns 2013. Option B+ is first highly active antiretroviral therapy (HAART) preventive protocol. The objective to evaluate rate transmission on children born from mothers who during pregnancy, three university teaching hospitals University Yaoundé I. Methods: It a retrospective, cross-sectional study over period four years (2013-2017). We included not previous treatment received...
Malaria is still the primary cause of pediatric deaths. The efficient management malaria requires its rapid and accurate diagnosis. To fulfill this requirement, diagnostic tests have been developed, but their evaluation before commercialization never exhaustive. aim study was to evaluate performance a test (SD Bioline Antigen P.f/Pan) diagnose in children.Testing conducted on children aged between 6 months 15 years who were examined at "Centre Mère Enfant (CME) "Chantal Biya" Foundation...
HIV infection is characterized by changes in the composition and functions of gut microbiota. We carried out a study aiming at comparing compositional digestive flora infected infants versus that non Cameroon.A case-control was during which stool sample collected from each participant after obtaining proxy consent. Stools were cultured using aerobic, strict anaerobic, 10% CO2 micro-aerophilic conditions specific culture media bacteria identified biochemically. Fisher's exact test used for...
Introduction: Access to antiretroviral drugs has improved the survival of children infected with Human Immunodeficiency Virus (HIV). As they reach adolescence, are confronted various constraints related infection and its treatment, in addition those growth period going through. The main aim study was assess acceptance describe experience HIV by adolescents but also investigate factors associated good a positive experience. Methodology: cross-sectional analytic concerned HIV-infected aged 15...
Background: HIV case finding is an essential component for ending AIDS, but there limited evidence on the effectiveness of such a strategy in pediatric population. We sought to determine positivity rates among children according entry points Cameroon. Methods: A facility-based survey was conducted from January 2015 December 2019 mother–child couples at various health facilities six regions questionnaire administered parents/guardians. Children were tested by polymerase chain reaction (PCR)....