A5017672139- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Cervical Cancer and HPV Research
- Cancer-related molecular mechanisms research
- Sarcoma Diagnosis and Treatment
- MicroRNA in disease regulation
- Ectopic Pregnancy Diagnosis and Management
- Genital Health and Disease
- Testicular diseases and treatments
- PARP inhibition in cancer therapy
- Circular RNAs in diseases
- Cancer Risks and Factors
- Ovarian function and disorders
- BRCA gene mutations in cancer
- Pelvic and Acetabular Injuries
- Gynecological conditions and treatments
- Reproductive System and Pregnancy
- Assisted Reproductive Technology and Twin Pregnancy
- Estrogen and related hormone effects
- Pregnancy and preeclampsia studies
- Cultural and Sociopolitical Studies
- Gestational Trophoblastic Disease Studies
Istanbul University
2016-2025
Eskişehir City Hospital
2021
Istanbul Medeniyet University
2021
Npistanbul Brain Hospital
2021
Fatih University
2020
Fatih University Medical Faculty Hospital
2019
Gynecologic Oncology Group
2019
Adli Tıp Kurumu
2018
Beijing Obstetrics and Gynecology Hospital
2012
The aim of this study was to evaluate the diagnostic value 2-(fluorine-18)-fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/CT in comparison with MRI for detection recurrent ovarian cancer.Forty-seven patients suspected cancer recurrence after total ablative or cytoreductive surgery, as well neoadjuvant adjuvant chemotherapy, who had undergone (18)F-FDG imaging were recruited present study. All also underwent within a month same purpose. Recurrent abdomen and pelvis evaluated each 47 classified...
<b><i>Background:</i></b> In subtypes of non-endometrioid endometrium cancers (non-ECC), it is not clear whether the omentectomy a part debulking if visual assessment normal. Recently, ESMO-ESGO-ESTRO Endometrial Consensus Conference Working Group in their report titled “Endometrial Cancer: diagnosis, treatment and follow-up” recommended that be performed serous subtype, but carcinosarcoma, undifferentiated endometrial carcinoma or cell. this study, question should...
This study was conducted to determine the demographic and clinicopathologic characteristics evaluate prognostic value of various factors, such as extensiveness surgery, related tumour itself clinical features in recurrence borderline ovarian tumours (BOT). We retrospectively evaluated data 103 patients with a treated at our institution between years 2000 2012. The median age 37 (16–79) majority were premenopausal (76.7%). During follow-up, 16 recurrences observed (15.5%). multivariate...
Abstract Aim of the present analysis is to compare impact antihormonal therapy versus cytotoxic chemotherapy a watch wait approach on disease-free survival (DFS) in adjuvant setting patients who underwent complete cytoreductive surgery(CRS) for recurrent adult type granulosa cell tumours ovary (GCT). Moreover, we wished identify prognostic risk factors recurrence. We included GCT-patients CRS resulting total macroscopic tumour clearance, treated two gynaecological cancer centres over 20-year...
Abstract Background In patients with ulcerative colitis, histological healing is associated better clinical outcomes1. Therefore,histological remission as the treatment target advocated. observational studies2,3 have shown that in endoscopic, longer relapse-free survival, reduced hospitalization rates, corticosteroid use rates. Methods Demographic information, laboratory findings, courses of colitis who had disease clearance, were evaluated retrospectively for 5 years. The files 529 scanned,...
Background and Objectives: Epithelial ovarian–tubal–peritoneal cancer (EOC) is the most common type of ovarian cancer. Optimal cytoreductive surgery important prognostic factor in its management. When complete cytoreduction anticipated to be challenging, neoadjuvant systemic chemotherapy (NACT) becomes an alternative. Imaging modalities are utilized decision-making process for primary treatment. The purpose this study evaluate diagnostic performance accuracy preoperative MRI, CT, 18F-FDG...
To compare the detection rates and diagnostic accuracy of sentinel lymph node (SLN) mapping using carbon dye indocyanine green (ICG) in patients with early-stage endometrial cancer. The present study was a dual-center, prospective cohort conducted between September 2021 August 2022 involving For SLN mapping, one center exclusively used dye, while other solely ICG. Subsequently, all underwent complete systematic pelvic lymphadenectomy. rates, sensitivity, negative predictive value were...
Crush injuries pose significant challenges for replantation due to extensive vascular and nerve damage. Vein grafts help overcome defects in such cases, increasing the likelihood of successful revascularization. In this report, we present case a 14-year-old male who suffered subtotal amputations at mid-metacarpal level crush injury. Three fingers were revascularized using single Psi (Ψ)-shaped vein graft with three branches, from distal volar surface forearm. The ulnar artery was used...
Undifferentiated/dedifferentiated endometrial carcinomas (UCE/DCEs) of the endometrium are rare tumors with poor prognosis. There few clinicopathologic studies detailed immunohistochemical analysis regarding UCE/DCEs. We evaluated diagnostic value a selected tumor stem-cell marker and epithelial-mesenchymal transition (EMT) markers, in addition to previously studied markers identifying UCE/DCEs from other types high-grade carcinomas. Eleven cases complete clinical follow-up that were...
TPS5603 Background: There is a significant unmet need to develop new regimens for BRCA1/2-nonmutated advanced ovarian cancer (OC). The PARP inhibitor olaparib approved women with platinum-sensitive, recurrent OC regardless of BRCA1/2 status and, more recently, newly diagnosed BRCA-mutated OC. In the TOPACIO/KEYNOTE-162 study, combination PD-1–blocking antibody pembrolizumab (pembro) and niraparib demonstrated efficacy in platinum-resistant relapsed OCirrespective status....
Abstract Aim Endometrial cancer is the most common of female reproductive tract in developed countries. There are many risk factors defined for development endometrial cancer, including obesity. We aimed to evaluate significance adiposity on survival outcomes patients with cancer. Methods The diagnosed and underwent surgery between April 2009 October 2017 were retrospectively reviewed. visceral adipose tissue subcutaneous volumes measured at level umbilicus single‐slice magnetic resonance...
Epithelial ovarian cancer (EOC) is the type of OC with highest mortality rate. Due to asymptomatic nature disease and few available diagnostic tests, it mostly diagnosed at advanced stage. Therefore, present study aimed discover predictive and/or early novel circulating microRNAs (miRNAs or miRs) for EOC. Firstly, microarray analysis miRNA expression levels was performed on 32 samples female individuals: Eight plasma from patients pathologically confirmed EOC (mean age, 45 (30-54) years),...
The aim of the study was to describe clinicopathologic characteristics, survival outcomes and factors associated with recurrence in patients diagnosed synchronous primary endometrial epithelial ovarian cancers.In this retrospective study, 50 who were cancers underwent surgery between 1998 2010 reviewed.In our median age at time diagnosis 53 years (range 28-79). most common presenting symptom abnormal uterine bleeding a ratio 36%. Fifty-four percent had endometrioid type cancer cancer. All...
The purpose of this study was to investigate the outcomes and prognostic factors metastasectomy in patients with metastatic ovarian tumors from extragenital primary sites.All pathologically confirmed between January 1997 June 2015 were included study. A total 131 identified. data obtained patients' medical records. Clinicopathological features evaluated by both univariate multivariate analyses.The sites colorectal region (53.4%), stomach (26%), breast (13%). Preoperative serum CA 125 19-9...