- Global Maternal and Child Health
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Healthcare Systems and Reforms
- HIV, Drug Use, Sexual Risk
- Global Health Care Issues
- Adolescent Sexual and Reproductive Health
- Sex work and related issues
- Mobile Health and mHealth Applications
- HIV/AIDS drug development and treatment
- Virology and Viral Diseases
- Intimate Partner and Family Violence
- Medical Coding and Health Information
- Immunodeficiency and Autoimmune Disorders
- Chronic Disease Management Strategies
- Health disparities and outcomes
- Reproductive System and Pregnancy
- Child Nutrition and Water Access
- Vaccine Coverage and Hesitancy
- HIV/AIDS Impact and Responses
- Viral Infections and Outbreaks Research
- Immunotherapy and Immune Responses
- Reproductive tract infections research
- CRISPR and Genetic Engineering
- HIV-related health complications and treatments
Centre International De Reference Chantal Biya
2017-2024
Université de Yaoundé I
2017-2024
University of California, San Francisco
2024
University of Douala
2024
University of N'Djamena
2024
University of North Carolina at Greensboro
2024
Brandenburg University of Technology Cottbus-Senftenberg
2024
Centre Pasteur du Cameroun
2019
In Cameroon, like in many other resource-limited countries, data generated by health settings including morbidity and mortality parameters are not always uniform. the absence of a national guideline necessary for standardization harmonization data, precision required effective decision-making is therefore guaranteed. The objective present study was to assess reporting style healthcare settings. An institutional-based cross-sectional carried out from May June 2022 at Yaoundé Central Hospital....
<title>Abstract</title> Background Despite increasing awareness of socioeconomic status’s (SES) association with health outcomes, there is no widely accepted and rapidly implementable estimation SES measures in resource-limited settings. An exception the Demographic Health Surveys (DHS)’s wealth quintile index constructed from household ownership assets. To facilitate equity surveillance, method individual requiring fewer number assets needed. The objective this study was to identify DHS...
Background/Objectives: Over the past 50 years, developing new vaccines has been pivotal in responding to emerging and re-emerging diseases globally. However, despite substantial partner support, introducing sub-Saharan Africa remains challenging. This systematic review documents barriers vaccine introduction proposes evidence-based solutions. Methods: A comprehensive electronic search was conducted across five databases for articles published English or French on challenges of Africa. Three...
Current HCV treatments are genotype specific although potential pan-genotype have recently been described. Therefore, genotyping is an essential tool for the therapeutic management of infection and a variety technologies developed genotypes determination. Sequences analysis sub-genomic regions considered as gold standard widely used genotyping. Here, we compared using core NS5B in routine practice HCV-positive Cameroonian patients.All plasma samples received at Centre Pasteur Cameroon (CPC)...
Abstract Background Management of health data and its use for informed-decision making is a challenging sector aspect in developing countries. Monitoring evaluation interventions meeting health-related Sustainable Development Goals (SDGs), Cameroon Health Sector Strategy (HSS) targets facilitated through evidence-based decision-making public action. Thus, routine information system (RHIS) producing quality imperative. The objective this study was to assess the RHIS facilities (HFs) Yaoundé...
Abstract Introduction Gender-based violence (GBV) is a major public health problem that disproportionately affects women. In Cameroon, as well other countries worldwide, GBV has immediate effects on women’s health, with one in three women experiencing physical or sexual from an intimate partner, affecting their and reproductive health. The objective of this study was to determine the risks associated among Yaoundé. Methods A cross-sectional conducted Yaoundé (Cameroon), August October 2022....
Abstract Background Routine Health Information Systems (RHIS) of low-income countries function below the globally expected standard, characterised by production and use poor-quality data, or non-use good quality data for informed decision making. This has negatively influenced health service delivery uptake. study focuses on identifying factors associated with performance RHIS facilities (HF) in Yaoundé, so as to guide targeted strengthening. Methods A HF-based cross-sectional 6 districts...
Background Due to high HIV prevalence among Female Sex Workers (FSWs) in Cameroon (36.5%), this population is especially vulnerable acquisition and transmission nationwide. Though being prioritized the national response, it would be relevant generate statistics on number of FSWs order guide interventions FSWs. Our objective was estimate size within hotspots Cameroon. Methods A cross-sectional study conducted from September-November 2015 selected cities Cameroon: Bafoussam, Bamenda, Bertoua,...
One of the main reasons for risky sexual behavior observed in HIV serodiscordant couples despite knowledge partner's status and counselling is childbearing. In Cameroon, there are few reports on couples. This paper describes influence relationships decision to procreate.This cross-sectional study was conducted five health centers. Self-administered questionnaire used collect social demographic information, while semi-structured in-depth individual couple interviews were explore decisions...
