A5100676990- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Algal biology and biofuel production
- Biofuel production and bioconversion
- Enzyme Production and Characterization
- Microbial Metabolites in Food Biotechnology
- Electrochemical sensors and biosensors
- Analytical Chemistry and Chromatography
- Angiogenesis and VEGF in Cancer
- Viral Infectious Diseases and Gene Expression in Insects
- Phytochemical compounds biological activities
- Pharmacogenetics and Drug Metabolism
- Antioxidant Activity and Oxidative Stress
- Protein Tyrosine Phosphatases
- Advanced biosensing and bioanalysis techniques
- Cancer, Lipids, and Metabolism
- Chemical Synthesis and Reactions
- Fluid Dynamics and Mixing
- Bioactive Compounds and Antitumor Agents
- Biotin and Related Studies
- Cancer Mechanisms and Therapy
- Cancer-related molecular mechanisms research
- Food Quality and Safety Studies
- Lipid metabolism and biosynthesis
- Carbohydrate Chemistry and Synthesis
Zhejiang University of Technology
2013-2024
Guangxi Medical University
2024
Nanjing Forestry University
2024
The First Affiliated Hospital, Sun Yat-sen University
2008-2023
Sun Yat-sen University
2008-2023
Fudan University
2002-2022
Chongqing Medical University
2019-2022
University of Shanghai for Science and Technology
2022
China Agricultural University
2021
Shandong University
2021
Integrated clustered regularly interspaced short palindromic repeat (CRISPR)-loop-mediated amplification (LAMP) technology is of great importance in CRISPR-based diagnostic systems, which urgently needs to be developed improve accuracy. A labor-free, contamination-free, and fully automated droplet manipulation platform for the CRISPR-LAMP has not been before. Herein, we propose a platform, can precisely manipulate perform combined reactions with high sensitivity specificity. SARS-CoV-2 Spike...
Hepatocellular carcinoma (HCC) is one of the most common types primary liver cancer and third frequent cause death worldwide. Diethylnitrosamine (DEN) recognized risk factors for hepatocarcinogenesis likely due to CYP2E1-mediated metabolic activation. However, DEN activity in non-neoplastic tissue from HCC patients has not been determined; role CYP2E1 activity, particular constitutive inhibited with respect induced by yet clear. Herein, we determined found that was significantly elevated a...
ABSTRACT Rabies remains a public health threat in most parts of the world, and approximately 99% cases are transmitted by dogs. There is an urgent need to develop efficacious affordable vaccine control canine-transmitted rabies developing countries. Our previous studies demonstrate that overexpression chemokines/cytokines such as CCL-3 (MIP-1α) granulocyte-macrophage colony-stimulating factor (GM-CSF) can enhance immunogenicity vaccines. In present study, chemokine CXCL13 was inserted into...
The phytohormone 6-benzylaminopurine (6-BAP) significantly improves lipid synthesis of oleaginous microorganisms with the great potential applied in production. In current study, and DHA productions Aurantiochytrium sp. were found to be improved by 48.7% 55.3%, respectively, induced 6-BAP treatments. Then, using high-throughput RNA-seq technology, overall de novo assembly cDNA sequence data generated 53871 unigenes, 15902 these annotated at least one database. comparative transcriptomic...
Abstract Background The role of cholesterol metabolism in gastric cancer (GC) and its implications for tumor characteristics immunotherapy response remain poorly understood. In this study, our aim was to investigate role, identify associated metabolic subtypes, assess their clinical GC. Methods We conducted a comprehensive analysis genes (CMGs) using transcriptomic data from TCGA GEO. Based on 23 representative CMGs, we classified GC into subtypes. evaluated features immune cell infiltration...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHeterogeneous permanganate oxidations. 5. The preparation of aldehydes by oxidative cleavage carbon-carbon double bondsDonald G. Lee, Tao Chen, and Zhao WangCite this: J. Org. Chem. 1993, 58, 10, 2918–2919Publication Date (Print):May 1, 1993Publication History Published online1 May 2002Published inissue 1 1993https://pubs.acs.org/doi/10.1021/jo00062a046https://doi.org/10.1021/jo00062a046research-articleACS PublicationsRequest reuse...
Combining statin and fibrate in clinical practice provides a greater reduction of triglycerides than either drug given alone, but the mechanism for this effect is poorly understood. Apolipoprotein AV (apoAV) has been implicated triglyceride metabolism. This study was designed to investigate combination on apoAV underlying mechanism(s).Hypertriglyceridaemia induced rats by giving them 10% fructose drinking water 2 weeks. They were then treated with atorvastatin, fenofibrate or two agents...
// Sile Chen 1, * , Xinhua Zhang Jianjun Peng 1 Ertao Zhai Yulong He Hui Wu Chuangqi Jinping Ma Zhao Wang Shirong Cai Department of Gastrointestinal Surgery Center, The First Affiliated Hospital Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China These authors have contributed equally to this work Correspondence to: Cai, e-mail: caishirong420@163.com Keywords: gastric cancer, angiogenesis, immunohistochemistry, ERK/AKT pathway Received: June 16, 2015 Accepted: January 17,...
Retinoids display anti-tumour activity on various cancer cells and therefore have been used as important therapeutic agents. However, adverse side effects RA (retinoic acid) resistance limit further development clinical application of retinoid-based We report in the present paper identification a natural marine product that activates RARs (RA receptors) with chemical structure distinct from retinoids by high-throughput compound library screening. Luffariellolide was uncovered novel RAR...
Calcitonin gene-related peptide (CGRP) contributes to bone formation by stimulating marrow stromal cell (BMSC) proliferation and differentiation. However, the proliferative apoptotic effects of CGRP on marrow-derived endothelial progenitor cells (EPCs) have not been investigated. We tested EPC apoptosis Cell Counting Kit-8, flow cytometry, studied expression proliferation- apoptosis-related markers in EPCs underlying mitogen-activated protein kinase (MAPK) signalling pathway quantitative...