A5017461477- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Sex work and related issues
- HIV/AIDS Impact and Responses
- Adolescent Sexual and Reproductive Health
- Mosquito-borne diseases and control
- Pneumocystis jirovecii pneumonia detection and treatment
- Malaria Research and Control
- LGBTQ Health, Identity, and Policy
- Cervical Cancer and HPV Research
- Congenital Anomalies and Fetal Surgery
- Global Maternal and Child Health
- Reproductive tract infections research
- HIV-related health complications and treatments
- Prenatal Screening and Diagnostics
- Healthcare Systems and Practices
- Parasites and Host Interactions
- Pregnancy and Medication Impact
- Parasite Biology and Host Interactions
- SARS-CoV-2 detection and testing
- Venomous Animal Envenomation and Studies
- Blood donation and transfusion practices
- Immune responses and vaccinations
Université de Yaoundé I
2016-2025
Ministry of Public Health
2012-2025
Central Hospital of Yaoundé
2022-2023
National Radiation Protection Agency of Cameroon
2012-2023
Elizabeth Glaser Pediatric AIDS Foundation
2022
University of Douala
2022
National AIDS Council
2022
Comité National de Lutte contre le SIDA
2013-2020
University of Buea
2020
Female sex workers (FSWs) are at risk for HIV and physical sexual gender-based violence (GBV). We describe the prevalence of lifetime GBV its associations with behaviour, access to health services barriers in accessing justice among FSWs Cameroon.FSWs (n=1817) were recruited a cross-sectional study through snowball sampling seven cities Cameroon. examined key outcomes via adjusted logistic regression models.Overall, 60% (1098/1817) had experienced or their lifetime. was associated...
Introduction Despite men who have sex with (MSM) being a key population for HIV programming globally, epidemiologic data on MSM in Central Africa are sparse. We measured and syphilis prevalence the factors associated infection among Cameroon. Methods Two hundred seventy‐two 239 aged ≥18 from Douala Yaoundé, respectively, were recruited using respondent‐driven sampling (RDS) this cross‐sectional surveillance study 2011. Participants completed structured questionnaire testing. Statistical...
Abstract Background After the launching of « Test & Treat » strategy and wider accessibility to viral load (VL), evaluating virological success (VS) would help in meeting UNAIDS targets by 2020 Cameroon. Setting methods Cross-sectional study conducted Chantal BIYA International Reference Centre for research on HIV/AIDS prevention management (CIRCB), Yaoundé, Cameroon; data generated between October 2016 August 2017 amongst adults, adolescents children at 12, 24, 36 ≥ 48 months ART. VS...
This study aimed to compare viral suppression (VS) between children, adolescents, and adults in the frame of transition dolutegravir (DTG)-based antiretroviral therapy (ART) Cameroonian context. A comparative cross-sectional was conducted from January 2021 through May 2022 amongst ART-experienced patients received at Chantal BIYA International Reference Centre Yaounde-Cameroon, for load (VL) monitoring. VS defined as VL < 1000 copies/mL undetectability 50 copies/mL. Chi-square multivariate...
In general populations, consistent data highlight the relationships among violence, HIV risk behavior and depression; however, these patterns are not well understood female sex workers (FSWs). We examined relationship between FSWs' experiences with sexual violence condom use as a key explored mental health potential mediator.In total, 2,165 FSWs were recruited via respondent-driven sampling in Cameroon 2016. The women answered questions about health.Inconsistent clients was reported by 23.5%...
Men who have sex with men (MSM) and female workers (FSW) are more likely to be living HIV experience difficulty accessing health services due stigma discrimination. Antiretroviral treatment sustained viral suppression among individuals is the last step in continuum of care, which has been shown improve outcomes decrease risk onward transmission HIV.To calculate numerator denominator for antiretroviral therapy (ART) coverage estimates MSM FSW HIV, Priority Locations AIDS Control Efforts...
Female sex workers (FSWs) in Cameroon, and West Africa generally, suffer a disproportionate burden of HIV. Although violence against FSWs has been documented extensively other parts the world, data on from African countries are lacking. The aim this study was to qualitatively document harm reduction strategies perspective Cameroon as well understand how experiences may increase FSWs' HIV risk.FSWs 7 major cities (Douala, Yaounde, Bamenda, Bertoua, Nagoundere, Kribi, Bafoussam) were...
Background The majority (>95%) of new HIV infection occurs in resource-limited settings, and Cameroon is still experiencing a generalized epidemic with ~122,638 patients receiving antiretroviral therapy (ART). A detrimental outcome scaling-up ART the emergence drug resistance (HIVDR), suggesting need for pragmatic approaches sustaining successful performance. Methods survey was conducted 15 sites Centre Littoral regions 2013 (10 urban versus 05 rural settings; 8 at tertiary/secondary 7...
Background Men who have sex with men (MSM) are more likely to be living HIV than other adult in low- and middle-income countries. MSM experience barriers accessing services including a lack of available specialized care, community-level stigma discrimination. This study aims examine the uptake at non-governmental community-based organizations (NGOs/CBOs) identify ways improve coverage prevention treatment among MSM. Methods An Integrated Biological Behavioral Surveillance (IBBS) survey was...
Limited studies have reported the outcomes of lifelong antiretroviral therapy (ART) amongst adolescents living with HIV (ALWHIV) in resource-limited settings (RLS), thus classifying this population as underserved. We therefore aimed to ascertain immunological and virological responses, associated factors Cameroonian ALWHIV.A cross-sectional observational study was conducted from January through May 2016 at National Social Insurance Fund Health Centre Yaoundé-Cameroon. Immunological responses...