Some risk factors for mother-to-child transmission (MTCT) of HIV have been identified. To further reduce MTCT, other were evaluated.A retrospective study on early infant diagnosis was conducted. Two-sided chi-square test used to assess associations with status.A total 15 233 HIV-infected mothers and 404 infants recruited. MTCT rate 9.34%. Only 3.8% born antiretroviral treatment infected. Under nevirapine, 4.1% increased infant' age at testing. Younger tend transmit more (P = 0.003). More...
Socio-demographic factors are important risk for HIV infection. Maternal socio-demographic associated with transmission from mother to child not well elucidated our knowledge. This study aimed assess the maternal vertical transmission.A matched case-control was conducted among children under 15 years of age born HIV-infected mothers; using a structured questionnaire. The in four health facilities North Region Cameroon July 2015 October 2016. HIV- infected were cases, and HIV-uninfected...
Diagnosis of tuberculosis still faces a lot challenges and is one the priorities in field management. Deciphering complex pathogenicity network could provide biomarkers for diagnosis. We discussed distribution HLA-B17, -DQB -DRB together with QuantiFERON test results infection. A case control study was done during which total 337 subjects were enrolled comprising 227 active (ATB), 46 latent infection (LTBI) 64 healthy controls (HC). Sequence-specific primer polymerase chain reaction immune...
Background: Children show various degrees of vulnerability regarding HIV infection and disease progression. This disparity presents challenges for the follow-up infected children. Here we investigated reasons behind this variability focusing on some host-related genes. Methods: We screened 570 Cameroonian children adolescents, aged 1 to 19 years old. Among them, 137 were followed over 4 years, from 2010 2015. Upon signing a proxy consent, adolescents classified according their age, CD4...
Malaria is still the primary cause of pediatric deaths. The efficient management malaria requires its rapid and accurate diagnosis. To fulfill this requirement, diagnostic tests have been developed, but their evaluation before commercialization never exhaustive. aim study was to evaluate performance a test (SD Bioline Antigen P.f/Pan) diagnose in children.Testing conducted on children aged between 6 months 15 years who were examined at "Centre Mère Enfant (CME) "Chantal Biya" Foundation...
Human leukocyte antigen (HLA) molecules play a key role in the cellular immune system. They may be determinants of mother-to-child transmission which is driving force pediatric HIV infection. We intended to look at impact distribution these polymorphic HLA genes (MTCT) Cameroon.
Abstract Worldwide, the Joint Monitoring Program reports that one in four health care facilities (HCFs) lack functional water supply on premises, three hand hygiene facilities, and adequate infectious waste disposal. The COVID-19 pandemics shed light of investments, absence infrastructures, education policies related to WASH as well revealed insufficient investment healthcare safety has brought services non-negotiable for HCFs. This study used a cross-sectional pre-post framework determine...
<title>Abstract</title> <bold>Introduction: </bold>Gender-based violence (GBV) is a major public health problem that disproportionately affects women. In Cameroon, as well other countries worldwide, GBV has immediate effects on women's health, with one in three women experiencing physical or sexual from an intimate partner, affecting their and reproductive health. The objective of this study was to determine the risks associated among Yaoundé. <bold>Methods: </bold>A cross-sectional...
Background: HIV case finding is an essential component for ending AIDS, but there limited evidence on the effectiveness of such a strategy in pediatric population. We sought to determine positivity rates among children according entry points Cameroon. Methods: A facility-based survey was conducted from January 2015 December 2019 mother–child couples at various health facilities six regions questionnaire administered parents/guardians. Children were tested by polymerase chain reaction (PCR)....
HIV infection and its progression to AIDS depend on several factors including host genetic factors. The immunological mechanisms of resistance greatly influence the prevalence in a given region. Worldwide, Cameroon not exempted, frequency AIDS-associated genes varies may this prevalence. North Far Regions have had lowest country for many years despite risky behaviors associated with their customs habits. In work, we seek explore contribution low these regions.
Abstract Background Worldwide, the Joint Monitoring Program reports that one in four health care facilities (HCFs) lack functional water supply on premises, three hand hygiene facilities, and adequate infectious waste disposal. The COVID-19 pandemics shed light of investments, absence infrastructures, education policies related to WASH as well revealed insufficient investment healthcare safety; has brought services non-negotiable for HCFs. Methods This study used a cross-sectional pre-post...
Abstract Objective In 2014, the Joint United Nations Program on HIV and AIDS (UNAIDS) partners set ‘90-90-90 targets’. Many countries are facing challenge of estimating first 90. Our objective was to propose an alternative modelling procedure, discuss its usefulness for taking into account duplication. Results For deduplication, we identified two important ingredients: probability HIV+ person being re-tested during period average number tests. Other adjusted factors included: false positive...