A5035294622- Pickering emulsions and particle stabilization
- Cellular Mechanics and Interactions
- Material Dynamics and Properties
- Microfluidic and Bio-sensing Technologies
- Electrostatics and Colloid Interactions
- Surfactants and Colloidal Systems
- Force Microscopy Techniques and Applications
- Particle physics theoretical and experimental studies
- Microtubule and mitosis dynamics
- Diffusion and Search Dynamics
- interferon and immune responses
- Particle Dynamics in Fluid Flows
- Micro and Nano Robotics
- Minerals Flotation and Separation Techniques
- RNA Research and Splicing
- Quantum Chromodynamics and Particle Interactions
- Lower Extremity Biomechanics and Pathologies
- Atmospheric chemistry and aerosols
- Atmospheric aerosols and clouds
- Neutrino Physics Research
- Field-Flow Fractionation Techniques
- Slime Mold and Myxomycetes Research
- Characterization and Applications of Magnetic Nanoparticles
- Healthcare Operations and Scheduling Optimization
- Molecular Communication and Nanonetworks
Max Planck Institute for Dynamics and Self-Organization
2022-2024
University of Milan
1997-2023
Institute of Biomedical Technologies
2020-2023
Mylan (South Africa)
2021
Laboratoire Charles Coulomb
2016-2019
Université de Montpellier
2018-2019
Università Cattolica del Sacro Cuore
2012-2016
Catholic University of America
2016
University of Milano-Bicocca
2016
Fédération Internationale de Football Association
2014
Abstract The process in which locally confined epithelial malignancies progressively evolve into invasive cancers is often promoted by unjamming, a phase transition from solid-like to liquid-like state, occurs various tissues. Whether this tissue-level mechanical impacts phenotypes during carcinoma progression remains unclear. Here we report that the large fluctuations cell density accompany unjamming result repeated deformations of cells and nuclei. This triggers cellular mechano-protective...
Innovations in supply chain (SC) management are rapidly spreading public healthcare sectors across developed countries. In particular, managers and policymakers view SC innovation as a way to lower costs improve quality. However, although the related rhetoric is strong, literature provides little evidence of benefits performance such initiatives. Above all, lacks sound conceptual framework for appraising organisations. We argue that nature specificities context require specific theoretical...
Mineral dust aerosol (dust) is widely recognized as a fundamental component of the climate system and closely coupled with glacial-interglacial oscillations Quaternary period. However, direct impact on energy balance Earth remains poorly quantified, mainly because uncertainties in radiative properties, which vary greatly over space time. Here we provide first measurements optical thickness particles windblown to central East Antarctica (Dome C) during last glacial maximum (LGM) Holocene. By...
Cells often migrate on curved surfaces inside the body, such as tissues, blood vessels or highly protrusions of other cells. Recent \textit{in-vitro} experiments provide clear evidence that motile cells are affected by curvature substrate which they migrate, preferring certain curvatures to others, termed ``curvotaxis". The origin and underlying mechanism gives rise this sensitivity not well understood. Here, we employ a ``minimal cell" model is composed vesicle contains membrane protein...
Characterizing nano- and micro-particles in fluids still proves to be a significant challenge for both science industry. Here, we show how determine shape size distributions of polydisperse water suspensions micron-sized particles by the analysis field scattered forward direction single illuminated laser beam. We exploit novel Single Particle Extinction Scattering method connection with shear conditions which give preferred orientations passing through scattering volume. Water calibrated...
<title>Abstract</title> Breast cancer progression is driven by dynamic changes in tissue mechanics that promote phase transitions toward collective cell movement, immune activation, and invasion. While previous investigations primarily employed model systems of genetically identical cells, breast carcinoma consists heterogeneous populations varying genetic mechanical traits. The complex interplay between this diversity dynamics, affecting tumor progression, remains largely unexplored. Here,...
The current literature on the enabling conditions of multidisciplinary teams focuses singular dimensions organizations (i.e., human resources, clinical pathways, objects) without shedding light to way in which these organizational factors interact and mutually influence one another.Drawing a system perspective organizations, authors analyze patterns that promote support how they interrelate enforce organization work system.The develop modified sociotechnical (STS) model understand two...
We propose a new tracking-free method for the quantification of multiscale dynamics in 2D and 3D cell collectives.
We report the measurement of interaction energy between a charged Brownian polystyrene particle and an air-water interface. The potential is obtained from Boltzmann equation by tracking interface distance with specifically designed Dual-Wave Reflection Interference Microscopy (DW-RIM) setup. has two equilibrium positions located at few hundreds nanometers farthest position well accounted DLVO model complemented gravity. closest one, not predicted current models, more frequently appears in...
Abstract The connection between the properties of a cell tissue and those single constituent cells remains to be elucidated. At purely mechanical level, degree rigidity different cellular components, such as nucleus cytoplasm, modulates interplay inner processes external environment, while simultaneously mediating interactions neighboring cells. Being able quantify correlation single-cell would improve our mechanobiological understanding tissues. Here we develop methodology quantitatively...
Direct observation of the microscopic material structure and dynamics during rheological shear tests is goal rheo-microscopy experiments. Microscopically, they shed light on many mechanisms processes that determine mechanical properties at macroscopic scale. Moreover, permit for determination actual deformation field, which particularly relevant to assess banding or wall slip. While sample probing achieved by a variety custom commercial instruments, possibility performing quantitative...
Drugs targeting microtubules rely on the mitotic checkpoint to arrest cell proliferation. The prolonged induced by such drugs is followed a G1 arrest. Here, we follow for several weeks fate of G1-arrested human cells after treatment with nocodazole. We find that small fraction escapes from and resumes These escaping experience reduced DNA damage p21 activation. Cells surviving are enriched anti-apoptotic proteins, including Triap1. Increasing Triap1 levels allows survive first lower p21;...
Background: The current literature on the enabling conditions of multidisciplinary teams focuses singular dimensions organizations (human resource management, clinical pathways, objects), without shedding light to way in which these organizational factors interact and mutually influence each other. Purpose: Drawing a system perspective organizations, authors analyze patterns that promote support how they interrelate enforce organization work system. Methodology/Approach: develop modified...
Abstract The process in which locally confined epithelial malignancies progressively evolve into invasive cancers is often promoted by unjamming, a phase transition from solid-like to liquid-like state that occurs various tissues. Whether this tissue-level mechanical impact phenotypes during carcinoma progression remains unclear. We show, here the large fluctuations cell density accompany unjamming result repeated deformations of cells and nuclei. Cells react these protracted stresses...