Introduction HIV prevalence disproportionately affects high-risk populations, particularly female sex workers in Africa. Women and girls engaging transactional (WGTS) face similar health risks from unsafe practices, economic vulnerabilities stigma. However, they are not recognised. Methods Using existing literature data the POWER randomised controlled trial, we developed a deterministic compartmental model to assess dynamics among WGTS, their sugar daddies low-risk populations. We evaluated...
Significant progress has been made in onchocerciasis control through mass distribution of ivermectin among affected human populations, fostering optimism for disease elimination. However, despite these considerable advances, the elimination remains a major challenge many African foci. This paper describes current situation Adamaoua Region Cameroon after 20 consecutive years treatment. The study was conducted between August and September 2020 Cameroon. Onchocerciasis endemicity assessed...
For the 30 million people living with HIV on antiretroviral therapy, routine viral load testing is recommended to monitor treatment effectiveness. However, only an estimated 77% of eligible accessed in 2022, due barriers including high costs tests. Here we assessed implementation pooled increase efficiency at a reference laboratory Cameroon. Plasma specimens were tested pools three using Abbott RealTime HIV-1 Viral Load assay. detected, each specimen was then and reported individually; for...
Background: HIV infection persists at very high levels compared to other parts of the world. It devastates youth and thus jeopardizes development countries. This indicates that success numerous interventions aimed changing sexual behaviors adolescents young people could be questioned. These often focus on individual, less social cultural environments in which people's understanding sexuality is formed. Objectives: The objectives this study were obtain updated baseline data allowing for a...
Achieving and maintaining viral suppression (VS) in pediatric populations remain suboptimal low- middle-income countries (LMICs), calling for the optimized management approaches. We compared rate of confirmed virological failure (cVF) associated factors among virally non-suppressed (VnS) children adolescents after enhanced adherence counseling (EAC) on dolutegravir-based versus other regimens. A multicentre prospective cohort study was conducted ART-experienced (<10 years) (10-19 with VnS...
Introduction: To end AIDS by 2030, barriers in accessing routine HIV testing services must be addressed, especially high-risk populations. Innovative strategies such as self-testing (HIVST) represent an opportunity to overcome the existing gaps. We aimed at characterizing first-time testers (HFTs) and evaluating effectiveness of HIVST among HFTs. Methods: A cross-sectional study was conducted three regions Cameroon. Oral kits were distributed using four distribution models: community model...
With the phase-out of stavudine (d4T), change to first-line regimens with zidovudine (AZT) or tenofovir (TDF) in resource-limited settings (RLS) might increase risks cross-resistance nucleos(t) ide reverse transcriptase inhibitors (NRTI). This would restrict scope switching World Health Organisation (WHO)-recommended standard second-line combinations (SLC) without HIV drug resistance (HIVDR)-testing routine clinical practice. An observational study was conducted among 101 Cameroonian...
<h3>ABSTRACT</h3> <h3>Background:</h3> Female sex workers (FSWs) in Cameroon commonly have unmet need for contraception posing a high risk of unintended pregnancy. Unintended pregnancy leads to range outcomes, and due legal restrictions, FSWs often seek unsafe abortions. Aside from the burden HIV, little is known about broader sexual reproductive health Cameroon. <h3>Methods:</h3> From December 2015 October 2016, we recruited aged ≥18 years through respondent-driven sampling across 5...
Background Scale-up of antiretroviral therapy (ART) in resource-limited settings has drastically reduced HIV-related morbidity and mortality. However, challenges long-term ART, adherence HIV drug resistance (HIVDR) itself, require monitoring to limit HIVDR emergence among ART-experienced populations, order ensure regimen efficacy. Methods A longitudinal study was conducted from 2009–2011 a cohort 141 HIV-infected adult patients (aged >21) at the national social insurance centre hospital...
Regular HIV testing is vital for timely linkage to the care continuum and ensuring success of behavioral biomedical interventions prevent acquisition. Men who have sex with men (MSM) are a key population prevention, treatment, efforts globally. This study measures factors associated prior among MSM in Cameroon.In 2011, 272 239 aged ≥ 18 were recruited from Douala Yaoundé respectively using respondent-driven sampling (RDS) cross-sectional surveillance study. Participants completed structured...
Background Men who have sex with men (MSM) in Cameroon consistently face significant stigma and discrimination. The urban HIV prevalence MSM is estimated at 35%. This study investigates the effect of stigma, discrimination alienation on Cameroonian MSM’s engagement treatment cascade. Methods: Qualitative interviews were semi-structured using a guide. Participants Douala, Ngaoundere, Bamenda, Bertoua Yaoundé asked to describe social structural context, knowledge existing HIV-related services...
Rapid scale-up of antiretroviral therapy (ART) and limited access to genotyping assays in low-resource settings (LRS) are inevitably accompanied by an increasing risk HIV drug resistance (HIVDR). The current study aims evaluate early warning indicators (EWI) as efficient strategy limit the development spread preventable HIVDR these settings, order sustain performance national rollout programmes. Surveys were conducted 2008, 2009 2010 within 10 Cameroonian ART clinics, based on five EWIs: (1)...
Background: Despite improvement in HIV prevention of mother-to-child transmission (PMTCT), there are still over 1,500 African infants newly infected daily. PMTCT elimination requires antiretroviral therapy (ART) throughout pregnancy and breastfeeding periods, while early infant diagnosis (EID) implies treatment for those infected. Our study aimed at assessing the utility EID program data evaluating implementation Cameroon, identifying efficacy existing interventions options on events...